For citations statistics, see:
Note: *Corresponding author(s) of the papers.
22. Tiago Carvalho: “Design of novel protein fibrils-based biomaterials for the regeneration of injured myocardium tissue”, 2023. (co-supervision).
Final grade: Approved/passed
22. Ruoyu Cheng: "Smart nanoparticle-based platforms for regulating tumor microenvironment and cancer immunotherapy", 2023. Double degree between the University of Helsinki and University of Groningen.
Final grade: Approved/passed
21. Giulia Torrieri: "Development of drug-loaded acetalated dextran-based nanoparticles for hear targeting and treatment of myocardial infarction", 2022.
Final grade: Approved/passed
20. Pei Zhang: "Development of peptide and protein microparticles for diabetes therapy: From fabrication to in vivo evaluation", 2022. (co-supervision)
Final grade: Approved/passed
19. João Pedro Martins: "Neonatal Fc receptor-targeted nanoparticles for oral delivery of anti-diabetic drugs", 2021.
Final grade: Approved/passed with distinction/honors
18. Nazanin Zanjanizadeh Ezazi: "Development and characterization of conductive drug-loaded scaffolds for tissue engineering applications", 2021.
Final grade: Approved/passed
17. Feng Zhang: "Development of transformable nanotherapeutics for cancer therapy", 2021.
Final grade: Approved/passed with distinction/honors
16. Nadeem Muhammad Hafeez: "Tendon regeneration via targeted delivery of immune modulators through liposomal nanoparticles", 2021. (co-supervision)
Final grade: Approved/passed with distinction/honors
15. Patrícia Figueiredo: "Development of lignin-based nanoparticles for cancer therapy", 2020.
Final grade: Approved/passed with distinction/honors
14. Tomás Ramos: "Thernostic nanocomposites for cancer immunotherapy", 2020. (co-supervision)
Final grade: Approved/passed with distinction/honors
13. Zehua Liu: "Porous silicon-based on-demand nanohybrids for biomedical applications", 2019.
Final grade: Approved/passed with distinction/honors
12. Flavia Fontana: "Biohybrid cloaked nanovaccines for cancer immunotherapy", 2019.
Final grade: Approved/passed with distinction/honors
11. Patrick Vingadas Almeida: "Multifunctional porous silicon based nanocomposites
for cancer targeting and drug delivery" 2018.
Final grade: Approved/passed
10. Jukka Saarinen: "Non-linear label-free optical imaging of cells, nanocrystal cellular uptake and solid-state analysis in pharmaceutics" 2018. (co-supervision)
Final grade: Approved/passed
9. Mónica P. A. Ferreira: "Multifunctional nanoparticles for targeted drug delivery and imaging for ischemic myocardial injury" 2017.
Final grade: Approved/passed with distinction/honors
8. Francisca Araújo: "Glucagon-like peptide-1 nanotechnology based systems for prevention and therapy of diabetes" 2017. (co-supervision)
Final grade: Approved/passed with distinction/honors
7. Bárbara Herranz-Blanco: "Multi-approach design and fabrication of hybrid composites for drug delivery and cancer therapy" 2016.
Final grade: Approved/passed
6. Neha Shrestha: "Mesoporous silicon systems for oral protein/peptide-based diabetes mellitus therapy" 2016.
Final grade: Approved/passed with distinction/honors
5. Chang-Fang Wang: "Chemical surface modification of porous silicon nanoparticles for cancer therapy" 2015.
Final grade: Approved/passed
4. Mohammad Ali Shahbazi: "Effect of surface chemistry on the immune responses and cellular interactions of porous silicon nanoparticles" 2015.
Final grade: Approved/passed with distinction/honors
3. Dongfei Liu: "Porous silicon-based multicomposites for controlled drug delivery" 2014.
Final grade: Approved/passed with distinction/honors
2. Luis Bimbo: "Biocompatibility and biofunctionalization of mesoporous silicon particles", 2012.
Final grade: Approved/passed with distinction/honors
1. Tarja Limnell: "Mesoporous silica- and silicon-based materials as carriers for poorly water soluble drugs", 2011. (co-supervision)
Final grade: Approved/passed
Manlio Fusciello, Flavia Fontana, Siri Tähtinen, Cristian Capasso, Sara Feola, Beatriz Martins, Jacopo Chiaro, Karita Peltonen, Leena Ylösmäki, Erkko Ylösmäki, Firas Hamdan, Otto K. Kari, Joseph Ndika, Harri Alenius, Arto Urtti, Jouni T. Hirvonen, Hélder A. Santos*, Vincenzo Cerullo*, “Artificially Cloaked Viral Nanovaccine for Cancer Immunotherapy”, Nature Commun. 2019, 10, 5747.
Tuying Yong, Xiaoqiong Zhang, Nana Bie, Hongbo Zhang, Xuting Zhang, Fuying Li, Abdul Hakeem, Jun Hu, Lu Gan*, Hélder A. Santos*, Xiangliang Yang*, “Tumor Exosome-Based Nanoparticles are Efficient Drug Carriers for Chemotherapy”, Nature Commun. 2019, 10(1), 3838.
Hongbo Zhang, Wenguo Cui, Xiangmeng Qu, Huayin Wu, Liangliang Qu, Xu Zhang, Ermei Mäkilä, Jarno Salonen, Yue-Qi Zhu*, Zhou Yang, Dong Chen, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Photothermal Responsive Nanosized Hybrid Polymersome as Versatile Therapeutics Co-Delivery Nanovehicle for Effective Tumor Suppression”, Proc. Natl. Acad. Sci. U.S.A. 2019, 116(16) 7744–7749.
Flavia Fontana, Manlio Fusciello, Christianne Groeneveldt, Cristian Capasso, Jacopo Chiaro, Sara Feola, Zehua Liu, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Vincenzo Cerullo*, Hélder A. Santos*, “Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor”, ACS Nano 2019, 13(6), 6477–6490.
Zehua Liu, Yunzhan Li, Wei Li*, Wenhua Lian, Marianna Kemell, Sami Hietala, Patrícia Figueiredo, Li Li, Ermei Mäkilä, Ming Ma, Jarno Salonen, Jouni T. Hirvonen, Dongfei Liu, Hongbo Zhang*, Xianming Deng*, Hélder A. Santos*, “Close-loop Dynamic Nanohybrids on Collagen-Ark with In-situ Gelling Transformation Capability for Bio-mimetically Stage Specific Diabetic Wound Healing”, Mater. Horiz. 2019, 6, 385–393.
Patrícia Figueiredo*, Kalle Lintinen, Jouni T. Hirvonen, Mauri A. Kostiainen, Hélder A. Santos*, “Properties and Chemical Modifications of Lignin: Towards Lignin-Based Nanomaterials for Biomedical Applications”, Prog. Mater. Sci. 2018, 93, 233–269. (Review)
João P. Martins*, Roberto D’Auria, Dongfei Liu, Flavia Fontana, Mónica P. A. Ferreira, Alexandra Correia, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Luca Casettari, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Engineered Multifunctional Albumin-Decorated Porous Silicon Nanoparticles for FcRn Translocation of Insulin”, Small 2018, 14(27), 1800462.
Mónica P.A. Ferreira*, Virpi Talman, Giulia Torrieri, Dongfei Liu, Gonçalo Marques, Karina Moslova, Zehua Liu, João F. Pinto, Jouni Hirvonen*, Heikki Ruskoaho*, Hélder A. Santos*, “Dual-Drug Delivery Using Dextran-Functionalized Nanoparticles Targeting Cardiac Fibroblasts for Cellular Reprogramming”, Adv. Funct. Mater. 2018, 28(15), 1705134.
Zehua Liu, Yunzhan Li, Wei Li, Chen Xiao, Dongfei Liu, Chao Dong, Ming Zhang, Ermei Mäkilä, Marianna Kemell, Jarno Salonen, Jouni T. Hirvonen, Hongbo Zhang*, Dawang Zhou*, Xianming Deng*, Hélder A. Santos*, “Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics”, Adv. Mater. 2018, 30(24), 1703393.
Flavia Fontana*, Mohammad-Ali Shahbazi, Dongfei Liu, Hongbo Zhang, Ermei Mäkilä, Jarno Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy”, Adv. Mater. 2017, 29(7), 1603239.
Dongfei Liu*, Hongbo Zhang, Salvatore Cito, Jin Fan, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Tiina M. Sikanen, David A. Weitz, Hélder A. Santos*, “Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation”, Nano Lett. 2017, 17(2), 606–614.
Mónica P.A. Ferreira*, Sanjeev Ranjan, Sini Kinnunen, Alexandra Correia, Virpi Talman, Ermei Mäkilä, Brianda Barrios-Lopez, Marianna Kemell, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Heikki Ruskoaho*, Anu J. Airaksinen*, Hélder A. Santos*, “Drug-loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling”, Small 2017, 13(33), 1701276.
431. Ayeh Bani Saeid, Gabriele De Rubis, Kylie A. Williams, Stewart Yeung, Dinesh Kumar Chellappan, Sachin Kumar Singh, Gaurav Gupta, Philip M. Hansbro, Mohammad-Ali Shahbazi, Monica Gulati, Indu Pal Kaur, Hélder A. Santos, Keshav Raj Paudel*, Kamal Dua*, “Revolutionising Lung Health: Exploring the Latest Breakthroughs and Future Prospects of Synbiotic Nanostructures in Lung Diseases”, Chem. Biol. Interact. 2024. (in press)
430. Sandra López-Cerdá*, Giuseppina Molinaro, Ruben Pareja Tello, Alexandra Correia, Sarojinidevi Künig, Peter Steinberger, Michael Jeltsch, Jouni T. Hirvonen, Goncalo Barreto, Johannes Stoeckl*, Hélder A. Santos*, “Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid−Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy”, ACS Appl. Mater. Interfaces 2024. (in press)
429. Filipe V. Ferreira*, Nazanin Z. Ezazi, Caio G. Otoni, Ana Carolina Aguiar, Jhonatan R. O. Bianchi, João H. Lopes, Danilo M. dos Santos, Luiz G. Greca, Hernane S. Barud, Hélder A. Santos, Orlando J. Rojas*, Luiz Henrique Capparelli Mattoso, “In Situ Biofabrication of Microbial Cellulose Capsules Carrying Cubosomes: Toward Colon Targeted Multidrug Delivery”, ACS Appl. Polym. Mater. 2024, 6(7), 3708–3720. (Issue's cover image)
428. Flavia Fontana*, Giuseppina Molinaro, Sofia Moroni, Giulia Pallozzi, Mónica P. A. Ferreira, Rubén Pareja Tello, Khalil Elbadri, Giulia Torrieri, Alexandra Correia, Marianna Kemell, Luca Casettari, Christian Celia, Hélder A. Santos*, “Biomimetic Platelet-Cloaked Nanoparticles for the Delivery of Anti-inflammatory Curcumin in the Treatment of Atherosclerosis”, Adv. Healthcare Mater. 2024. (in press)
427. Soraia Filipa Tavares Pinto, Hélder Almeida Santos, Bruno Filipe Carmelino Cardoso Sarmento*, “New Insights Into Nanomedicines for Oral Delivery of Glucagon-like Peptide-1 Analogs”, WIRES Nanomed. Nanobi. 2024, 16(2), e1952.
426. Gabriela Corrêa Carvalho, Gabriel Davi Marena, André Luiz Carneiro Soares do Nascimento, Bruna Almeida Furquim de Camargo, Rafael Miguel Sábio, Felipe Rebello Lourenço, Hélder A. Santos*, Marlus Chorilli*, “Physicochemical Characterization of a Lycopene-Loaded Mesoporous Silica Nanoparticle Formulation”, Nano Select 2024. (in press)
425. Miquel Martínez-Navarrete, Antonio José Guillot*, Maria C. Lobita, María Carmen Recio, Rosa Giner, Juan Aparicio-Blanco, María Carmen Montesinos, Hélder A. Santos, Ana Melero, “Cyclosporin A-Loaded Dissolving Microneedles for Dermatitis Therapy: Development, Characterisation and Efficacy in a Delayed-Type Hypersensitivity In Vivo Model”, Drug Deliv. and Transl. Res. 2024. (in press)
424. Pei Zhang, Erik Niemelä, Sandra López Cerdá, Pasi Sorvisto, Jani Virtanen, Hélder A. Santos*, “Host-Directed Virus-Mimicking Particles Interacting with the ACE2 Receptor Competitively Block Coronavirus SARS-CoV-2 Entry”, Nano Lett. 2024, 24(14), 4055–4063. (Issue's cover image)
423. Xiangmeng Qu, Hongbo Zhang, Haixin Kong, Dong Chen, Zhou Yang, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Porous Silicon Nanoparticles Conjugated Magnetite-Chitosan Graphene Oxide Nanoparticles for Effective Removal of Complex Pollutants”, Adv. Sustain. Syst. 2024, 2300471. (in press)
422. Mina Mohammadi, Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Mahsa Akbari, Saman Rezaei, Kiyan Musaie, Mohammad Reza Eskandari, Hélder A. Santos*, Narges Poursina*, Mohammad-Ali Shahbazi*, “Diatom-Guided Bone Healing via a Hybrid Natural Scaffold”, Heliyon 2024, 10, e25878.
421. Jiahui Zhang, Jianmei Gu, Xu Wang, Cheng Ji, Dan Yu, Maoye Wang, Jianming Pan, Hélder A. Santos*, Hongbo Zhang*, Xu Zhang*, “Engineering and Targeting Neutrophils for Cancer Therapy”, Adv. Mater. 2024, 2310318. (in press)
420. Siyu Fan, Han Gao, Yue Zhang, Linyan Nie, Raquel Bártolo, Reinier Bron, Hélder A. Santos, Romana Schirhagl*, “Quantum Sensing of Free Radical Generation in Mitochondria of Single Heart Muscle Cells during Hypoxia and Reoxygenation”, ACS Nano 2024, 18(4), 2982–2991.
419. Soraia Pinto, Mahya Hosseini, Stephen T. Buckley, Wen Yin, Javad Garousi, Torbjörn Gräslund, Sven van Ijzendoorn, Hélder A. Santos*, Bruno Sarmento*, “Nanoparticles Targeting the Intestinal Fc Receptor Enhance Intestinal Cellular Trafficking of Semaglutide”, J. Control. Release 2024, 366, 621-636.
418. Soraia Pinto, Mahya Hosseini, Stephen T. Buckley, Wen Yin, Javad Garousi, Torbjörn Gräslund, Sven van Ijzendoorn, Hélder A. Santos*, Bruno Sarmento*, “Inside Back Cover: Nanoparticles Targeting the Intestinal Fc Receptor Enhance Intestinal Cellular Trafficking of Semaglutide”, J. Control. Release 2024, 366, IBC. (Issue's Inside Back Cover)
417. Shuodan Huang, Yan Gao, Huiying Li, Ruoran Wang, Xiaomei Zhang, Xiaoyu Wang, Di Huang, Linxuan Zhang, Hélder A. Santos*, Zhenyu Yin*, Bing Xia*, “Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages”, Adv. Mater. 2024, 36(5), 2310979.
416. Rafael Miguel Sábio, Gabriela Corrêa Carvalho, Jiachen Li, Marlus Chorilli, Hélder A. Santos*, “Advanced Porous Materials for Antimicrobial Treatment”, Nano Select 2023, 1-20. (Review)
415. Nesma El-Sayed*, Khalil Elbadri, Alexandra Correia, Hélder A. Santos*, “Polyethylene Glycol-Stabilized Gold Nanostars-Loaded Microneedles for Photothermal Therapy of Melanoma”, Adv. Mater. Technol. 2023, 8(24), 2301159.
414. Huijie Han, Jie Chen, Jiachen Li, Alexandra Correia, Raquel Bártolo, Mohammad-Ali Shahbazi, Tambet Teesalu, Shiqi Wang*, Wenguo Cui*, Hélder A. Santos*, “Enhancing Apoptosome Assembly via Mito-Biomimetic Lipid Nanocarrier for Cancer Therapy”, Adv. Funct. Mater. 2023, 33(46), 2305316.
413. Huijie Han, Jie Chen, Jiachen Li, Alexandra Correia, Raquel Bártolo, Mohammad-Ali Shahbazi, Tambet Teesalu, Shiqi Wang*, Wenguo Cui*, Hélder A. Santos*, “Issue's Back Cover: Enhancing Apoptosome Assembly via Mito-Biomimetic Lipid Nanocarrier for Cancer Therapy (Adv. Funct. Mater. 46/2023)”, Adv. Funct. Mater. 2023, 33(46), 2370275.
412. Han Gao, Shiqi Wang*, Zehua Liu, Jouni T. Hirvonen, Hélder A. Santos*, “Mycophenolic Acid-loaded Naïve Macrophage-derived Extracellular Vesicles Rescue Cardiac Myoblast after Inflammatory Injury”, ACS Appl. Bio Mater. 2023, 6(10), 4269–4276.
411. Jessica Katrine Datsyuk, Keshav Raj Paudel, Rashi Rajput, Sofia Kokkinis, Tammam El Sherkawi, Sachin Kumar Sing, Gaurav Gupta, Dinesh Kumar Chellappan, Stewart Yeung, Philip Michael Hansbro, Brian Gregory George Oliver, Hélder A. Santos, Kamal Dua*, Gabriele De Rubis*, “Emerging Applications and Prospects of NFκB Decoy Oligodeoxynucleotides in Managing Respiratory Diseases”, Chem. Biol. Interact. 2023, 385, 110737.
410. João Ferreira Gil*, Carla Sofia Moura, Vania Silverio, Gil Gonçalves*, Hélder A. Santos*, “Cancer Models on Chip: Paving the Way to Large Scale Trial Applications”, Adv. Mater. 2023, 35(35), 2300692. (Review)
409. Christos Tapeinos*, Giulia Torrieri, Shiqi Wang, João P. Martins, Hélder A. Santos*, “Evaluation of Cell Membrane-Derived Nanoparticles as Therapeutic Carriers for Pancreatic Ductal Adenocarcinoma Using an In Vitro Tumour Stroma Model”, J. Control. Release 2023, 362, 225-242.
408. Giulia Torrieri*, Imran Iqbal, Flavia Fontana, Virpi Talman, Heidi Liljenbäck, Andriana Putri, Wail Nammas, Johan Rajander, Xiang Guo-Li, Philip S. Low, Tambet Teesalu, Anne Roivainen, Jouni Hirvonen, Heikki Ruskoaho, Vimalkumar Balasubramanian*, Antti Saraste*, Hélder A. Santos*, “Macrophage Hitchhiking Nanoparticles for the Treatment of Myocardial Infarction: An In Vitro and In Vivo Study”, Adv. Funct. Mater. 2023, 33(34), 2303658.
407. Giulia Torrieri*, Imran Iqbal, Flavia Fontana, Virpi Talman, Heidi Liljenbäck, Andriana Putri, Wail Nammas, Johan Rajander, Xiang Guo-Li, Philip S. Low, Tambet Teesalu, Anne Roivainen, Jouni Hirvonen, Heikki Ruskoaho, Vimalkumar Balasubramanian*, Antti Saraste*, Hélder A. Santos*, “Macrophage Hitchhiking Nanoparticles for the Treatment of Myocardial Infarction: An In Vitro and In Vivo Study (Adv. Funct. Mater. 34/2023)”, Adv. Funct. Mater. 2023, 33(34), 2370204. (Issue's Inside Front Cover)
406. Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Kiyan Musaie, Saman Rezaei, Mostafa Qahremani, Bo Xiao*, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Emerging Strategies to Bypass Transplant Rejection via Biomaterial-Assisted Immunoengineering: Insights from Islets and Beyond”, Adv. Drug Deliv. Rev. 2023, 200, 115050. (Review)
405. Carmine D'Amico, Flavia Fontana*, Nesma El-Sayed, Khalil Elbadri, Alexandra Correia, Antti Rahikkala, Jukka Saarinen, Mohammad-Ali Shahbazi, Hélder A. Santos*, “Double-Layered Polyvinylpyrrolidone–Poly(Methyl Vinyl Ether-Alt-Maleic Acid) based Microneedles to Deliver Meloxicam: An In Vitro, In Vivo and Short-Term Stability Evaluation Study”, Adv. Ther. 2023, 2300138, 6(8), 2300138.
404. Sandra López Cerdá, Flavia Fontana, Shiqi Wang, Alexandra Correia, Giuseppina Molinaro, Rubén Pareja Tello, Jouni Hirvonen, Christian Celia, Goncalo Barreto, Hélder A. Santos*, “Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid−Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An in Vitro Mechanistic Study”, Adv. Ther. 2023, 2300048, 6(8), 2300048.
403. Maria C. Lobita, Nesma El-Sayed*, João F. Pinto, Hélder A Santos*, “Development of Fast Dissolving Polymer-Based Microneedles for Delivery of an Antigenic Melanoma Cell Membrane”, Int. J. Pharm. 2023, 642, 123143.
402. Ruben Pareja Tello, Shiqi Wang, Flavia Fontana, Alexandra Correia, Giuseppina Molinaro, Sandra Lopez Cerda, Sami Hietala, Jouni Hirvonen, Goncalo Barreto, Hélder A Santos*, “Fabrication of Hydrogel Microspheres via Microfluidics Using Inverse Electron Demand Diels-Alder Click Chemistry-Based Tetrazine-Norbornene for Drug Delivery and Cell Encapsulation Applications”, Biomater. Sci. 2023, 11, 4972-4984.
401. Berta Bosch*, Saliha Moutaharrik*, Andrea Gazzaniga, Kaisa Hiippala, Hélder A. Santos, Alessandra Maroni, Reetta Satokari*, “Development of a Time-Dependent Oral Colon Delivery System of Anaerobic Odoribacter splanchnicus for Bacteriotherapy”, Eur. J. Pharm. Biopharm. 2023, 190, 73-80.
400. Elena Scurti, João Pedro Martins, Christian Celia, Paola Palumbo, Francesca Lombardi, Dalila Iannotta, Luisa Di Marzio*, Hélder A. Santos*, Tapani Viitala*, “In Vitro Characterization and Real-Time Label-Free Assessment of the Interaction of Chitosan-Coated Niosomes with Intestinal Cellular Monolayers”, Langmuir 2023, 39(23), 8255–8266.
399. Mehdi Azizi, Rana Jahanban-Esfahlan, Hadi Samadian, Masoud Hamidi, Khaled Seidi, Alireza Dolatshahi-Pirouz, Amirhossein Ahmadieh Yazdi, Amin Shavandi, Sophie Laurent, Mahsa Be Omide Hagh, Nahid Kasaiyan, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Multifunctional Nanostructures: Intelligent Design to Overcome Biological Barriers”, Mater. Today Bio 2023, 20, 100672.
398. Tiago Carvalho, Raquel Bártolo, Sónia N. Pedro, Bruno F. A. Valente, Ricardo J. B. Pinto, Carla Vilela, Mohammad-Ali Shahbazi, Hélder A. Santos*, Carmen S. R. Freire*, “Injectable Nanocomposite Hydrogels of Gelatin-Hyaluronic Acid Reinforced with Hybrid Lysozyme Nanofibrils-Gold Nanoparticles for the Regeneration of Damaged Myocardium”, ACS Appl. Mater. Interfaces 2023, 15(21), 25860–25872.
397. Pei Zhang, Yingxin Liu, Guobing Feng, Cong Li, Jun Zhou, Chunyang Du, Yuancheng Bai, Shuai Hu, Tianhe Huang, Guan Wang, Peng Quan, Jouni Hirvonen, Jin Fan, Hélder A. Santos*, Dongfei Liu*, “Controlled Interfacial Polymer Self-assembly Coordinates Ultrahigh Drug Loading and Zero-Order Release in Particles Prepared under Continuous Flow”, Adv. Mater. 2023, 35(22), 2211254.
396. Giuseppina Molinaro, Flavia Fontana, Rubén Pareja Tello, Shiqi Wang, Sandra López Cérda, Giulia Torrieri, Alexandra Correia, Eero Waris, Jouni T. Hirvonen, Goncalo Barreto, Hélder A. Santos*, “In Vitro Study of the Anti-inflammatory and Antifibrotic Activity of Tannic Acid-Coated Curcumin-Loaded Nanoparticles in Human Tenocytes”, ACS Appl. Mater. Interfaces 2023, 15(19), 23012–23023.
395. Tomás Bauleth-Ramos, Nesma El-Sayed, Flavia Fontana, Maria Lobita, Mohammad-Ali Shahbazi, Hélder A. Santos*, “Recent Approaches for Enhancing the Performance of Dissolving Microneedles in Drug Delivery Applications”, Mater. Today 2023, 63, 239–287. (Review)
394. Han Gao, Shiqi Wang, Qiang Long, Ruoyu Cheng, Wenhua Lian, Artturi Koivuniemi, Ming Ma, Baoding Zhang, Jouni Hirvonen, Xianming Deng, Zehua Liu*, Xiaofeng Ye*, Hélder A. Santos*, "Rational Design of a Polysaccharide-based Viral Mimicry Nanocomplex for Potent Gene Silencing in Inflammatory Tissues", J. Control. Release 2023, 357, 120–132.
393. Samin Abbaszadeh, Mohammad Reza Eskandari, Vahideh Nosrati-Siahmazgi, Kiyan Musaie, Soraya Mehrabi, Ruikang Tang, Mohammad Reza Jafari, Bo Xiao, Vahid Hosseinpour Sarmadi, Fakhri Haghi, Bo Zhi Chen, Xin Dong Guo*, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “A Photoactive Injectable Antibacterial Hydrogel to Support Chemo-Immunotherapeutic Effect of Antigenic Cell Membrane and Sorafenib by Near-Infrared Light Mediated Tumor Ablation”, Mater. Today Bio 2023, 19, 100609.
392. Chiara Tramontano, João Pedro Martins, Luca De Stefano, Marianna Kemell, Alexandra Correia, Monica Terracciano, Nicola Borbone, Ilaria Rea*, Hélder A. Santos*, “Microfluidic-Assisted Production of Gastro-Resistant Active-Targeted Diatomite Nanoparticles for the Local Release of Galunisertib in Metastatic Colorectal Cancer Cells”, Adv. Healthcare Mater. 2023, 12(6), 2202672.
391. Chiara Tramontano, João Pedro Martins, Luca De Stefano, Marianna Kemell, Alexandra Correia, Monica Terracciano, Nicola Borbone, Ilaria Rea*, Hélder A. Santos*, “Microfluidic-Assisted Production of Gastro-Resistant Active-Targeted Diatomite Nanoparticles for the Local Release of Galunisertib in Metastatic Colorectal Cancer Cells (Adv. Healthcare Mater. 6/2023)”, Adv. Healthcare Mater. 2023, 12(6), 2370029. (Issue's Inside Back Cover)
390. Jialiang Li, Jiqiang Fan, Yan Gao, Shuodan Huang, Di Huang, Jiachen Li, Xiaoyu Wang, Hélder A. Santos*, Pingping Shen*, Bing Xia*, “Porous Silicon Nanocarriers Boost the Immunomodulation of Mitochondria-Targeted Bovine Serum Albumins on Macrophage Polarization”, ACS Nano 2023, 17(2), 1036–1053.
389. Ruoyu Cheng, Shiqi Wang*, Hélder A. Santos*, “Acid-Labile Chemical Bonds-Based Nanoparticles for Endosome Escape and Intracellular Delivery”, Biomed. Technol. 2023, 3, 52–58. (Invited Review)
388. Huijie Han*, Jiachen Li, Hélder A. Santos*, “Recent Advances in Fenton and Fenton-like Reaction Mediated Nanoparticle in Cancer Therapy”, Biomed. Technol. 2023, 3, 40–51. (Invited Review)
387. Hélder A. Santos*, Irina N. Savina*, “Introduction to the RSC Advances themed collection on Nanomaterials in drug delivery”, RSC Advances 2023, 13, 1933–1934. (Editorial)
386. Guest Edited Themed collection on “Nanomaterials in drug delivery”, by Dr. Irina Savina (University of Brighton) and Professor Hélder A. Santos (University of Helsinki, University of Groningen / University Medical Center Groningen).
385. Ruoyu Cheng, Hélder A. Santos*, “Smart Nanoparticle-based Platforms for Regulating Tumor Microenvironment and Cancer Immunotherapy”, Adv. Healthcare Mater. 2023. (in press)
384. Mahsa Sedighi, Zahra Mahmoudi, Alireza Ghasempour, Mehdi Shakibaie, Fahimeh Ghasemi, Mahsa Akbari, Samin Abbaszadeh, Ebrahim Mostafavi*, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Nanostructured Multifunctional Stimuli-Responsive Glycopolypeptide-Based Copolymers for Biomedical Applications”, J. Control. Release 2023, 354, 128–145. (Invited Review)
383. Jiachen Li, Shiqi Wang, Flavia Fontana, Christos Tapeinos, Mohammad-Ali Shahbazi, Huijie Han, Hélder A. Santos*, “Nanoparticles-Based Phototherapy Systems for Cancer Treatment: Current Status and Clinical Potential”, Bioact. Mater. 2023, 23, 471–507.
382. Shu Yang, Fan Wang, Huijie Han, Hélder A. Santos, Yu Zhang, Hongbo Zhang, Jie Wei*, Zhengwei Cai*, “Fabricated Technology of Biomedical Micro-Nano Hydrogel”, Biomed. Technol. 2023, 2, 31–48.
381. Voitto Känkänen*, Micaela Fernandes, Zehua Liu, Jani Seitsonen, Sami-Pekka Hirvonen, Janne Ruokolainen, João F. Pinto, Jouni Hirvonen, Vimalkumar Balasubramanian*, Hélder A. Santos*, “Microfluidic Preparation and Optimization of Sorafenib-Loaded Poly(ethylene glycol-block-caprolactone) Nanoparticles for Cancer Therapy Applications”, J. Colloid Interface Sci. 2023, 633, 383–395.
380. Ruoyu Cheng, Lingxi Jiang, Han Gao, Zehua Liu, Ermei Mäkilä, Shiqi Wang, Qimanguli Saiding, Lei Xiang, Xiaomei Tang, Minmin Shi, Jia Liu, Libin Pang, Jarno Salonen, Jouni Hirvonen, Hongbo Zhang, Wenguo Cui*, Baiyong Shen*, Hélder A. Santos*, “A pH-Responsive Cluster Metal-Organic Framework Nanoparticle for Enhanced Tumor Accumulation and Antitumor Effect”, Adv. Mater. 2022, 34(42), 2203915.
379. Ruoyu Cheng, Lingxi Jiang, Han Gao, Zehua Liu, Ermei Mäkilä, Shiqi Wang, Qimanguli Saiding, Lei Xiang, Xiaomei Tang, Minmin Shi, Jia Liu, Libin Pang, Jarno Salonen, Jouni Hirvonen, Hongbo Zhang, Wenguo Cui*, Baiyong Shen*, Hélder A. Santos*, “A pH-Responsive Cluster Metal–Organic Framework Nanoparticle for Enhanced Tumor Accumulation and Antitumor Effect (Adv. Mater. 42/2022)”, Adv. Mater. 2022, 34(42), 2270290. (Issue's Inside Cover)
378. Monica Terracciano, Flavia Fontana, Andrea Patrizia Falanga, Stefano D’Errico, Giulia Torrieri, Francesca Greco, Chiara Tramontano, Ilaria Rea, Gennaro Piccialli, Luca De Stefano, Giorgia Oliviero, Hélder A. Santos*, Nicola Borbone*, “Development of Surface Chemical Strategies for Synthesising Redox-Responsive Diatomite Nanoparticles as a Green Platform for On-demand Intracellular Release of an Antisense Peptide Nucleic Acid Anticancer Agent”, Small 2022, 18(41), 2204732.
377. Maxim B. Gongalsky*, Daniela A. Muftieva, Jukka K. S. Saarinen, Antti Isomaki, Nikolay V. Pervushin, Gelina S. Kopeina , Leena J. Peltonen, Clare J. Strachan, Boris Zhivotovsky, Hélder A. Santos, Liubov A. Osminkina, “Non-resonant CARS Imaging of Porous and Solid Silicon Nanoparticles in Human Cells”, ACS Biomater. Sci. Eng. 2022, 8(10), 4185–4195.
376. Ruoyu Cheng, Shiqi Wang*, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Jiachen Li, Jouni Hirvonen, Bing Xia, Hélder A. Santos*, “Quantitative Analysis of Porous Silicon Nanoparticles Functionalization by 1H NMR”, ACS Biomater. Sci. Eng. 2022, 8(10), 4132–4139.
375. Christos Tapeinos, Han Gao, Tomás Bauleth-Ramos, Hélder A. Santos*, “Progress in Stimuli-Responsive Biomaterials for Treating Cardiovascular and Cerebrovascular Diseases”, Small 2022, 18(36), 2200291.
374. Zehua Liu, Wenhua Lian, Qiang Long, Ruoyu Cheng, Giulia Torrieri, Baoding Zhang, Artturi Koivuniemi, Mohammad Mahmoudzadeh, Alex Bunker, Han Gao, Hongbin He, Yun Chen, Jouni Hirvonen, Rongbin Zhou, Qiang Zhao*, Xiaofeng Ye*, Xianming Deng*, Hélder A. Santos*, “Front Cover Image: Promoting Cardiac Repair through Simple Engineering of Nanoparticles with Exclusive Targeting Capability toward Myocardial Reperfusion Injury by Thermal Resistant Microfluidic Platform (Adv. Funct. Mater. 36/2022)”, Adv. Funct. Mater. 2022, 32(36), 2270201.
373. Nuria Lafuente-Gómez*, Shiqi Wang, Flavia Fontana, Mónica Dhanjani, David García-Soriano, Alexandra Correia, Milagros Castellanos, Ciro Rodriguez Diaz, Gorka Salas, Hélder A. Santos*, Álvaro Somoza*, “Synergistic Immunomodulatory Effect in Macrophages Mediated by Magnetic Nanoparticles Modified with miRNAs”, Nanoscale 2022, 14(31), 11129-11138.
372. Zehua Liu, Wenhua Lian, Qiang Long, Ruoyu Cheng, Giulia Torrieri, Baoding Zhang, Artturi Koivuniemi, Mohammad Mahmoudzadeh, Alex Bunker, Han Gao, Hongbin He, Yun Chen, Jouni Hirvonen, Rongbin Zhou, Qiang Zhao*, Xiaofeng Ye*, Xianming Deng*, Hélder A. Santos*, “Promoting Cardiac Repair Through Simple Engineering of Nanoparticles With Exclusive Targeting Capability Towards Myocardial Reperfusion Injury by Thermal Resistant Microfluidic Platform”, Adv. Funct. Mater. 2022, 32(36), 2204666.
371. Zhenyang Wei, Shiqi Wang, Jouni Hirvonen, Hélder A. Santos*, Wei Li*, “Microfluidics Fabrication of Micrometer-Sized Hydrogels With Precisely Controlled Geometries for Biomedical Applications”, Adv. Healthcare Mater. 2022, 11(16), 2200846. (Review)
370. Qiang Long, Zehua Liu, Qianwen Shao, Hongpeng Shi, Shixing Huang, Chenyu Jiang, Bei Qian, Yiming Zhong, Xiaojun He, Xiaogang Xiang, Yang Yang, Bing Li, Xiaoxiang Yan, Qiang Zhao*, Xiaoli Wei*, Hélder A. Santos*, Xiaofeng Ye*, “Autologous Skin Fibroblast-Based PLGA Nanoparticles for Treating Multiorgan Fibrosis”, Adv. Sci. 2022, 9(21), 2200856.
369. Mohammad Khedri, Fatemeh Afsharchi, Amirhosein Hasanpour Souderjani, Sima Rezvantalab*, Mohsen Didandeh, Reza Maleki, Kiyan Musaie, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Molecular Scale Study on the Interactions of Biocompatible Nanoparticles With Macrophage Membrane and Blood Proteins”, Nano Select 2022, 3(8), 1252-1263.
368. Ana Sara Gomes, Alexandra Correia, Antti Rahikkala, Ermei Mäkilä, Madalena M. Pinto, Emília Sousa, Jarno Salonen, Lucília Saraiva, Hélder A. Santos*, “Folic Acid-Mesoporous Silicon Nanoparticles Enhance the Anticancer Activity of the p73-Activating Small Molecule LEM2”, Int. J. Pharm. 2022, 624, 121959.
367. Mohammad Khedri, Nima Beheshtizadeh, Mohammadreza Rostami, Ali Sufali, Sima Rezvantalab, Mohammad Dahri, Reza Maleki*, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Artificial Intelligence Deep Exploration of Influential Parameters on Physicochemical Properties of Curcumin-Loaded Electrospun Nanofibers”, Adv. NanoBiomed Res. 2022, 2(6), 2100143.
366. Tiago Carvalho, Nazanin Zanjanizadeh Ezazi, Alexandra Correia, Carla Vilela, Hélder A. Santos*, Carmen S. R. Freire*, “Gelatin-Lysozyme Nanofibrils Electrospun Patches with Improved Mechanical, Antioxidant and Bioresorbability Properties for Myocardial Regeneration Applications”, Adv. Funct. Mater. 2022, 32(21), 2113390.
365. Mohammad Khedri, Reza Maleki, Mohammad Dahri, Mohammad Moein Sadeghi, Sima Rezvantalab*, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Engineering of 2D Nanomaterials to Trap and Kill SARS-CoV-2: A New Insight From Multi-microsecond Atomistic Simulations”, Drug Deliv. Transl. Res. 2022, 12(6), 1408–1422.
364. Alexander J. Najibi, Maxence O. Dellacherie, Ting-Yu Shih, Edward J. Doherty, Des A. White, Tomás Bauleth-Ramos, Alexander G. Stafford, James C. Weaver, Chyenne D. Yeager, Benjamin T. Seiler, Matthew Pezone, Aileen W. Li, Bruno Sarmento, Hélder A. Santos, David J. Mooney*, Luo Gu*, “Scaffold Vaccines for Generating Robust and Tunable Antibody Responses”, Adv. Funct. Mater. 2022, 32(16), 2110905.
363. MeltemAvci-Adali*, Hélder A. Santos*, “Current Trends in Delivery of Non-Viral Nucleic Acid-Based Therapeutics for Improved Efficacy”, Adv. Drug Deliv. Rev. 2022, 185, 114297. (Editorial)
362. Ruoyu Cheng, Hélder A. Santos*, “Inhaled hydrogel-based microspheres for management of COVID-19: A new sweeper biological platform”, Matter 2022, 5(4), 1065-1067.
361. Xiaohui Mou, Hongbo Zhang, Hua Qiu, Wentai Zhang, Ying Wang, Kaiqin Xiong, Nan Huang*, Hélder A. Santos*, Zhilu Yang*, “Mussel-Inspired and Bioclickable Peptide Engineered Surface to Combat Thrombosis and Infection”, Res. 2022, 2022, 9780879.
360. Wei Li, Jian Chen, Shujie Zhao, Tianhe Huang, Huiyan Ying, Claudia Trujillo, Giuseppina Molinaro, Zheng Zhou, Tao Jiang, Wei Liu, Linwei Li, Yuancheng Bai, Peng Quan, Yaping Ding, Jouni Hirvonen, Guoyong Yin*, Hélder A. Santos*, Jin Fan*, Dongfei Liu*, “High Drug-Loaded Microspheres Enabled by Controlled in-Droplet Precipitation Promote Functional Recovery After Spinal Cord Injury”, Nature Commun. 2022, 13, 1262.
359. Pei Zhang, Chunyang Du, Tianhe Huang, Shuai Hu, Yuancheng Bai, Cong Li, Guobing Feng, Yue Gao, Zhi Li, Baoxun Wang, Jouni T. Hirvonen, Jin Fan, Hélder A. Santos*, Dongfei Liu*, “Surface Adsorption-Mediated Ultrahigh Efficient Peptide Encapsulation with a Precise Ratiometric Control for Type 1 and 2 Diabetic Therapy”, Small 2022, 18(15), 2200449.
358. Jiachen Li, Di Huang, Ruoyu Cheng, Patrícia Figueiredo, Flavia Fontana, Alexandra Correia, Shiqi Wang, Zehua Liu, Marianna Kemell, Giulia Torrieri, Ermei M. Mäkilä, Jarno J. Salonen, Jouni Hirvonen, Yan Gao, Jialiang Li, Zhenyang Luo*, Hélder A. Santos*, Bing Xia*, “Multifunctional Biomimetic Nanovaccines Based on Photothermal and Weak-Immunostimulatory Nanoparticulate Cores for the Immunotherapy of Solid Tumors”, Adv. Mater. 2022, 34(9), 2108012.
357. Jiachen Li, Di Huang, Ruoyu Cheng, Patrícia Figueiredo, Flavia Fontana, Alexandra Correia, Shiqi Wang, Zehua Liu, Marianna Kemell, Giulia Torrieri, Ermei M. Mäkilä, Jarno J. Salonen, Jouni Hirvonen, Yan Gao, Jialiang Li, Zhenyang Luo*, Hélder A. Santos*, Bing Xia*, “Multifunctional Biomimetic Nanovaccines Based on Photothermal and Weak-Immunostimulatory Nanoparticulate Cores for the Immunotherapy of Solid Tumors (Adv. Mater. 9/2022)”, Adv. Mater. 2022, 34(9), 2270074. (Issue's Back Cover Page)
356. Wenguo Cui, Hélder A. Santos, Boyang Zhang, Y. Shrike Zhang, “Functional Biomaterials”, APL Bioeng. 2022, 6, 010401. (Editorial, invited)
355. Giulia Torrieri, Mónica P. A. Ferreira, Mohammad-Ali Shahbazi, Virpi Talman, S. Tuuli Karhu, Lotta Pohjolainen, Cláudia Carvalho, João F. Pinto, Jouni Hirvonen, Heikki Ruskoaho, Vimalkumar Balasubramanian*, Hélder A. Santos*, “In Vitro Evaluation of the Therapeutic Effects of Dual-Drug Loaded Spermine-Acetalated Dextran Nanoparticles Coated With Tannic Acid for Cardiac Applications”, Adv. Funct. Mater. 2022, 32(5), 2109032.
354. Huijie Han, Raquel Bártolo, Jiachen Li, Mohammad-Ali Shahbazi*, Hélder A. Santos*, “Biomimetic Platelet Membrane-Coated Nanoparticles for Targeted Therapy”, Eur J. Pharm. Biopharm. 2022, 172, Pages 1-15. (Invited Review)
353. Yuntao Liu, Siqi Zeng, Wei Ji, Huan Yao, Lin Lin*, Haiying Cui, Hélder A. Santos*, Guoqing Pan*, “Emerging Theranostic Nanomaterials in Diabetes and Its Complications”, Adv. Sci. 2022, 9(3), 2102466. (Review)
352. Jiahui Zhang, Cheng Ji, Hongbo Zhang, Hui Shi, Fei Mao, Hui Qian, Wenrong Xu, Dongqing Wang, Jianming Pan, Xinjian Fang*, Hélder A. Santos*, Xu Zhang*, “Engineered Neutrophil-Derived Exosome-like Vesicles for Targeted Cancer Therapy”, Sci. Adv. 2022, 8(2), eabj8207. (Issue's Front Cover Page)
351. João P. Martins*, Patrícia Figueiredo, Shiqi Wang, Erika Espo, Elena Celi, Beatriz Martins, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Mauri A. Kostiainen, Christian Celia, Vincenzo Cerullo, Tapani Viitala, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Neonatal Fc Receptor-Targeted Lignin-Encapsulated Porous Silicon Nanoparticles for Enhanced Cellular Interactions and Insulin Permeation Across the Intestinal Epithelium”, Bioact. Mater. 2022, 9, 299-315.
350. Muhammad Nadeem Hafeez, Nicola d’Avanzo, Valentina Russo, Luisa Di Marzio, Felisa Cilurzo, Donatella Paolino, Massimo Fresta, Barbara Barboni, Hélder A. Santos*, Christian Celia*, “Tendon Tissue Repair in Prospective of Drug Delivery, Regenerative Medicines and Innovative Bio-scaffolds”, Stem Cells Int. 2021, 1488829. (Review)
349. Iris Seitz, Ahmed Shaukat, Kurt Nurmi, Heini Ijäs, Jouni Hirvonen, Hélder A. Santos, Mauri A. Kostiainen*, Veikko Linko*, “Prospective Cancer Therapies Using Stimuli-Responsive DNA Nanostructures”, Macromol. Biosci. 2021, 21(12), 2100272. (Review)
348. Pei Zhang, Cong Li, Tianhe Huang, Yuancheng Bai, Peng Quan, Wei Li, Zifan Zhang, Feng Zhang, Zehua Liu, Bowen Wan, Alexandra Correia, Jie Zhang, Xuri Wu, Jouni T. Hirvonen, Hélder A. Santos, Jin Fan, Ting Cai, Dongfei Liu*, “Inhibiting Phase Transfer of Protein Nanoparticles by Surface Camouflage - A Versatile and Efficient Protein Encapsulation Strategy”, Nano Lett. 2021, 21(22), 9458–9467.
347. Ilaria Arduino, Zehua Liu, Rosa Maria Iacobazzi, Angela Assunta Lopedota, Antonio Lopalco, Annalisa Cutrignelli, Valentino Laquintana, Letizia Porcelli, Amalia Azzariti, Massimo Franco, Hélder A. Santos*, Nunzio Denora*, “Microfluidic preparation and in vitro evaluation of iRGD-functionalized solid lipid nanoparticles for targeted delivery of paclitaxel to tumor cells”, Int. J. Pharm. 2021, 610, 121246.
346. Gabriela Guedes, Shiqi Wang*, Flavia Fontana, Patrícia Figueiredo, Jere Lindén, Alexandra Correia, Ricardo J. B. Pinto, Sami Hietala, Filipa L. Sousa, Hélder A. Santos*, “Dual-Crosslinked Dynamic Hydrogel Incorporating {Mo154} with pH and NIR Responsiveness for Chemo-Photothermal Therapy”, Adv. Mater. 2021, 33(40), 2007761.
345. Gabriela Guedes, Shiqi Wang*, Flavia Fontana, Patrícia Figueiredo, Jere Lindén, Alexandra Correia, Ricardo J. B. Pinto, Sami Hietala, Filipa L. Sousa, Hélder A. Santos*, “Front Cover Picture: Dual-Crosslinked Dynamic Hydrogel Incorporating {Mo154} with pH and NIR Responsiveness for Chemo-Photothermal Therap (Adv. Mater. 40/2021)”, Adv. Mater. 2021, 33(40), 2170311.
344. Patrícia Figueiredo*, Anni Lepland, Pablo Scodeller*, Flavia Fontana, Giulia Torrieri, Mattia Tiboni, Mohammad‐Ali Shahbazi, Luca Casettari, Mauri A. Kostiainen, Jouni Hirvonen, Tambet Teesalu*, Hélder A. Santos*, “Peptide-Guided Resiquimod-Loaded Lignin Nanoparticles Convert Tumor-Associated Macrophages from M2 to M1 Phenotype for Enhanced Chemotherapy”, Acta Biomater. 2021, 2021, 133, 231-243.
343. Cláudio Ferro, Helena F. Florindo*, Hélder A. Santos*, “Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics”, Adv. Healthcare Mater. 2021, 10(16), 2100598. (Invited Review)
342. Huanhuan Luo, Li Kong, Feng Zhang, Chenglong Huang, Jiayi Chen, Hongbo Zhang, Han Yu, Song Zheng, Hongwei Xu, Yiran Zhang, Lianfu Deng, Gang Chen*, Hélder A. Santos*, Wenguo Cui*, “Light-Controlled Nanosystem With Size Flexibility Improves Targeted Retention for Tumor Suppression”, Adv. Funct. Mater. 2021, 31(27), 2101262.
341. Huanhuan Luo, Li Kong, Feng Zhang, Chenglong Huang, Jiayi Chen, Hongbo Zhang, Han Yu, Song Zheng, Hongwei Xu, Yiran Zhang, Lianfu Deng, Gang Chen*, Hélder A. Santos*, Wenguo Cui*, “Front Cover: Light-Controlled Nanosystem With Size Flexibility Improves Targeted Retention for Tumor Suppression (Adv. Funct. Mater. 27/2021)”, Adv. Funct. Mater. 2021, 31(27), 2170192. (Issue's inside Front Cover Page)
340. Han Gao, Ruoyu Cheng, Hélder A. Santos*, “Nanoparticle-Mediated siRNA Delivery Systems for Cancer Therapy”, VIEW 2021, 2(3), 20200111. (Invited Mini-Review)
339. Cláudia Azevedo, Soraia Pinto, Sopisa Benjakul, Jeannette Nilsen, Hélder A. Santos, Giovanni Traverso, Jan Terje Andersen*, Bruno Sarmento*, “Prevention of Diabetes-Associated Fibrosis: Strategies in FcRn-targeted Nanosystems for Oral Drug Delivery”, Adv. Drug. Deliv. Rev. 2021, 175, 113778. (Invited Review)
338. Zehua Liu, Shiqi Wang, Christos Tapeinos, Giulia Torrieri, Voitto Känkänen, Nesma El-Sayed, Andre Python, Jouni T. Hirvonen, Hélder A. Santos*, “Non-Viral Nanoparticles for RNA Interference: Principles of Design and Practical Guidelines”, Adv. Drug Deliv. Rev. 2021, 174, 576-612 (Invited Review)
337. Feng Zhang, Yiran Zhang, Li Kong, Huanhuan Luo, Yuezhou Zhang, Ermei Mäkilä, Jarno Salonen, Jouni T. Hirvonen, Yueqi Zhu, Yingsheng Cheng, Lianfu Deng, Hongbo Zhang*, Alexander Kros, Wenguo Cui*, Hélder A. Santos*, “Multistage Signal Interactive Nanoparticles Improves Tumor Targeting Through Efficient Nanoparticle-Cell Communications”, Cell Rep. 2021, 35(8), 109131. (Issue's Inside Front Cover Page)
336. Surachet Imlimthan, You Cheng Khng, Outi Keinänen, Wenzhong Zhang, Anu J. Airaksinen, Mauri A. Kostiainen, Brian M. Zeglis, Hélder A. Santos, Mirkka Sarparanta*, “A Theranostic Cellulose Nanocrystal-based Drug Delivery System with Enhanced Retention in Pulmonary Metastasis of Melanoma”, Small 2021, 17(18), 2007705.
335. Zhijie Chen, Feng Zhang, Hongbo Zhang, Liang Cheng, Kaizhe Chen, Jieliang Shen, Jin Qi, Lianfu Deng, Chuan He*, Hélder A. Santos*, Wenguo Cui*, “DNA-Grafted Hyaluronic Acid System with Enhanced Injectability and Biostability for Photo-Controlled Osteoarthritis Gene Therapy”, Adv. Sci. 2021, 8(9), 2004793.
334. Shiqi Wang, Flavia Fontana, Mohammad-Ali Shahbazi, Hélder A. Santos*, “Acetalated Dextran Based Nano- and Microparticles: Synthesis, Fabrication, and Therapeutic Applications”, Chem. Commun. 2021, 57(35), 4212–4229. (Invited Featured Article)
333. Shiqi Wang, Flavia Fontana, Mohammad-Ali Shahbazi, Hélder A. Santos*, “Front Cover: Acetalated Dextran Based Nano- and Microparticles: Synthesis, Fabrication, and Therapeutic Applications”, ChemComm. 2021, 57(35), 4201–4201. (Invited Front Cover)
332. Leila Pourtalebi Jahromi, Mohammad-Ali Shahbazi*, Aziz Maleki, Amir Azadi*, Hélder A. Santos*, “Chemically Engineered Immune Cell-Derived Microrobots and Biomimetic Nanoparticles: Emerging Biodiagnostic and Therapeutic Tools”, Adv. Sci. 2021, 8(8), 2002499. (Review)
331. Haibei Tong, Yan Gao, Jialiang Li, Jiachen Li, Di Huang, Jisen Shi*, Hélder A. Santos*, and Bing Xia*, “Mitochondria-Targeted Bovine Serum Albumin @ Copper Sulfide Nanocomposites Conjugated with Rhodamine-110 dye for an Enhanced Efficacy of Cancer Photothermal Therapy”, Part. Part. Syst. Charact. 2021, 38(4), 2100013.
330. Flavia Fontana, Patrícia Figueiredo, João P. Martins, Hélder A. Santos*, “Requirement for Animal Experiments: Problems and Challenges”, Small 2021, 17(15), 2004182. (Invited paper for Special Issue: Advanced In Vitro Models for Replacement of Animal Experiments)
329. Xu Zhang*, Hongbo Zhang, Jianmei Gu, Jiayin Zhang, Hui Shi, Hui Qian, Dongqing Wang, Wenrong Xu, Jianming Pan*, Hélder A. Santos*, “Engineered Extracellular Vesicles for Cancer Therapy”, Adv. Mater. 2021, 33(14), 2005709. (Review)
328. Carmine D’Amico, Flavia Fontana, Ruoyu Cheng, Hélder A. Santos*, “Development of Vaccine Formulations: Past, Present and Future”, Drug Deliv. Transl. Res. 2021, 11(2), 353–372. (Invited Review)
327. Yaping Ding*, Wei Li, Dirk W. Schubert, Aldo R. Boccaccini, Judith A. Roether*, Hélder A. Santos*, “An Organic-inorganic Hybrid Scaffold with Honeycomb-like Structures Enabled by One-step Self-assembly-driven Electrospinning”, Mater. Sci. Eng. C 2021, 124, 112079.
326. Lu Chen, Liucheng Zhang, Hongbo Zhang, Xiaoming Sun, Dan Liu, Jianming Zhang, Yuguang Zhang*, Liying Cheng*, Hélder A. Santos*, Wenguo Cui*, “Programmable Immune Activating Electrospun Fibers for Skin Regeneration”, Bioact. Mater. 2021, 6(10), 3218-3230.
325. Qiaolin Wei, Hamed Arami, Hélder A. Santos, Hongbo Zhang, Yangyang Li, Jian He, Danni Zhong, Daishun Ling, and Min Zhou*, “Intraoperative Assessment and Photothermal Ablation of the Tumor Margins Using Gold Nanoparticles”, Adv. Sci. 2021, 8(5), 2002788.
324. Zhi Qu, Kuan Yau Wong, Md. Moniruzzaman, Jakob Begun, Hélder A. Santos, Sumaira Z. Hasnain, Tushar Kumeria, Michael A. McGuckin, Amirali Popat*, “One-Pot Synthesis of pH-Responsive Eudragit®-Mesoporous Silica Nanocomposites Enable Colonic Delivery of Glucocorticoids for the Treatment of Inflammatory Bowel Disease”, Adv. Ther. 2021, 4(2), 2000165.
323. Nicola d’Avanzo, Giulia Torrieri, Patrícia Figueiredo, Christian Celia, Donatella Paolino, Alexandra Correia, Karina Moslova, Tambet Teesalu, Massimo Fresta*, Hélder A. Santos*, “LinTT1 Peptide-Functionalized Liposomes for Targeted Breast Cancer Therapy”, Int. J. Pharm. 2021, 597, 120346.
322. Fatemeh Poustchi, Hamed Amani, Zainab Ahmadian, Seyyed Vahid Niknezhad, Soraya Mehrabi, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Combination Therapy of Killing Diseases by Injectable Hydrogels: From Concept to Medical Applications”, Adv. Healthcare Mater. 2021, 10(3), 2001571. (Review)
321. Zainab Ahmadian, Alexandra Correia, Masoud Hasany, Patrícia Figueiredo, Faramarz Dobakhti, Mohammad Reza Eskandari, Seyed Hojjat Hosseini, Ramin Abiri, Shiva Khorshid, Jouni Hirvonen, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “A Hydrogen-Bonded Extracellular Matrix-Mimicking Bactericidal Hydrogel with Radical Scavenging and Hemostatic Function for pH-Responsive Wound Healing Acceleration”, Adv. Healthcare Mater. 2021,10(3), 2001122.
320. Zainab Ahmadian, Alexandra Correia, Masoud Hasany, Patrícia Figueiredo, Faramarz Dobakhti, Mohammad Reza Eskandari, Seyed Hojjat Hosseini, Ramin Abiri, Shiva Khorshid, Jouni Hirvonen, Hélder A. Santos*, Mohammad-Ali Shahbazi*, “Anti‐Bacterial Hydrogels: A Hydrogen‐Bonded Extracellular Matrix‐Mimicking Bactericidal Hydrogel with Radical Scavenging and Hemostatic Function for pH‐Responsive Wound Healing Acceleration (Adv. Healthcare Mater. 3/2021)”, Adv. Healthcare Mater. 2021,10(3), 2170009. (Issue's inside Front Cover Page)
319. Ilaria Arduino, Zehua Liu, Antti Rahikkala, Patrícia Figueiredo, Alexandra Correia, Annalisa Cutrignelli, Nunzio Denora*, Hélder A. Santos*, “Preparation of Cetyl Palmitate-based PEGylated Solid Lipid Nanoparticles by Microfluidic Technique”, Acta Biomater. 2021, 121, 566–578.
318. Shiqi Wang, Saowanee Wannasarit, Patrícia Figueiredo, Giuseppina Molinaro, Yaping Ding, Alexandra Correia, Luca Casettari, Ruedeekorn Wiwattanapatapee, Jouni Hirvonen, Dongfei Liu, Wei Li*, Hélder A. Santos*, “Intracellular Delivery of Budesonide and Polydopamine Co-loaded in Endosomolytic Poly(Butyl Methacrylate-co-Methacrylic Acid) Grafted Acetalated Dextran for Macrophage Phenotype Switch From M1 to M2”, Adv. Ther. 2021, 4(1), 2000058. (Invited Full Paper for Special Issue on "Advanced Nanosystems for Clinical Translation", Guest-edited by Profs. Hélder Santos, Christian Celia, and Donatella Paolino)
317. Christian Celia*, Donatella Paolino*, Hélder A. Santos*, “Advanced Nanosystems for Clinical Translation”, Adv. Ther. 2021, 4(1), 2000215. (Guest Editorial for Special Issue on "Advanced Nanosystems for Clinical Translation", Guest-edited by Profs. Hélder Santos, Christian Celia, and Donatella Paolino)
316. Shahla Karimzadeh, Siamak Javanbakht, Behzad Baradaran, Mohammad-Ali Shahbazi, Mahmoud Hashemzaei, Ahad Mokhtarzadeh*, Hélder A. Santos*, “Synthesis and Therapeutic Potential of Stimuli-responsive Metal-Organic Frameworks”, Chem. Eng. J. 2021, 408, 127233. (Review)
315. Clarinda Costa, Zehua Liu, Sandra Simões, Alexandra Correia, Antti Rahikkala, Jani Seitsonen, Janne Ruokolainen, Ana Aguiar-Ricardo*, Hélder A. Santos, M. Luísa Corvo*, “One-Step Microfluidics Production of Enzyme-Loaded Liposomes for the Treatment of Inflammatory Diseases”, Colloids Surf. B: Biointerfaces 2021, 199, 111556.
314. Hamed Amani, Mohammad-Ali Shahbazi*, Carmine D'Amico, Flavia Fontana, Samin Abbaszadeh, Hélder A. Santos*, “Microneedles for Painless Transdermal Immunotherapeutic Applications”, J. Control. Release 2021, 330, 185–217. (Review)
313. Hamed Amani, Mohammad-Ali Shahbazi*, Carmine D'Amico, Flavia Fontana, Samin Abbaszadeh, Hélder A. Santos*, “Microneedles for Painless Transdermal Immunotherapeutic Applications”, J. Control. Release 2021, 330. (Issue's inside Front Cover Page)
312. Dave Lumen, Shiqi Wang, Ermei Mäkilä, Surachet Imlimthan, Mirkka Sarparanta, Alexandra Correia, Christina Westerveld Haug, Jouni Hirvonen, Hélder A. Santos*, Anu J. Airaksinen*, Werner Filtvedt*, Jarno Salonen*, “Investigation of Silicon Nanoparticles Produced by Centrifuge Chemical Vapor Deposition for Applications in Therapy and Diagnostics”, Eur. J. Pharm. Biopharm. 2021, 158, 254–265.
311. Nuno Vale*, Diana Duarte, Alexandra Correia, Cláudia Alves, Patrícia Figueiredo, Hélder A. Santos, “New Insights into Ethionamide Metabolism: Influence of Oxidized Methionine on its Degradation Path”, RSC Med. Chem. 2020, 11(12), 1423–1428.
310. Youssof Sefidi-Heris, Abolfazl Jahangiri, Ahad Mokhtarzadeh*, Mohammad-Ali Shahbazi*, Saeed Khalili, Behzad Baradaran, Jafar Mosafer, Amir Baghbanzadeh, Maryam Hejazi, Mahmoud Hashemzaei, Michael R Hamblin*, Hélder A. Santos*, “Recent Progress in the Design of DNA Vaccines Against Tuberculosis”, Drug Discov. Today 2020, 25(11), 1971–1987. (Review)
309. Ruoyu Cheng, Flavia Fontana, Junyuan Xiao, Zehua Liu, Patrícia Figueiredo, Mohammad-Ali Shahbazi, Shiqi Wang, Jing Jin, Giulia Torrieri, Jouni T. Hirvonen, Hongbo Zhang, Tongtong Chen, Wenguo Cui*, Yong Lu*, Hélder A. Santos*, “Recombination Monophosphoryl Lipid A Derived Vacosome for the Development of Preventive Cancer Vaccines”, ACS Appl. Mater. Interfaces 2020, 12(40), 44554–44562.
308. Voitto Känkänen, Jani Seitsonen, Henri Tuovinen, Janne Ruokolainen, Jouni Hirvonen, Vimalkumar Balasubramanian*, Hélder A. Santos*, “Evaluation of the Effects of Nanoprecipitation Process Parameters on the Size and Morphology of Poly(ethylene oxide)-block-Polycaprolactone Nanostructures”, Int. J. Pharm. 2020, 590, 119900.
307. Antti Rahikkala*, Flavia Fontana, Tomás Bauleth-Ramos, Alexandra Correia, Marianna Kemell, Jani Seitsonen, Ermei Mäkilä, Bruno Sarmento, Jarno Salonen, Janne Ruokolainen, Jouni Hirvonen, Hélder A. Santos*, “Hybrid Red Blood Cell Membrane Coated Porous Silicon Nanoparticles Functionalized with Cancer Antigen Induce Depletion of T Cells”, RSC Adv. 2020, 10(10), 35198–35205.
306. Hanna Viisanen, Ulpukka Nuotio, Oleg Kambur, Arun Kumar Mahato, Viljami Jokinen, Tuomas Lilius, Wei Li, Hélder A. Santos, Mati Karelson, Pekka Rauhala, Eija Kalso, Yulia A. Sidorova*, “Novel RET Agonist for the Treatment of Experimental Neuropathies”, Mol. Pain 2020, 16, 1–19.
305. Afsoon Farzan, Sedigheh Borandeh, Nazanin Zanjanizadeh Ezazi, Sami Lipponen, Hélder A. Santos, Jukka Seppälä*, “3D Scaffolding of Fast Photocurable Polyurethane for Soft Tissue Engineering by Stereolithography: Influence of Materials and Geometry on Growth of Fibroblast Cells”, Eur. Polym. J. 2020, 139, 109988.
304. Flavia Fontana*, Hanna Lindstedt, Alexandra Correia, Jacopo Chiaro, Otto K. Kari, Joseph Ndika, Harri Alenius, Jonas Buck, Sandro Sieber, Ermei Mäkilä, Jarno Salonen, Arto Urtti, Vincenzo Cerullo, Jouni T. Hirvonen, Hélder A. Santos*, “Influence of Cell Membrane Wrapping on the Cell-Porous Silicon Nanoparticle Interactions”, Adv. Healthcare Mater. 2020, 9(17), 2000529.
303. Flavia Fontana*, Hanna Lindstedt, Alexandra Correia, Jacopo Chiaro, Otto K. Kari, Joseph Ndika, Harri Alenius, Jonas Buck, Sandro Sieber, Ermei Mäkilä, Jarno Salonen, Arto Urtti, Vincenzo Cerullo, Jouni T. Hirvonen, Hélder A. Santos*, “Cell Membrane Wrapping: Influence of Cell Membrane Wrapping on the Cell−Porous Silicon Nanoparticle Interactions (Adv. Healthcare Mater. 17/2020)”, Adv. Healthcare Mater. 2020, 9(17), 2070056. (Issue's Front Cover Page)
302. Rubina Ajdary, Nazanin Zanjanizadeh Ezazi, Alexandra Correia, Marianna Kemell, Siqi Huan, Heikki J. Ruskoaho, Jouni Hirvonen, Hélder A. Santos*, Orlando J. Rojas*, “Multifunctional 3D-Printed Patches for Long-Term Drug Release Therapies After Myocardial Infarction”, Adv. Funct. Mater. 2020, 30(34), 2003440.
301. Ling Wang, Nazanin Zanjanizadeh Ezazi, Liang Liu, Rubina Ajdary, Wenchao Xiang, Maryam Borghei, Hélder A. Santos, Orlando J. Rojas*, “Microfibers Synthesized by Wet-Spinning of Chitin Nanomaterials: Mechanical, Structural and Cell Proliferation Properties”, RSC Adv. 2020, 10, 29450–29459.
300. Yunzhan Li, Zehua Liu, Li Li, Wenhua Lian, Yaohui He, Khalil Elbadry, Ermei Mäkilä, Wenzhong Zhang, Giulia Torrieri, Xueyan Liu, Jingyi Su, Yuanming Xiu, Flavia Fontana, Jarno Salonen, Jouni Hirvonen, Wen Liu, Hongbo Zhang*, Hélder A. Santos*, Xianming Deng*, “Tandem-Mass-Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses Under Diseased Condition”, Adv. Sci. 2020, 7(15), 2001129.
299. Nadia Fattahi, Mohammad-Ali Shahbazi*, Aziz Maleki, Mehrdad Hamidi*, Ali Ramazani, Hélder A. Santos*, “Emerging Insights on Drug Delivery by Fatty Acid Mediated Synthesis of Lipophilic Prodrugs as Novel Nanomedicines”, J. Control. Release 2020, 326, 556–598. (Review)
298. Yang Ye, Jian He, Yue Qiao, Yuchen Qi, Hongbo Zhang, Hélder A. Santos, Danni Zhong, Wanlin Li, Shiyuan Hua, Wei Wang, Andrzej Grzybowski, Ke Yao*, Min Zhou*, “Mild Temperature Photothermal Assisted Anti-Bacterial and Anti-Inflammatory Nanosystem for Synergistic Treatment of Post-Cataract Surgery Endophthalmitis”, Theranostics 2020, 10(19), 8541–8557.
297. Aziz Maleki*, Mohammad-Ali Shahbazi, Vajiheh Alinezhad, Hélder A. Santos*, “The Progress and Prospect of Zeolitic Imidazolate Frameworks in Cancer Therapy, Antibacterial Activity, and Biomineralization”, Adv. Healthcare Mater. 2020, 9(12), 2000248. (Review)
296. Clarinda Costa, Zehua Liu, João P. Martins, Alexandra Correia, Patrícia Figueiredo, Antti Rahikkala, Wei Li, Jani Seitsonen, Janne Ruokolainen, Sami-Pekka Hirvonen, Ana Aguiar-Ricardo, Luísa Corvo*, Hélder A. Santos*, “All-in-One Microfluidic Assembly of Insulin-Loaded pH-Responsive Nano-in-Microparticles For Oral Insulin Delivery”, Biomater. Sci. 2020, 8, 3270–3277.
295. Gabriela Guedes, Shiqi Wang, Hélder A. Santos, Filipa L. Sousa*, “Polyoxometalate Composites in Cancer Therapy and Diagnostic”, Eur. J. Inorg. Chem. 2020, 2020 (22), 2121–2132. (Invited Review)
294. Shiqi Wang, Saowanee Wannasarit, Patrícia Figueiredo, Jiachen Li, Alexandra Correia, Bing Xia, Ruedeekorn Wiwattanapatapee, Jouni Hirvonen, Dongfei Liu, Wei Li*, Hélder A. Santos*, “Superfast and Controllable Microfluidic Inking of Anti-Inflammatory Melanin-like Nanoparticles Inspired by Cephalopod”, Mater. Horiz. 2020, 7, 1573–1580.
293. Antti Rahikkala, Hélder A. Santos, “Kohdennetut Nanolääkkeet Voivat Muokata Tulevaisuuden Terveydenhoitoa”, Duodecim 2020, 136(11), 1318–1325.
292. Daulat Haleem Khan, Sajid Bashir, Muhammad Imran Khan, Patrícia Figueiredo, Hélder A. Santos, Leena Peltonen*, “Formulation Optimization and In Vitro Characterization of Rifampicin and Ceftriaxone Dual Drug Loaded Niosomes With High Energy Probe Sonication Technique”, J. Drug Deliv. Sci. Technol. 2020, 58, 101763.
291. João Pedro Martins, José das Neves, María de la Fuente, Christian Celia, Helena Florindo, Nazende Günday-Türeli, Amirali Popat, José Luis Santos, Flávia Sousa, Ruth Schmid, Joy Wolfram, Bruno Sarmento, Hélder A. Santos*, “The Solid Progress of Nanomedicine”, Drug Deliv. Transl. Res. 2020, 10, 726–729. (Invited commentary)
290. Tomás Bauleth‐Ramos*, Tália Feijão, André Gonçalves, Mohammad‐Ali Shahbazi, Zehua Liu, Cristina Barrias, Maria José Oliveira, Pedro Granja, Hélder A. Santos*, Bruno Sarmento*, “Colorectal Cancer Triple Co-culture Spheroid Model to Assess the Biocompatibility and Anticancer Properties of Polymeric Nanoparticles”, J. Control. Release 2020, 323, 398-411.
289. Liucheng Zhang, Yi Xiang, Hongbo Zhang, Liying Cheng, Xiyuan Mao, Ning An, Lu Zhang, Jinxiong Zhou, Lianfu Deng, Yuguang Zhang*, Xiaoming Sun*, Hélder A. Santos*, Wenguo Cui*, “Biomimetic 3D-Self-Forming Approach For Microvascular Scaffolds”, Adv. Sci. 2020, 7(9), 1903553.
288. Liucheng Zhang, Yi Xiang, Hongbo Zhang, Liying Cheng, Xiyuan Mao, Ning An, Lu Zhang, Jinxiong Zhou, Lianfu Deng, Yuguang Zhang*, Xiaoming Sun*, Hélder A. Santos*, Wenguo Cui*, “Microvascular Scaffolds: A Biomimetic 3D‐Self‐Forming Approach for Microvascular Scaffolds (Adv. Sci. 9/2020)”, Adv. Sci. 2020, 7(9), 2070050. (Issue's Back Cover Page)
287. Ulrika Jakobsson, Ermei Mäkilä, Antti Rahikkala, Surachet Imlimthan, Jarkko Lampuoti, Sanjeev Ranjan, Jouni Heino, Pasi Jalkanen, Ulli Köster, Kenichiro Mizohata, Hélder A. Santos, Jarno Salonen, Anu J. Airaksinen, Mirkka Sarparanta*, Kerttuli Helariutta*, “Preparation and In Vivo Evaluation of Red Blood Cell Membrane Coated Porous Silicon Nanoparticles Implanted with 155Tb”, Nucl. Med. Biol. 2020, 84-85, 102-110.
286. Nayab Tahir, Asadullah Madni*, Wei Li, Alexandra Correia, Muhammad Muzamil Khan, Muhammad Abdul Rahim, Hélder A. Santos*, “Microfluidic Fabrication and Characterization of Sorafenib-loaded Lipid-Polymer Hybrid Nanoparticles for Controlled Drug Delivery”, Int. J. Pharm. 2020, 581, 119275.
285. Nicola d’Avanzo, Christian Celia, Antonella Barone, Maria Carafa, Luisa Di Marzio, Hélder A. Santos*, Massimo Fresta*, “Immunogenicity of Polyethylene Glycol Based Nanomedicines: Mechanisms, Clinical Implications and Systematic Approach”, Adv. Ther. 2020, 3(3), 1900170. (Review)
284. Zehua Liu, Flavia Fontana, Andre Python, Jouni T. Hirvonen, Hélder A. Santos*, “Microfluidics for Production of Particles: Mechanism, Methodology and Applications”, Small 2020, 16(9), 1904673. (invited review for Special Issue: Microfluidics - The Fourth Decade)
283. Zehua Liu, Flavia Fontana, Andre Python, Jouni T. Hirvonen, Hélder A. Santos*, “Microfluidics: Microfluidics for Production of Particles: Mechanism, Methodology, and Applications (Small 9/2020)”, Small 2020, 16(9), 2070048. (invited review for Special Issue: Microfluidics - The Fourth Decade) (Issue's Inside Back Cover Page)
282. Mohammad-Ali Shahbazi*, Leila Faghfouri, Mónica P. A. Ferreira, Patrícia Figueiredo, Hajar Maleki, Farshid Sefatd, Jouni Hirvonen, Hélder A. Santos*, “Versatile Biomedical Applications of Bismuth-Based Nanoparticles and Composites: Therapeutic, Diagnostic, Biosensing, and Regenerative Properties”, Chem. Soc. Rev. 2020, 49(4), 1253-1321.
281. Nazanin Zanjanizadeh Ezazi, Rubina Ajdary, Alexandra Correia, Ermei M. Mäkilä, Jarno Salonen, Marianna Kemell, Jouni T. Hirvonen, Orlando J. Rojas, Heikki J Ruskoaho, Hélder A. Santos*, “Fabrication and Characterization of Drug-Loaded Conductive Poly(Glycerol Sebacate)/Nanoparticle Based Composite Patch for Myocardial Infarction Applications”, ACS Appl. Mater. Interfaces 2020, 12(6), 6899-6909.
280. Ana Cristina Q. Silva, Carla Vilela, Hélder A. Santos*, Armando J. D. Silvestre, Carmen S. R. Freire*, “Recent Trends on the Development of Systems for Cancer Diagnosis and Treatment by Microfluidic Technology”, Appl. Mater.Today 2020, 18, 100450. (Invited Review)
279. Giulia Torrieri, Flavia Fontana, Patrícia Figueiredo, Zehua Liu, Mónica P. A. Ferreira, Virpi Talman, João P. Martins, Manlio Fusciello, Karina Moslova, Tambet Teesalu, Vincenzo Cerullo, Jouni Hirvonen, Heikki Ruskoaho, Vimalkumar Balasubramanian*, Hélder A. Santos*, “Dual-Peptide Functionalized Acetalated Dextran-Based Nanoparticles for Sequential Targeting of Macrophages during Myocardial Infarction”, Nanoscale 2020, 12(4), 2350-2358.
278. Serena Bertoni, Ariella Machness, Mattia Tiboni, Raquel Bártolo, Hélder A. Santos*, “Reactive Oxygen Species Responsive Nanoplatforms as Smart Drug Delivery Systems for Gastrointestinal Tract Targeting”, Biopolym. 2020, 111(1), e23336. (invited review)
277. Serena Bertoni, Ariella Machness, Mattia Tiboni, Raquel Bártolo, Hélder A. Santos*, “Front Cover Image: Reactive Oxygen Species Responsive Nanoplatforms as Smart Drug Delivery Systems for Gastrointestinal Tract Targeting”, Biopolym. 2020, 111(1), e23291. (Issue's Front Cover Page)
276. Jiachen Li, Weiwei Zhang, Yan Gao, Haibei Tong, Zhenyu Chen, Jisen Shi*, Hélder A. Santos*, Bing Xia*, “Near-Infrared Light and Magnetic Field Dual-Responsive Porous Silicon-Based Nanocarriers to Overcome Multi-Drug Resistance of Breast Cancer Cells With Enhanced Efficiency”, J. Mater. Chem. B 2020, 8(3), 546-557.
275. Jian He, Yue Qiao, Hongbo Zhang, Jun Zhao,Wanli Li, Tingting Xie, Danni Zhong, Qiaolin Wei, Shiyuan Hua, Yinhui Yu, Ke Yao, Hélder A. Santos*, Min Zhou*, “Gold-Silver Nanoshells Promote Wound Healing from Drug-Resistant Bacteria Infection and Enable Monitoring via Surface-Enhanced Raman Scattering Imaging”, Biomaterials 2020, 234, 119763.
274. Surachet Imlimthan, Alexandra Correia, Patrícia Figueiredo, Kalle Lintinen, Vimalkumar Balasubramanian, Anu J. Airaksinen, Mauri A. Kostiainen, Hélder A. Santos, Mirkka Sarparanta*, “Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles”, J. Biomed. Mater. Res. A 2020, 108(3), 770-783.
273. Yusen Qiao, Xingzhi Liu, Xichao Zhou, Hongbo Zhang, Wen Zhang, Wei Xiao, Guoqing Pan, Wenguo Cui*, Hélder A. Santos*, Qin Shi*, “Gelatin Templated Polypeptide Co-crosslinked Hydrogel for Bone Regeneration”, Adv. Healthcare Mater. 2020, 9(1), 1901239.
272. Yusen Qiao, Xingzhi Liu, Xichao Zhou, Hongbo Zhang, Wen Zhang, Wei Xiao, Guoqing Pan, Wenguo Cui*, Hélder A. Santos*, Qin Shi*, “Osteogenic Hydrogels: Gelatin Templated Polypeptide Co‐Cross‐Linked Hydrogel for Bone Regeneration (Adv. Healthcare Mater. 1/2020)”, Adv. Healthcare Mater. 2020, 9(1), 2070001. (Issue's Front Cover Page)
271. Wei Chen, Hao Chen, Dandan Zheng, Hongbo Zhang, Lianfu Deng, Wenguo Cui, Yuhui Zhang*, Hélder A. Santos*, Hongxing Shen*, “Gene-Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus”, Adv. Sci. 2020, 7(1), 1902099.
270. Wei Chen, Hao Chen, Dandan Zheng, Hongbo Zhang, Lianfu Deng, Wenguo Cui, Yuhui Zhang*, Hélder A. Santos*, Hongxing Shen*, “Gene‐Hydrogel Microenvironments: Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus (Adv. Sci. 1/2020)”, Adv. Sci. 2020, 7(1), 2070001. (Issue's Front Cover Page)
269. Ruoyu Cheng, Lili Liu, Yi Xiang, Yong Lu, Lianfu Deng, Hongbo Zhang*, Hélder A. Santos*, Wenguo Cui*, “Advanced Liposome-Loaded Scaffolds for Therapeutic and Tissue Engineering Applications”, Biomaterials 2020, 232, 119706.
268. Vimalkumar Balasubramanian*, Andrii Domanskyi*, Juho-Matti Renko, Mirkka Sarparanta, Chang-Fang Wang*, Alexandra Correia, Ermei Mäkilä, Osku S. Alanen, Jarno Salonen, Anu J. Airaksinen, Raimo Tuominen, Jouni Hirvonen, Mikko Airavaara*, Hélder A. Santos*, “Engineered Antibody-Functionalized Porous Silicon Nanoparticles for Therapeutic Targeting of Pro-survival Pathway in Endogenous Neuroblasts After Stroke”, Biomaterials 2020, 227, 119556.
267. Cristian Vergallo, Giulia Torrieri, Riccardo Provenzani, Sini Miettinen, Karina Moslova, Markku Varjosalo, Maria Chiara Cristiano, Massimo Fresta, Christian Celia*, Hélder A. Santos*, Felisa Cilurzo*, Luisa Di Marzio, “Design, Synthesis and Characterization of a PEGylated Stanozolol for Potential Therapeutic Applications”, Int. J. Pharm. 2020, 573, 118826.
266. Saowanee Wannasarit, Shiqi Wang,* Patrícia Figueiredo, Claudia Trujillo, Francesca Eburnea, Lorena Simón-Gracia, Alexandra Correia, Yaping Ding, Tambet Teesalu, Dongfei Liu, Ruedeekorn Wiwattanapatapee, Hélder A. Santos*, Wei Li*, “A Virus-Mimicking pH-Responsive Acetalated Dextran-Based Membrane-Active Polymeric Nanoparticle for Intracellular Delivery of Antitumor Therapeutics”, Adv. Funct. Mater. 2019, 29(51), 1905352.
265. Saowanee Wannasarit, Shiqi Wang,* Patrícia Figueiredo, Claudia Trujillo, Francesca Eburnea, Lorena Simón-Gracia, Alexandra Correia, Yaping Ding, Tambet Teesalu, Dongfei Liu, Ruedeekorn Wiwattanapatapee, Hélder A. Santos*, Wei Li*, “Antitumor Therapeutics: A Virus‐Mimicking pH‐Responsive Acetalated Dextran‐Based Membrane‐Active Polymeric Nanoparticle for Intracellular Delivery of Antitumor Therapeutics (Adv. Funct. Mater. 51/2019)”, Adv. Funct. Mater. 2019, 29(51), 1905351. (Issue's Inside Back Cover Page)
264. Manlio Fusciello, Flavia Fontana, Siri Tähtinen, Cristian Capasso, Sara Feola, Beatriz Martins, Jacopo Chiaro, Karita Peltonen, Leena Ylösmäki, Erkko Ylösmäki, Firas Hamdan, Otto K. Kari, Joseph Ndika, Harri Alenius, Arto Urtti, Jouni T. Hirvonen, Hélder A. Santos*, Vincenzo Cerullo*, “Artificially Cloaked Viral Nanovaccine for Cancer Immunotherapy”, Nature Commun. 2019, 10(1), 5747.
263. Tiago Carvalho, Gabriela Guedes, Filipa L. Sousa, Carmen S. R. Freire, Hélder A. Santos*, “Latest Advances on Bacterial Cellulose-Based Materials for Wound Healing, Delivery Systems and Tissue Engineering”, Biotechnol. J. 2019, 14(12), 1900059. (Invited Review)
262. Hanif Ullah, Munair Badshah, Alexandra Correia, Fazli Wahid, Hélder A. Santos, Taous Khan*, “Functionalized Bacterial Cellulose Microparticles for Drug Delivery in Biomedical Applications”, Curr. Pharm. Des. 2019, 25(34), 3692–3701.
261. Daulat Haleem Khan, Sajid Bashir, Alexandra Correia, Muhammad Imran Khan, Patrícia Figueiredo, Hélder A. Santos, Leena Peltonen*, “Utilization of Green Formulation Technique and Efficacy Estimation on Cell Line Studies For Dual Anticancer Drug Therapy With Niosomes”, Int. J. Pharm. 2019, 572, 118764.
260. Ranjith Kumar Kankala, Hongbo Zhang, Chen-Guang Liu, Kiran Reddy Kanubaddi, Chia-Hung Lee, Shi-Bin Wang, Wenguo Cui*, Hélder A. Santos*, KaiLi Lin*, Ai-Zheng Chen*, “Metal Species-Encapsulated Mesoporous Silica Nanoparticles: Current Advancements and Latest Breakthroughs”, Adv. Funct. Mater. 2019, 29(43), 1902652. (Review)
259. Mónica P. A. Ferreira and Hélder A. Santos*, “Nanomedicines to Tackle Myocardial Infarction: Where Are We Now and Where Are We Going?”, Dosis 2019, 3, 290–298. (invited)
258. Tuying Yong, Xiaoqiong Zhang, Nana Bie, Hongbo Zhang, Xuting Zhang, Fuying Li, Abdul Hakeem, Jun Hu, Lu Gan*, Hélder A. Santos*, Xiangliang Yang*, “Tumor Exosome-Based Nanoparticles are Efficient Drug Carriers for Chemotherapy”, Nature Commun. 2019, 10(1), 3838.
257. Mohammad-Ali Shahbazi, Mónica P. A. Ferreira, Hélder A. Santos*, “Landing a Lethal Blow on Bacterial Infections: An Emerging Advance of Nanodots for Wound Healing Acceleration”, Nanomedicine (Lond.) 2019, 14(17), 2269–2272. (Invited Editorial)
256. Kalle Sakari Lintinen, Sanna Luiro, Patricia Figueiredo, Ekaterina Sakarinen, Zekra Mousavi, Jani Seitsonen, Guillaume N. Rivière, Ulriika Mattinen, Matti Niemelä, Päivi Tammela, Monika Österberg, Leena-Sisko Johansson, Johan Bobacka, Hélder A. Santos*, Mauri A. Kostiainen, “Antimicrobial Colloidal Silver-Lignin Particles via Ion- and Solvent Exchange”, ACS Sustainable Chem. Eng. 2019, 7(18), 15297–15303.
255. Tomás Bauleth-Ramos, Ting-Yu Shih, Mohammad-Ali Shahbazi, Alexander J. Najibi, Angelo S. Mao, Dongfei Liu, Pedro Granja, Hélder A. Santos*, Bruno Sarmento*, David J. Mooney*, “Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination”, Adv. Funct. Mater. 2019, 29(35), 1903686.
254. Jincheng Tang, Yong Gu, Hongbo Zhang, Liang Wu, Yun Xu, Jiannan Mao, Tianwen Xin, Tingjun Ye, Lianfu Deng, Wenguo Cui*, Hélder A. Santos*, Liang Chen*, “Outer-Inner Dual Reinforced Micro/Nano Hierarchical Scaffolds for Promoting Osteogenesis”, Nanoscale 2019, 11, 15794–15803.
253. Rubina Ajdary, Siqi Huan, Nazanin Zanjanizadeh Ezazi, Wenchao Xiang, Rafael Grande, Hélder A. Santos*, Orlando J. Rojas*, “Acetylated Nanocellulose for Single-Component Bioinks and Cell Proliferation on 3D-Printed Scaffolds”, Biomacromolecules 2019, 20(7), 2770–2778.
252. Nayab Tahir, Asadullah Madni*, Alexandra Correia, Mubashar Rehman, Vimalkumar Balasubramanian, Muhammad Muzamil Khan, Hélder A. Santos*, “Lipid-Polymer Hybrid Nanoparticles for Controlled Delivery of Hydrophilic and Lipophilic Doxorubicin for Breast Cancer Therapy”, Int. J. Nanomedicine 2019, 14, 4961–4974.
251. Hon S. Leong, Kimberly S. Butler, C. Jeffrey Brinker, May Azzawi, Steve Conlan, Christine Dufés, Andrew Owen, Steve Rannard, Chris Scott, Chunying Chen, Marina A. Dobrovolskaia, Serguei V. Kozlov, Adriele Prina-Mello, Ruth Schmid, Peter Wick, Fanny Caputo, Patrick Boisseau, Rachael M. Crist, Scott E. McNeil, Bengt Fadeel, Lang Tran, Steffen Foss Hansen, Nanna B. Hartmann, Lauge P. W. Clausen, Lars M. Skjolding, Anders Baun, Marlene Ågerstrand, Zhen Gu, Dimitrios A. Lamprou, Clare Hoskins, Leaf Huang, Wantong Song, Huiliang Cao, Xuanyong Liu, Klaus D. Jandt, Wen Jiang, Betty Y. S. Kim, Korin E. Wheeler, Andrew J. Chetwynd, Iseult Lynch, Sayed Moein Moghimi, André Nel, Tian Xia, Paul S. Weiss, Bruno Sarmento, José das Neves, Hélder A. Santos, Luis Santos, Samir Mitragotri, Steve Little, Dan Peer, Mansoor M. Amiji, Maria José Alonso, Alke Petri-Fink, Sandor Balog, Aaron Lee, Barbara Drasler, Barbara Rothen-Rutishauser, Stefan Wilhelm, Handan Acar, Roger G. Harrison, Chuanbin Mao, Priyabrata Mukherjee, Rajagopal Ramesh, Lacey R. McNally, Sara Busatto, Joy Wolfram, Paolo Bergese, Mauro Ferrari, Ronnie H. Fang, Liangfang Zhang, Jie Zheng, Chuanqi Peng, Bujie Du, Mengxiao Yu, Danielle M. Charron, Gang Zheng, Chiara Pastore, “On the Issue of Transparency and Reproducibility in Nanomedicine”, Nature Nanotechnol. 2019, 14, 629–635.
250. Flavia Fontana, Manlio Fusciello, Christianne Groeneveldt, Cristian Capasso, Jacopo Chiaro, Sara Feola, Zehua Liu, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Vincenzo Cerullo*, Hélder A. Santos*, “Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor”, ACS Nano 2019, 13(6), 6477–6490.
249. Patrícia Figueiredo*, Mika H. Sipponen, Kalle Lintinen, Alexandra Correia, Alexandros Kiriazis, Jari Yli-Kauhaluoma, Monika Österberg, Anne George, Jouni Hirvonen, Mauri A. Kostiainen, Hélder A. Santos*, “Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake”, Small 2019, 15(24), 1901427.
248. Flavia Fontana, João P. Martins, Giulia Torrieri, Hélder A. Santos* , “Nuts and Bolts: Microfluidics for the Production of Biomaterials”, Adv. Mater. Technol. 2019, 4(6), 1800611. (invited review)
247. Flavia Fontana, João P. Martins, Giulia Torrieri, Hélder A. Santos* , “Microfluidics: Nuts and Bolts: Microfluidics for the Production of Biomaterials (Adv. Mater. Technol. 6/2019)”, Adv. Mater. Technol. 2019, 4(6), 1970034. (invited review) (Issue's Inside Back Cover Page)
246. Hongbo Zhang, Wenguo Cui, Xiangmeng Qu, Huayin Wu, Liangliang Qu, Xu Zhang, Ermei Mäkilä, Jarno Salonen, Yue-Qi Zhu*, Zhou Yang, Dong Chen, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Photothermal Responsive Nanosized Hybrid Polymersome as Versatile Therapeutics Co-Delivery Nanovehicle for Effective Tumor Suppression”, Proc. Natl. Acad. Sci. U.S.A. 2019, 116(16) 7744–7749.
245. Cláudia Martins, Francisca Araújo, Maria João Gomes, Carlos Fernandes, Rute Nunes, Wei Li, Hélder A. Santos, Fernanda Borges, Bruno Sarmento*, “Using Microfluidic Platforms to Develop CNS-Targeted Polymeric Nanoparticles for HIV Therapy”, Eur. J. Pharm. Biopharm. 2019, 138, 111–124.
244. Mohammad-Ali Shahbazi*, Mahsa Sedighi, Tomás Bauleth-Ramos, Krishna Kant, Alexandra Correia, Narges Poursina, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Correction to "Targeted Reinforcement of Macrophage Reprogramming Towards M2 Polarization by IL-4 Loaded Hyaluronic Acid Particles"”, ACS Omega 2019, 4(3), 5931–5931.
243. Jukka Saarinen*, Friederike Gütter, Mervi Lindman, Mikael Agopov, Sara J. Fraser-Miller, Regina Scherließ, Eija Jokitalo, Hélder A. Santos, Leena Peltonen, Antti Isomäki, Clare J. Strachan*, “Cell-Nanoparticle Interactions at Sub(nanometer) Resolution Analysed by Electron Microscopy and Correlative Coherent Anti-Stokes Raman Scattering”, Biotechnol. J. 2019, 14(4), 1800413.
242. Ulrika Jakobsson, Ermei Mäkilä, Anu J. Airaksinen, Osku Alanen, Asenath Etilé, Ulli Köster, Sanjeev Ranjan, Jarno Salonen, Hélder A. Santos, Kerttuli Helariutta* , “Porous Silicon as a Platform for Radiation Theranostics Together With a Novel RIB Based Radiolanthanoid”, Contrast Media Mol. Imaging 2019, ID 3728563, 9.
241. Yueqi Zhu, Hongbo Zhang, Yiran Zhang, Huayin Wu, Liming Wei, Gen Zhou, Yuezhou Zhang, Lianfu Deng, Yingsheng Cheng*, Minghua Li*, Hélder A. Santos*, Wenguo Cui*, “Endovascular Metal Devices for the Treatment of Cerebrovascular Diseases”, Adv. Mater. 2019, 31(8), 1805452.
240. Yueqi Zhu, Hongbo Zhang, Yiran Zhang, Huayin Wu, Liming Wei, Gen Zhou, Yuezhou Zhang, Lianfu Deng, Yingsheng Cheng*, Minghua Li*, Hélder A. Santos*, Wenguo Cui*, “Metal‐Based Stents: Endovascular Metal Devices for the Treatment of Cerebrovascular Diseases (Adv. Mater. 8/2019)”, Adv. Mater. 2019, 31(8), 1970058. (Issue's Back Cover Page)
239. Hélder A. Santos*, “Why Academic and Industrial Scientists Should Foster Their Collaboration?”, Polymorfi 2019, 48–50. (commentary article)
238. Zehua Liu, Yunzhan Li, Wei Li*, Wenhua Lian, Marianna Kemell, Sami Hietala, Patrícia Figueiredo, Li Li, Ermei Mäkilä, Ming Ma, Jarno Salonen, Jouni T. Hirvonen, Dongfei Liu, Hongbo Zhang*, Xianming Deng*, Hélder A. Santos*, “Close-loop Dynamic Nanohybrids on Collagen-Ark with In-situ Gelling Transformation Capability for Bio-mimetically Stage Specific Diabetic Wound Healing”, Mater. Horiz. 2019, 6, 385–393.
237. Surachet Imlimthan, Sofia Otaru, Outi Keinänen, Alexandra Correia, Kalle Sakari Lintinen, Hélder A. Santos, Anu J. Airaksinen, Mauri A. Kostiainen, Mirkka Sarparanta*, “Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications”, Biomacromol. 2019, 20(2), 674–683.
236. Xiyuan Mao, Ruoyu Cheng, Hongbo Zhang, Jinhong Bae, Liying Cheng, Lu Zhang, Lianfu Deng, Wenguo Cui*, Yuguang Zhang*, Hélder A. Santos*, Xiaoming Sun*, “Correction to "Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration"”, Adv. Sci. 2019, 6(13), 1901124.
235. Xiyuan Mao, Ruoyu Cheng, Hongbo Zhang, Jinhong Bae, Liying Cheng, Lu Zhang, Lianfu Deng, Wenguo Cui*, Yuguang Zhang*, Hélder A. Santos*, Xiaoming Sun*, “Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration”, Adv. Sci. 2019, 6(3), 1801555.
234. Xiyuan Mao, Ruoyu Cheng, Hongbo Zhang, Jinhong Bae, Liying Cheng, Lu Zhang, Lianfu Deng, Wenguo Cui*, Yuguang Zhang*, Hélder A. Santos*, Xiaoming Sun*, “Self‐Healing: Self‐Healing and Injectable Hydrogel for Matching Skin Flap Regeneration (Adv. Sci. 3/2019)”, Adv. Sci. 2019, 6(3), 1970019. (Issue's Back Cover Page)
233. Yue Qiao, Yuan Ping, Hongbo Zhang, Fengyong Liu, Bo Zhou, Yinhui Yu, Tingting Xie, Wanli Li, Danni Zhong, Yuezhou Zhang, Ke Yao, Hélder A. Santos*, Min Zhou*, “Laser Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Wound Healing for Infected Chronic Nonhealing Wounds”, ACS Appl. Mater. Interfaces 2019, 11(4), 3809–3822.
232. Yufei Yan, Tao Sun, Hongbo Zhang, Xiuling Ji, Yulong Sun, Xin Zhao, Lianfu Deng, Jin Qi*,
Wenguo Cui*, Hélder A. Santos*, Hongyu Zhang*, “Euryale Ferox Seed-inspired Super-lubricated Nanoparticles for Treatment of Osteoarthritis”, Adv. Funct. Mater. 2019, 29(4), 1807559.
231. Daulat Haleem Khan, Sajid Bashir, Patrícia Figueiredo, Hélder A. Santos, Muhammad Imran Khan, Leena Peltonen*, “Process Optimization of Ecological Probe Sonication Technique for Production of Rifampicin Loaded Niosomes”, J. Drug Deliv. Sci. Technol. 2019, 50, 27–33.
230. Yaping Ding*, Wei Li, Feng Zhang, Zehua Liu, Nazanin Zanjanizadeh Ezazi, Dongfei Liu, Hélder A. Santos*, “Electrospun Fibrous Architectures for Drug Delivery, Tissue Engineering and Cancer Therapy”, Adv. Funct. Mater. 2019, 29(2), 1802852. (Invited Review)
229. Shengcai Qi, Pengfei Zhang, Ming Ma*, Minghua Yao, Jinjin Wu, Ermei Mäkilä, Jarno Salonen, Heikki Ruskoaho, Yuanzhi Xu, Hélder A. Santos*, Hongbo Zhang*, “Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells”, Small 2019, 15(1), 1804332.
228. Sarah A.P. Pereira, Marieta L.C. Passos, Alexandra Correia, Ermei Mäkilä, Jarno Salonen, André R.S.T. Araujo, Hélder A.Santos, M. Lúcia M.F.S. Saraiva*, “Automatic Methodologies to Perform Loading and Release Assays of Anticancer Drugs from Mesoporous Silicon Nanoparticles”, Talanta 2019, 196, 277–283.
227. Mohammad-Ali Shahbazi*, Mahsa Sedighi, Tomás Bauleth-Ramos, Krishna Kant, Alexandra Correia, Narges Poursina, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Targeted Reinforcement of Macrophage Reprogramming Towards M2 Polarization by IL-4 Loaded Hyaluronic Acid Particles”, ACS Omega 2018, 3(12), 18444–18455.
226. João P. Martins*, Dongfei Liu, Flavia Fontana, Mónica P. A. Ferreira, Alexandra Correia, Silvia Valentino, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Microfluidic Nanoassembly of Bioengineered Chitosan-Modified FcRn-Targeted Porous Silicon Nanoparticles @ Hypromellose Acetate Succinate for Oral Delivery of Anti-Diabetic Peptides”, ACS Appl. Mater. Interfaces 2018, 10(51), 44354–44367.
225. Serena Bertoni, Zehua Liu, Alexandra Correia, João Pedro Martins, Antti Rahikkala, Flavia Fontana, Marianna Kemell, Dongfei Liu, Beatrice Albertini, Nadia Passerini*, Wei Li*, Hélder A. Santos*, “pH And Reactive Oxygen Species-Sequential Responsive Nano-in-Micro Composite For Targeted Therapy of Inflammatory Bowel Disease”, Adv. Funct. Mater. 2018, 28(50), 1806175.
224. Serena Bertoni, Zehua Liu, Alexandra Correia, João Pedro Martins, Antti Rahikkala, Flavia Fontana, Marianna Kemell, Dongfei Liu, Beatrice Albertini, Nadia Passerini*, Wei Li*, Hélder A. Santos*, “Drug Delivery: pH and Reactive Oxygen Species‐Sequential Responsive Nano‐in‐Micro Composite for Targeted Therapy of Inflammatory Bowel Disease (Adv. Funct. Mater. 50/2018)”, Adv. Funct. Mater. 2018, 28(50), 1870353. (Issue's Front Cover Page)
223. Xingzhi Liu, Hongbo Zhang, Ruoyu Cheng, Yanzheng Gu, Yin Yin, Zhiyong Sun, Guoqing Pan, Zhongbin Deng, Huilin Yang, Lianfu Deng, Wenguo Cui*, Hélder A Santos*, Qin Shi*, “An immunological Electrospun Scaffold for Tumor Imprison Killing and Healthy Tissue Regeneration”, Mater. Horiz. 2018, 5, 1082-1091.
222. Wei Li, Yunzhan Li, Zehua Liu, Nattha Kerdsakundee, Ming Zhang, Feng Zhang, Xueyan Liu, Tomás Bauleth-Ramos, Wenhua Lian, Ermei Mäkilä, Marianna Kemell, Yaping Ding, Bruno Sarmento, Ruedeekorn Wiwattanapatapee, Jarno Salonen, Hongbo Zhang, Jouni T. Hirvonen, Dongfei Liu*, Xianming Deng*, Hélder A. Santos*, “Hierarchical Structured and Programmed Vehicles Deliver Drugs Locally to Inflamed Sites of Intestine”, Biomaterials 2018, 185, 322-332.
221. Wei Li*, Ermei Mäkilä, Jarno Salonen, Mart Saarma. Yulia Sidorova, Hélder A. Santos, "GDNF Mimetics Delivery by Porous Silicon Nanoparticles for Improved Parkinson’s Disease Management", Nanomedicine: NBM 2018,14(5), 1848. (conference paper)
220. Guanggai Xia, Hongbo Zhang, Ruoyu Cheng, Hongcheng Wang, Ziliang Song, Lianfu Deng, Xinyu Huang*, Hélder A. Santos*, Wenguo Cui*, “Localized Controlled Delivery of Gemcitabine via Microsol Electrospun Fibers to Prevent Pancreatic Cancer Recurrence”, Adv. Healthcare Mater. 2018, 7(18), 1800593.
219. Flavia Fontana, Patricia Figueiredo, Pei Zhang, Jouni T. Hirvonen, Dongfei Liu, Hélder A. Santos*, “Production of Pure Drug Nanocrystals and Nano Co-crystals by Confinement Methods”, Adv. Drug Deliv. Rev. 2018, 131, 3-21. (Invited Review)
218. Xiaoming Sun, Hongbo Zhang, Jinlin He, Ruoyu Cheng, Youwen Cao, Kunming Che, Liying Cheng, Lu Zhang, Guoqing Pan, Peihong Ni, Lianfu Deng, Yuguang Zhang*, Hélder A. Santos*, Wenguo Cui*, “Adjustable hardness of hydrogel for promoting vascularization and maintaining stemness of stem cells in skin flap regeneration”, Appl. Mater. Today 2018, 13, 54-63.
217. Mohammad-Ali Shahbazi, Tomás Bauleth-Ramos, Hélder A. Santos*, “DNA Hydrogel Assemblies: Bridging Synthesis Principles to Biomedical Applications”, Adv. Ther. 2018, 1(4), 1800042 (Invited Review)
216. Jianfeng Ji, Fei Ma, Hongbo Zhang, Fengyong Liu, Jian He, Wanlin Li, Tingting Xie, Danni Zhong, Tingting Zhang, Mei Tian*, Hong Zhang*, Hélder A. Santos*, Min Zhou*, “Light-Activatable Assembled Nanoparticles to Improve Tumor-Penetration and Eradicate Metastasis in Triple Negative Breast Cancer”, Adv. Funct. Mater. 2018, 28(33), 1801738.
215. Jianfeng Ji, Fei Ma, Hongbo Zhang, Fengyong Liu, Jian He, Wanlin Li, Tingting Xie, Danni Zhong, Tingting Zhang, Mei Tian*, Hong Zhang*, Hélder A. Santos*, Min Zhou*, “Front Cover - Cancer Therapy: Light‐Activatable Assembled Nanoparticles to Improve Tumor Penetration and Eradicate Metastasis in Triple Negative Breast Cancer (Adv. Funct. Mater. 33/2018)”, Adv. Funct. Mater. 2018, 28(33), 1870228. (Issue's Front Cover Page)
214. Antti Rahikkala, Sarah A. P. Pereira, Patrícia Figueiredo, Marieta L.C. Passos, André R. T. S. Araújo, M. Lúcia M. F. S. Saraiva*, Hélder A. Santos*, “Mesoporous Silica Nanoparticles for Targeted and Stimuli-responsive Delivery of Chemotherapeutics: A Review”, Adv. Biosys. 2018, 2(7), 1800020. (Invited Review)
213. Dongfei Liu*, Katriina Lipponen, Peng Quan, Xiaocao Wan, Hongbo Zhang, Ermei M. Mäkilä, Jarno J. Salonen, Risto Kostiainen, Jouni J. Hirvonen, Tapio Kotiaho, Hélder A. Santos*, “Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions”, ACS Biomater. Sci. Eng. 2018, 4(7), 2308–2313.
212. Dongfei Liu*, Hongbo Zhang, Flavia Fontana, Jouni T. Hirvonen, Hélder A. Santos*, “Current Developments and Applications of Microfluidic Technology Toward Clinical Translation of Nanomedicines”, Adv. Drug Deliv. Rev. 2018, 128, 54–83. (Invited Review)
211. João P. Martins*, Roberto D’Auria, Dongfei Liu, Flavia Fontana, Mónica P. A. Ferreira, Alexandra Correia, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Luca Casettari, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Engineered Multifunctional Albumin-Decorated Porous Silicon Nanoparticles for FcRn Translocation of Insulin”, Small 2018, 14(27), 1800462.
210. Hélder A. Santos*, “Materials Science in Finland (Special Issue)”, Adv. Mater. 2018, 30(24), 1802557. (Invited Editorial)
209. Hélder A. Santos*, “Cover Picture - Materials Science in Finland (Special Issue): (Adv. Mater. 24/2018)”, Adv. Mater. 2018, 30(24), 1870167. (Invited Editorial) (Issue's Front Cover Page)
208. Zehua Liu, Yunzhan Li, Wei Li, Chen Xiao, Dongfei Liu, Chao Dong, Ming Zhang, Ermei Mäkilä, Marianna Kemell, Jarno Salonen, Jouni T. Hirvonen, Hongbo Zhang*, Dawang Zhou*, Xianming Deng*, Hélder A. Santos*, “Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics”, Adv. Mater. 2018, 30(24), 1703393. Special Issue: Materials Science in Finland
207. Zehua Liu, Yunzhan Li, Wei Li, Chen Xiao, Dongfei Liu, Chao Dong, Ming Zhang, Ermei Mäkilä, Marianna Kemell, Jarno Salonen, Jouni T. Hirvonen, Hongbo Zhang*, Dawang Zhou*, Xianming Deng*, Hélder A. Santos*, “Inside Front Cover - Nanohybrids: Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics (Adv. Mater. 24/2018)”, Adv. Mater. 2018, 30(24), 1870168. (Issue's Inside Front Cover Page) Special Issue: Materials Science in Finland
206. Wei Li, Zehua Liu, Flavia Fontana, Yaping Ding, Dongfei Liu, Jouni T. Hirvonen*, Hélder A. Santos*, “Tailoring Porous Silicon for Biomedical Applications: From Drug Delivery to Cancer Immunotherapy”, Adv. Mater. 2018, 30(24), 1703740. (Invited Review) Special Issue: Materials Science in Finland
205. Flavia Fontana*, Silvia Albertini, Alexandra Correia, Marianna Kemell, Rici Lindgren, Ermei Mäkilä, Jarno Salonen, jouni Hirvonen, Franca Ferrari, Hélder A. Santos*, “Bioengineered Porous Silicon Nanoparticles @ Macrophages Cell Membrane as Composite Platforms for Rheumatoid Arthritis”, Adv. Funct. Mater. 2018, 28(22), 1801355.
204. Feng Zhang, Li Kong, Dongfei Liu, Wei Li, Ermei Mäkilä, Alexandra Correia, Rici Lindgren, Jarno Salonen, Jouni T. Hirvonen, Hongbo Zhang, Alexander Kros, Hélder A. Santos*, “Sequential Antifouling Surface for Efficient Modulation of the Nanoparticle-Cell Interactions in Protein-Rich Environment”, Adv. Ther. 2018, 1(1), 1800013.
203. Flavia Fontana, Patrícia Figueiredo, Tomás Bauleth-Ramos, Alexandra Correia, Hélder A. Santos*, “Immunostimulation and Immunosuppression: Nanotechnology on the Brink”, Small Methods 2018, 2(5), 1700347. (Invited Review)
202. Yaping Ding, Wei Li, Alexandra Correia, Yuyun Yang, Kai Zheng, Dongfei Liu, Dirk W. Schubert, Aldo R. Boccaccini, Hélder A. Santos*, Judith Anna Roether*, “Electrospun PHB/PCL/Sol-gel Derived Silica Hybrid Scaffolds with Drug Releasing Function for Bone Tissue Engineering Applications”, ACS Appl. Mater. Interfaces 2018, 10(17), 14540–14548.
201. João Pedro Martins*, Giulia Torrieri, Hélder A. Santos*, “The Importance of Microfluidics for the Preparation of Nanoparticles as Advanced Drug Delivery Systems”, Exp. Opin. Drug Deliv. 2018, 15(5), 469–479. (Invited Review)
200. Mónica P.A. Ferreira*, Virpi Talman, Giulia Torrieri, Dongfei Liu, Gonçalo Marques, Karina Moslova, Zehua Liu, João F. Pinto, Jouni Hirvonen*, Heikki Ruskoaho*, Hélder A. Santos*, “Dual-Drug Delivery Using Dextran-Functionalized Nanoparticles Targeting Cardiac Fibroblasts for Cellular Reprogramming”, Adv. Funct. Mater. 2018, 28(15), 1705134.
199. Sini M. Kinnunen, Marja Tölli, Mika J. Välimäki, Erhe Gao, Zoltan Szabo, Jaana Rysä, Mónica P.A. Ferreira, Pauli Ohukainen, Raisa Serpi, Alexandra Correia, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos, Heikki Ruskoaho*, “Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction”, Sci. Rep. 2018, 8(1), 4611.
198. Dongfei Liu, Jian Chen, Tao Jiang, Wei Li, Yao Huang, Xiyi Lu, Zehua Liu, Weixia Zhang, Zheng Zhou, Qirui Ding, Hélder A. Santos*, Guoyong Yin*, Jin Fan*, “Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity”, Adv. Mater. 2018, 30(14), 1706032.
197. Dongfei Liu, Jian Chen, Tao Jiang, Wei Li, Yao Huang, Xiyi Lu, Zehua Liu, Weixia Zhang, Zheng Zhou, Qirui Ding, Hélder A. Santos*, Guoyong Yin*, Jin Fan*, “Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018)”, Adv. Mater. 2018, 30(14), 1870095.
196. Hongbo Zhang, Yueqi Zhu, Liangliang Qu, Huayin Wu, Haixin Kong, Zhou Yang, Dong Chen, Ermei Makila, Jarno J. Salonen, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Gold Nanorods Conjugated Porous Silicon Nanoparticles Encapsulated in Calcium Alginate Nano Hydrogels Using Microemulsion Templates”, Nano Lett. 2018, 18(2), 1448–1453.
195. Zoran Cenev, Hongbo Zhang*, Veikko Sariola, Antti Rahikkala, Dongfei Liu, Hélder A. Santos*, Quan Zhou*, “Manipulating Superparamagnetic Microparticles with an Electromagnetic Needle”, Adv. Mater. Technol. 2018, 3(1), 1700177.
194. Vimalkumar Balasubramanian*, Zehua Liu, Jouni Hirvonen, Hélder A. Santos*, “Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines”, Adv. Healthcare Mater. 2018, 7(1), 1700432. (Invited Progress report)
193. Vimalkumar Balasubramanian*, Zehua Liu, Jouni Hirvonen, Hélder A. Santos*, “Inside Back Cover - Nanomedicine: Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines (Adv. Healthcare Mater. 1/2018)”, Adv. Healthcare Mater. 2018, 7(1), 1870005. (Invited Progress report) (Issue's Inside Back Cover Page)
192. Patrícia Figueiredo*, Kalle Lintinen, Jouni T. Hirvonen, Mauri A. Kostiainen, Hélder A. Santos*, “Properties and Chemical Modifications of Lignin: Towards Lignin-Based Nanomaterials for Biomedical Applications”, Prog. Mater. Sci. 2018, 93, 233–269. (Review)
191. Vimalkumar Balasubramanian, Andrea Poillucci, Alexandra Correia, Hongbo Zhang, Christian Celia,* Hélder A. Santos*, “Cell Membranes based Nanoreactor to Mimic the Bio-Compartmentalization Strategy of a Cell”, ACS Biomater. Sci. Eng. 2018, 4(4), 1471–1478.
190. Nazanin Zanjanizadeh Ezazi, Mohammad-Ali Shahbazi, Yuri V. Shatalin, Eloy Nadal, Ermei Mäkilä, Jarno Salonen, Marianna Kemell, Alexandra Correia, Jouni Hirvonen, Hélder A. Santos*, “Conductive Vancomycin-Loaded Mesoporous Silica Polypyrrole-Based Scaffolds for Bone Regeneration”, Int. J. Pharm. 2018, 536(1), 241–250.
189. Eloy G. Nadal, Barbara Herranz-Blanco, Hélder A. Santos, "Plataforma reusable de ensamblaje de capilares de vidrio para micro fluidos (Reusable glass capillary microfluidic platform)", Oficina Española de Patentes y Marcas, Spain, Patent No. ES2626263A1, 2017. (Patent)
188. Dongfei Liu, Jin Fan, Guoyong Yin, Hélder A. Santos, “Nanoparticle With Super High-Drug Loading Capacity and Manufacturing Method Thereof”, WO2017198078, 2017. (Patent)
187. Francisca Araújo, José das Neves, João Pedro Martins, Pedro L. Granja, Hélder A. Santos, Bruno Sarmento*, “Functionalized Materials for Multistage Platforms in the Oral Delivery of Biopharmaceuticals”, Prog. Mater. Sci. 2017, 89, 306–344. (Review)
186. Vimalkumar Balasubramanian*, Alexandra Correia, Hongbo Zhang, Flavia Fontana, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-like Functions”, Adv. Mater. 2017, 29(11), 1605375.
185. Vimalkumar Balasubramanian*, Alexandra Correia, Hongbo Zhang, Flavia Fontana, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Inside Front Cover - Nanoreactors: Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions (Adv. Mater. 11/2017)”, Adv. Mater. 2017. 20(11). (Issue's Inside Front Cover Page)
184. Flavia Fontana*, Mohammad-Ali Shahbazi, Dongfei Liu, Hongbo Zhang, Ermei Mäkilä, Jarno Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy”, Adv. Mater. 2017, 29(7), 1603239.
183. Flavia Fontana*, Mohammad-Ali Shahbazi, Dongfei Liu, Hongbo Zhang, Ermei Mäkilä, Jarno Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Back Cover Image - Nanovaccines: Multistaged Nanovaccines Based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy (Adv. Mater. 7/2017)”, Adv. Mater. 2017, 29(7). (Issue's Back Cover Page)
182. Dongfei Liu*, Hongbo Zhang, Salvatore Cito, Jin Fan, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Tiina M. Sikanen, David A. Weitz, Hélder A. Santos*, “Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation”, Nano Lett. 2017, 17(2), 606–614.
181. Tomás Bauleth-Ramos, Mohammad-Ali Shahbazi*, Dongfei Liu, Flavia Fontana, Alexandra Correia, Patrícia Figueiredo, Hongbo Zhang, João Pedro Martins, Jouni T. Hirvonen, Pedro Granja, Bruno Sarmento*, Hélder A. Santos*, “Nutlin-3a and Cytokine co-loaded Spermine-modified Acetalated Dextran Nanoparticles for Cancer Chemo-immunotherapy”, Adv. Funct. Mater. 2017, 27(42), 1703303.
180. Tomás Bauleth-Ramos, Mohammad-Ali Shahbazi*, Dongfei Liu, Flavia Fontana, Alexandra Correia, Patrícia Figueiredo, Hongbo Zhang, João Pedro Martins, Jouni T. Hirvonen, Pedro Granja, Bruno Sarmento*, Hélder A. Santos*, “Front Cover - Cancer Therapy: Nutlin-3a and Cytokine co-loaded Spermine-modified Acetalated Dextran Nanoparticles for Cancer Chemo-immunotherapy”, Adv. Funct. Mater. 2017, 27(42). (Issue's Front Cover Page)
179. Dongfei Liu*, Cristina Rodríguez Bernuz, Jin Fan, Wei Li, Alexandra Correia, Jouni Hirvonen, Hélder A. Santos*, “A Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals”, Adv. Funct. Mater. 2017, 27(9), 1604508.
178. Dongfei Liu*, Cristina Rodríguez Bernuz, Jin Fan, Wei Li, Alexandra Correia, Jouni Hirvonen, Hélder A. Santos*, “Back Cover Image - Drug Delivery: Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals”, Adv. Funct. Mater. 2017, 27(9). (Issue's Back Cover Page)
177. Xiaoming Sun, Qi Lang, Hongbo Zhang, Liying Cheng, Ying Zhang, Guoqing Pan, Xin Zhao, Huilin Yang, Yuguang Zhang*, Hélder A. Santos*, Wenguo Cui*, “Electrospun Photocrosslinkable Hydrogel Fibrous Scaffolds for Rapid in Vivo Vascularized Skin Flap Regeneration”, Adv. Funct. Mater. 2017, 27(2), 1604617.
176. Xiaoming Sun, Qi Lang, Hongbo Zhang, Liying Cheng, Ying Zhang, Guoqing Pan, Xin Zhao, Huilin Yang, Yuguang Zhang*, Hélder A. Santos*, Wenguo Cui*, “Front Cover Image - Cell Scaffolds: Electrospun Photocrosslinkable Hydrogel Fibrous Scaffolds for Rapid in Vivo Vascularized Skin Flap Regeneration (Adv. Funct. Mater. 2/2017)”, Adv. Funct. Mater. 2017, 27(2). (Issue's Front Cover Page)
175. Mónica P.A. Ferreira*, Sanjeev Ranjan, Sini Kinnunen, Alexandra Correia, Virpi Talman, Ermei Mäkilä, Brianda Barrios-Lopez, Marianna Kemell, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Heikki Ruskoaho*, Anu J. Airaksinen*, Hélder A. Santos*, “Drug-loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling”, Small 2017, 13(33), 1701276.
174. Mónica P.A. Ferreira*, Sanjeev Ranjan, Sini Kinnunen, Alexandra Correia, Virpi Talman, Ermei Mäkilä, Brianda Barrios-Lopez, Marianna Kemell, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Heikki Ruskoaho*, Anu J. Airaksinen*, Hélder A. Santos*, “Drug Delivery: Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling (Small 33/2017)”, Small 2017, 13(33). (Issue's Front Cover Page)
173. Agne Janoniene, Zehua Liu, Lina Baranauskiene, Ermei Mäkilä, Ming Ma, Jarno Salonen, Jouni Hirvonen, Honbgo Zhang*, Vilma Petrikaite*, Hélder A. Santos*, “A Versatile Carbonic Anhydrase IX Targeting Ligand Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging”, ACS Appl. Mater. Interfaces 2017, 9(16), 13976–13987.
172. Feng Zhang, Alexandra Correia, Ermei M. Mäkilä, Wei Li, Jarno J. Salonen, Jouni Hirvonen, Hongbo Zhang*, Hélder A. Santos*, “Receptor-Mediated Surface Charge Inversion Platform Based on Porous Silicon Nanoparticles for Efficient Cancer Cell Recognition and Combination Therapy”, ACS Appl. Mater. Interfaces 2017, 9(11), 10034–10046.
171. Patrícia Figueiredo*, Kalle Lintinen, Alexandros Kiriazis, Ville Hynninen, Zehua Liu, Tomás Bauleth Ramos, Antti Rahikkala, Alexandra Correia, Tomáš Kohout, Bruno Sarmento, Jari Yli-Kauhaluoma, Jouni Hirvonen, Olli Ikkala, Mauri A. Kostiainen, Hélder A. Santos*, “In Vitro Evaluation of Biodegradable Lignin-based Nanoparticles for Drug Delivery and Enhanced Antiproliferation Effect in Cancer Cells”, Biomaterials 2017, 121, 97–108.
170. Mohammad-Ali Shahbazi*, Patrick V. Almeida, Alexandra Correia, Barbara Herranz-Blanco, Neha Shrestha, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Intracellular Responsive Dual Delivery by Endosomolytic Polyplexes Carrying DNA Anchored Porous Silicon Nanoparticles”, J. Control. Release 2017, 249, 111–122.
169. Wei Li, Dongfei Liu, Hongbo Zhang, Alexandra Correia, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos, Hélder A. Santos*, “Microfluidic Assembly of a Nano-in-Micro Dual Drug Delivery Platform Composed of Halloysite Nanotubes and a pH-Responsive Polymer for Colon Cancer Therapy”, Acta Biomater. 2017, 48, 238–246.
168. Hongbo Zhang, Xiangmeng Qu, Hong Chen, Ruihua Ding, Dong Chen, Weixia Zhang, Xu Zhang, Hao Pei, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Fabrication of Calcium Phosphate-based Nanocomposites Containing DNA Origami, Gold nanorods and Drugs for Synergistic Anticancer Applications”, Adv. Healthcare Mater. 2017, 6(20), 1700664.
167. Nattha Kerdsakundee, Wei Li*, João Pedro Martins, Zehua Liu, Feng Zhang, Marianna Kemell, Alexandra Correia, Yaping Ding, Mikko Airavaara, Jouni Hirvonen, Ruedeekorn Wiwattanapatapee, Hélder A. Santos*, “Multifunctional Nanotube–Mucoadhesive Poly(Methyl Vinyl Ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site Specific Oral Drug Delivery”, Adv. Healthcare Mater. 2017, 6(20), 1700629.
166. Hongbo Zhang*, Dongfei Liu, Liang Wang, Zehua Liu, Runrun Wu, Agne Janoniene, Ming Ma, Guoqing Pan, Lina Baranauskiene, Linlin Zhang, Wenguo Cui, Vilma Petrikaite, Daumantas Matulis, Hongxia Zhao, Jianming Pan*, Hélder A. Santos*, “Microfluidic Encapsulation of Prickly Zinc-doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy”, Adv. Healthcare Mater. 2017, 6(11), 1601406.
165. Zehua Liu, Vimalkumar Balasubramanian, Chinmay Bhat, Mikko Vahermo, Ermei Mäkilä, Marianna Kemell, Flavia Fontana, Agne Janoniene, Vilma Petrikaite, Jarno Salonen, Jari Yli-Kauhaluoma, Jouni Hirvonen, Hongbo Zhang*, Hélder A. Santos*, “Quercetin-based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells”, Adv. Healthcare Mater. 2017, 6(3), 1601009.
164. Henni Auvinen, Hongbo Zhang, Nonappa, Alisa Kopilow, Elina H. Niemelä, Sami Nummelin, Alexandra Correia, Hélder A. Santos, Veikko Linko*, Mauri A. Kostiainen*, “Protein Coating of DNA Nanostructures for Enhanced Delivery, Stability and Immunocompatibility”, Adv. Healthcare Mater. 2017, 6(18), 1700692.
163. Henni Auvinen, Hongbo Zhang, Nonappa, Alisa Kopilow, Elina H. Niemelä, Sami Nummelin, Alexandra Correia, Hélder A. Santos, Veikko Linko*, Mauri A. Kostiainen*, “Nanobiomedicine: Protein Coating of DNA Nanostructures for Enhanced Stability and Immunocompatibility (Adv. Healthcare Mater. 18/2017)”, Adv. Healthcare Mater. 2017, 6(18). (Issue's Front Cover Page)
162. Dongfei Liu,* Hongbo Zhang, Flavia Fontana, Jouni T. Hirvonen, Hélder A. Santos*, “Microfluidic-Assisted Fabrication of Carriers for Controlled Drug Delivery”, Lab Chip 2017, 17(11), 1856–1883. (Invited Review)
161. Jiaqi Guo, Dongfei Liu, Ilari Filpponen*, Leena-Sisko Johansson, Jani-Markus Malho, Sakeena Quraishi, Falk Liebner, Hélder A. Santos, Orlando J. Rojas, “Photoluminescent Hybrids of Cellulose Nanocrystals and Carbon Quantum Dots as Cytocompatible Probes For In Vitro Bio-imaging”, Biomacromol. 2017, 18(7), 2045–2055.
160. Lauri J. Reuter, Mohammad-Ali Shahbazi, Ermei M. Mäkilä, Jarno J. Salonen, Reza Saberianfar, Rima Menassa, Hélder A. Santos, Jussi J. Joensuu, Anneli Ritala*, “Coating Nanoparticles with Plant-Produced Transferrin-Hydrophobin Fusion Protein Enhances their Uptake in Cancer Cells”, Bioconj. Chem. 2017, 28(6), 1639–1648
159. Patrícia Figueiredo*, Cláudio Ferro, Marianna Kemell, Zehua Liu, Alexandros Kiriazis, Kalle Lintinen, Helena F. Florindo, Jari Yli-Kauhaluoma, Jouni Hirvonen, Mauri A. Kostiainen, Hélder A. Santos*, “Functionalization of Carboxylated Lignin Nanoparticles for Targeted and pH-
Responsive Delivery of Anticancer Drugs”, Nanomedicine (Lond.) 2017, 12(21), 2581–2596.
158. Patrick V Almeida*, Mohammad-Ali Shahbazi, Alexandra Correia, Ermei Mäkilä, Marianna Kemell, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “A Multifunctional Nanocomplex for Enhanced Cell Uptake, Endosomal Escape and Improved Cancer Therapeutic Effect”, Nanomedicine (Lond.) 2017, 12(12), 1401–1420.
157. Flavia Fontana, Dongfei Liu, Jouni Hirvonen, Hélder A. Santos*, “Delivery of Therapeutics With Nanoparticles: What’s New in Cancer Immunotherapy?”, Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2017, 9(1), e1421. (Invited Review)
156. Flavia Fontana, Dongfei Liu, Jouni Hirvonen, Hélder A. Santos*, “Inside Cover Image: Delivery of Therapeutics With Nanoparticles: What’s New in Cancer Immunotherapy?”, Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2017, 9(1), e1459. (Issue's Inside Cover Page)
155. Nayab Tahir, Asadullah Madni*, Vimalkumar Balasubramanian, Mubashar Rehman, Alexandra Correia, Prince Muhammad Kashif, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos*, “Development and Optimization of Methotrexate-Loaded Lipid-Polymer Hybrid Nanoparticles for Controlled Drug Delivery Applications", Int. J. Pharm. 2017, 533(1), 156–168.
154. Bárbara Herranz-Blanco, Eloy Ginestar, Hongbo Zhang, Jouni Hirvonen, Hélder A. Santos*, “Microfluidics Platform for Glass Capillaries and its Application in Droplet and Nanoparticle Fabrication”, Int. J. Pharm. 2017, 516(1-2), 100–105.
153. Jukka Saarinen*, Erkan Sözeri, Sara J Fraser-Miller, Leena Peltonen, Hélder A. Santos, Antti Isomäki and Clare J. Strachan, “Insights Into Caco-2 Cell Culture Structure Using Coherent Anti-Stokes Raman Scattering (CARS) Microscopy”, Int. J. Pharm. 2017, 523(1), 270–280.
152. Tommi O. Kääriäinen*, Marianna Kemell, Marja-Leena Kääriäinen, Alexandra Correia, Hélder A. Santos, Luis M. Bimbo, Jouni Hirvonen, Pekka Hoppu, Steven M. George, David C. Cameron, Mikko Ritala, Markku Leskelä, “Surface Modification of Acetaminophen Particles by Atomic Layer Deposition”, Int. J. Pharm. 2017, 525(1), 160–174.
151. Asadullah Madni*, Muhammad Abdur Rahem, Nayab Tahir, Muhammad Sarfraz, Abdul Jabar, Mubashar Rehman, Prince Muhammad Kashif, Syed Faisal Badshah, Kifayat Ullah Khan, Hélder A. Santos*, “Non-invasive Strategies for Targeting the Posterior Segment of Eye”, Int. J. Pharm. 2017, 530(1–2), 326–345. (Review)
150. Elisa Ollikainen, Dongfei Liu, Arttu Kallio, Ermei Mäkilä, Hongbo Zhang, Jarno Salonen, Hélder A. Santos, Tiina Sikanen*, “The Impact of Porous Silicon Nanoparticles on Human Cytochrome P450 Metabolism in Human Liver Microsomes In Vitro”, Eur. J. Pharm. Sci. 2017, 104, 124–132.
149. Hanif Ullah, Munair Badshah, Ermei Mäkilä, Jarno Salonen, Mohammad-Ali Shahbazi, Hélder A. Santos*, Taous Khan*, “Fabrication, Characterization and Evaluation of Bacterial Cellulose-Based Capsule Shells for Oral Drug Delivery”, Cellulose 2017, 24(3), 1445–1454.
148. Nuno Vale*, Alexandra Correia, Sara Silva, Patrícia Figueiredo, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Jorge Pedrosa, Hélder A. Santos, Alexandra Fraga, “Preparation and Biological Evaluation of Ethionamide-Mesoporous Silicon Nanoparticles Against Mycobacterium Tuberculosis”, Bioorg. Med. Chem. Lett. 2017, 27(3), 403–405.
147. Ermei M. Mäkilä, Henri Kivelä, Neha Shrestha, Alexandra Correia, Martti Kaasalainen, Edwin Kukk, Jouni Hirvonen, Hélder A. Santos, Jarno J. Salonen*, “Influence of Surface Chemistry on Ibuprofen Adsorption and Confinement in Mesoporous Silicon Microparticles”, Langmuir 2016, 32(49), 13020–13029.
146. Feng Kong, Hongbo Zhang, Xiangmeng Qu, Xu Zhang, Dong Chen, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai*, “Drug Delivery: Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy (Adv. Mater. 46/2016)”, Adv. Mater. 2016, 28(46), 10194. (Issue's Frontispiece Page)
145. Feng Kong, Hongbo Zhang, Xiangmeng Qu, Xu Zhang, Dong Chen, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai*, “Gold Nanorods, DNA Origami and Porous Silicon Nanoparticles Functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy”, Adv. Mater. 2016, 28(46), 10195–10203.
144. Ari Ora, Erika Järvihaavisto, Hongbo Zhang, Henni Auvinen, Hélder A. Santos, Mauri A. Kostiainen*, Veikko Linko*, “Cellular Delivery of Enzyme-Loaded DNA Origami”, Chem. Commun. 2016, 52(98), 14161–14164.
143. Sanjeev Ranjan*, Flavia Fontana, Hanif Ullah, Jouni Hirvonen, Hélder A. Santos*, “Microparticles to Enhance Delivery of Drugs and Growth Factors into Wound Sites”, Ther. Deliv. 2016, 7(10), 711–732. (Review)
142. Luke Jäppinen,* Tero Jalkanen, Brigitte Sieber, Ahmed Addad, Markku Heinonen, Edwin Kukk, Ivan Radevici, Petriina Paturi, Markus Peurla, Mohammad-Ali Shahbazi, Hélder A. Santos, Rabah Boukherroub, Hellen Santos, Mika Lastusaari, Jarno Salonen, “Enhanced Photoluminescence in Acetylene-Treated ZnO Nanorods”, Nanoscale Res. Lett. 2016, 11(1), 413–423.
141. Mikhail Yuryev*, Mónica P. A. Ferreira, Vimalkumar Balasubramanian, Alexandra M. R. Correia, Ermei M. Mäkilä, Ville Jokinen, Liliia Andriichuk, Marianna Kemell, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, Claudio Rivera*, “Active Diffusion of Nanoparticles of Maternal Origin Within the Embryonic Brain”, Nanomedicine 2016, 11(19), 2471–2481.
140. Runrun Wu, Hongbo Zhang, Jianming Pan,* Hengjia Zhu, Yue Ma, Wenguo Cui, Hélder A. Santos*, Guoqing Pan*, “Cover Front Picture - Antibacterial Nanoparticles: Spatio-Design of Multidimensional Prickly Zn-Doped CuO Nanoparticle for Efficient Bacterial Killing (Adv. Mater. Interfaces 18/2016)”, Adv. Mater. Interfaces 2016, 3(18), 1600472.
139. Runrun Wu, Hongbo Zhang, Jianming Pan,* Hengjia Zhu, Yue Ma, Wenguo Cui, Hélder A. Santos*, Guoqing Pan*, “Spatio-Design of Multi-Dimensional Prickly Zn-Doped CuO Nanoparticle for Efficient Bacterial Killing”, Adv. Mater. Interfaces 2016, 3(18), 1600472.
138. Feng Kong, Hongbo Zhang, Xu Zhang, Dongfei Liu, Dong Chen, Weixia Zhang, Liyuan Zhang, Hélder A. Santos, Mingtan Hai*, “Cover Picture - Drug Co-Delivery: Biodegradable Photothermal and pH Responsive Calcium Carbonate@Phospholipid@Acetalated Dextran Hybrid Platform for Advancing Biomedical Applications (Adv. Funct. Mater. 34/2016)”, Adv. Funct. Mater. 2016, 26(34), 6138. (Issue's Inside Front Cover Page)
137. Feng Kong, Hongbo Zhang, Xu Zhang, Dongfei Liu, Dong Chen, Weixia Zhang, Liyuan Zhang, Hélder A. Santos, Mingtan Hai*, “Biodegradable Photothermal and pH Responsive Calcium Carbonate@Phospholipid@Acetalated Dextran Hybrid Platform for Advancing Biomedical Applications”, Adv. Funct. Mater. 2016, 26(34), 6158–6169.
136. Vimalkumar Balasubramanian*, Bárbara Herranz-Blanco, Patrick V. Almeida, Jouni Hirvonen, Hélder A. Santos*, “Multifaceted Polymersome Platforms: Spanning From Self-assembly To Drug Delivery and Protocells”, Prog. Polym. Sci. 2016, 60, 51–85. (Review)
135. Bárbara Herranz-Blanco*, Mohammad-Ali Shahbazi, Alexandra R. Correia, Vimalkumar Balasubramanian, Tomáš Kohout, Jouni Hirvonen, Hélder A. Santos*, “Cover Inside Front Picture - Targeted Cancer Therapy: pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin (Adv. Healthcare Mater. 15/2016)”, Adv. Healthcare Mater. 2016, 5(15), 1834. (Issue's Inside Front Cover Page)
134. Bárbara Herranz-Blanco*, Mohammad-Ali Shahbazi, Alexandra R. Correia, Vimalkumar Balasubramanian, Tomáš Kohout, Jouni Hirvonen, Hélder A. Santos*, “pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Triggered Intracellular Delivery of Doxorubicin”, Adv. Healthcare Mater. 2016, 5(15), 1904–1916.
133. Patrícia Figueiredo, Vimalkumar Balasubramanian*, Mohammad-Ali Shahbazi, Alexandra Correia, Dalin Wu, Cornelia G. Palivan, Jouni T. Hirvonen, Hélder A. Santos*, “Angiopep2-Functionalized Polymersomes for Targeted Doxorubicin Delivery to Glioblastoma Cells”, Int. J. Pharm. 2016, 511(2), 794–803.
132. Hui Guo, Dongmei Liu, Bin Gao, Xiaohui Zhang, Minli You, Hui Ren, Hongbo Zhang, Hélder A. Santos, Feng Xu*, “Antiproliferative Activity and Cellular Uptake of Evodiamine and Rutaecarpine based on 3D Tumour Models”, Molecules 2016, 21(7), 954.
131. Hanif Ullah, Hélder A. Santos*, Taous Khan*, “Applications of Bacterial Cellulose in Food, Cosmetics and Drug Delivery”, Cellulose 2016, 23(4), 2291–2314. (Review)
130. Flavia Fontana, Mónica P. A. Ferreira, Alexandra Correia, Jouni Hirvonen, Hélder A. Santos*, “Microfluidics as a Cutting-Edge Technique for Drug Delivery Applications”, J. Drug Deliv. Sci. Technol. 2016, 34, 76–87. (Review)
129. Urve Paaver, Ivo Laidmäe, Hélder A. Santos, Jouko Yliruusi, Jaan Aruväli, Karin Kogermann, Jyrki Heinämäki*, “Development of a Novel Electrospun Nanofibrous Delivery System for Poorly Water-Soluble ß-Sitosterol”, Asian J. Pharm. Sci. 2016, 11(4), 500–506.
128. Hanif Ullah, Fazli Wahid, Hélder A. Santos*, Taous Khan*, “Advances in Biomedical and Pharmaceutical Applications of Functional Bacterial Cellulose-Based Nanocomposites”, Carbohyd. Polym. 2016, 150, 330–352. (Review)
127. Dongfei Liu, Tao Jiang, Weihua Cai, Jian Chen, Hongbo Zhang, Sami Hietala, Hélder A. Santos*, Guoyong Yin*, Jin Fan*, “An In Situ Gelling Drug Delivery System For Improved Recovery After Spinal Cord Injury”, Adv. Healthcare Mater. 2016, 5(12), 1513–1521.
126. Francisca Araújo, Neha Shrestha, Maria J. Gomes, Bárbara Herranz-Blanco, Dongfei Liu, Jouni J. Hirvonen, Pedro L. Granja, Hélder A. Santos, Bruno Sarmento*, “In Vivo Dual-Delivery of Glucagon Like Peptide-1 (GLP-1) and Dipeptidyl Peptidase-4 (DPP4) Inhibitor Through Composites Prepared by Microfluidics for Diabetes Therapy”, Nanoscale 2016, 8(20), 10706–10713.
125. Neha Shrestha*, Francisca Araújo, Mohammad-Ali Shahbazi, Ermei Mäkilä, Maria João Gomes, Bárbara Herranz-Blanco, Rici Lindgren, Sari Granroth, Edwin Kukk, Jarno Salonen, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Cover Picture - Drug Delivery: Thiolation and Cell-Penetrating Peptide Surface Functionalization of Porous Silicon Nanoparticles for Oral Delivery of Insulin (Adv. Funct. Mater. 20/2016)”, Adv. Funct. Mater. 2016, 26(20), 3374. (Issue's Inside Front Cover Page)
124. Neha Shrestha*, Francisca Araújo, Mohammad-Ali Shahbazi, Ermei Mäkilä, Maria João Gomes, Bárbara Herranz-Blanco, Rici Lindgren, Sari Granroth, Edwin Kukk, Jarno Salonen, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Thiolation and Cell-Penetrating Peptide Surface Functionalization of Porous Silicon Nanoparticles for Oral Delivery of Insulin”, Adv. Funct. Mater. 2016, 26(20), 3405–3416.
123. Neha Shrestha*, Francisca Araújo, Mohammad-Ali Shahbazi, Ermei Mäkilä, Maria João Gomes, Mikko Airavaara, Esko I. Kauppinen, Janne Raula, Jarno Salonen, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, “Oral Hypoglycaemic Effect of GLP-1 and DPP4 Inhibitor Based Nanocomposites in a Diabetic Animal Model”, J. Control. Release 2016, 232, 113–119.
122. João Pedro Martins, Patrick J. Kennedy, Hélder A. Santos, Cristina Barrias, Bruno Sarmento*, “A Comprehensive Review of the Neonatal Fc Receptor and its Application in Drug Delivery”, Pharmacol. Ther. 2016, 161, 22–39. (Review)
121. Mónica P. A. Ferreira*, Sanjeev Ranjan, Alexandra M. R. Correia, Ermei M. Mäkilä, Sini M. Kinnunen, Hongbo Zhang, Mohammad-Ali Shahbazi, Patrick V. Almeida, Jarno J. Salonen, Heikki J. Ruskoaho, Anu J. Airaksinen, Jouni T. Hirvonen*, Hélder A. Santos*, “In Vitro and In Vivo Assessment of Heart-Homing Porous Silicon Nanoparticles”, Biomaterials 2016, 94, 93–104.
120. Hao Chen, Peng Jia, Hui Kang, Hongbo Zhang, Yi Liu, Peilang Yang, Yufei Yan, Guilai Zuo, Lei Guo, Min Jiang, Jin Qi, Yuanyuan Liu*, Wenguo Cui*, Hélder A. Santos*, Lianfu Deng.* , “Cover Picture - Neovascularization: Up-Regulating Hif-1a by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound (Adv. Healthcare Mater. 8/2016)”, Adv. Healthcare Mater. 2016, 5(8), 856. (Issue's Front Cover Page)
119. Hao Chen, Peng Jia, Hui Kang, Hongbo Zhang, Yi Liu, Peilang Yang, Yufei Yan, Guilai Zuo, Lei Guo, Min Jiang, Jin Qi, Yuanyuan Liu*, Wenguo Cui*, Hélder A. Santos*, Lianfu Deng.* , “Up-Regulating Hif-1a by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound”, Adv. Healthcare Mater. 2016, 5(8), 907–918.
118. Marlene Lopes, Neha Shrestha, Alexandra Correia, Mohammad-Ali Shahbazi, Bruno Sarmento, Jouni Hirvonen, Francisco Veiga, Raquel Seiça, António J. Ribeiro*, Hélder A. Santos*, “Dual Chitosan/Albumin-Coated Alginate/Dextran Sulfate Nanoparticles for Enhanced Oral Delivery of Insulin”, J. Control. Release 2016, 232, 29–41.
117. Flavia Fontana, Michela Mori, Federica Riva, Ermei Mäkilä, Dongfei Liu, Jarno Salonen, Giovanni Nicoletti, Jouni Hirvonen, Carla Caramella*, Hélder A. Santos*, “Platelet Lysate-Modified Porous Silicon Microparticles for Enhanced Cell Proliferation in Wound Healing Applications”, ACS Appl. Mater. Interfaces 2016, 8(1), 988–996.
116. Nuno Vale*, Alexandra Correia, Patrícia Figueiredo, Hélder A. Santos, “Multinuclear NMR Analysis of the Antitubercular Drug Ethionamide”, J. Mol. Struct. 2016, 1105, 286–292.
115. Elizabeth Kennedy, Leigh Canham, Hélder A. Santos, “Mesoporous Biomaterials: a Lexicon and Structured Bibliography of Reviews”, Mesoporous Biomater. 2016, 3(1), 1–14. (Editorial)
114. Francisca Araújo, Neha Shrestha, Maria J. Gomes, Dongfei Liu, Bárbara Herranz-Blanco, Jouni Hirvonen, Pedro L. Granja, Hélder A. Santos, Bruno Sarmento, “Multifunctional Tailorable Composite System as a Dual Peptide-Drug Delivery System”, Front. Bioeng. Biotechnol. 2016. (Conference Abstract)
113. Hélder A. Santos, “Preclinical Development of Porous Silicon Nanocomposites for Translational Biomedical Applications”, Front. Bioeng. Biotechnol. 2016. (Conference Abstract)
112. Hélder A. Santos*, “Microfluidics Technique to Revolutionize the Drug Delivery Field: Current Developments and Applications”, Curr. Drug Deliv. 2015, 12(6), 642–644. (Opinion paper)
111. Mohammad-Ali Shahbazi*, Ermei Mäkilä, Neha Shrestha, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Controlled Shape and Nucleation Switching of Interfacially Polymerizable Nanoassemblies by Methyl Substitution”, Chem. Mater. 2015, 27(23), 8170–8178.
110. Monica Terracciano, Mohammad-Ali Shahbazi, Alexandra Correia, Ilaria Rea, Annalisa Lamberti, Luca De Stefano*, Hélder A. Santos*, “Surface Bioengineering of Diatomite Based Nanovectors for Efficient Intracellular Uptake and Drug Delivery”, Nanoscale 2015, 7(47), 20063–20074.
109. Mónica P. A. Ferreira, Vimalkumar Balasubramanian, Jouni Hirvonen, Heikki Ruskoaho, Hélder A. Santos*, “Advanced Nanomedicines for the Treatment and Diagnosis of Myocardial Infarction and Heart Failure”, Curr. Drug Targets 2015, 16(14), 1682–1697. (Review)
108. Wujun Xu, Rinez Thapa, Dongfei Liu, Tuomo Nissinen, Sari Granroth, Ale Närvänen, Mika Suvanto, Hélder A. Santos, and Vesa-Pekka Lehto*, “Smart Porous Silicon Nanoparticles with Polymeric Coatings for Sequential Combination Therapy”, Mol. Pharmaceutics 2015, 12(11), 4038–4047.
107. M. Terracciano, A. Lamberti, H.A. Santos, N.M. Martucci, M.A. Shahbazi, A. Correira, I. Ruggiero, I. Rendina, L. De Stefano, I. Rea, “Diatomite Nanoparticles as Potential Drug Delivery Systems”, IEEE Xplore: 3rd International Conference BioPhotonics 2015, 1–3. (Conference proceeding)
106. Alexandra Correia, Mohammad-Ali Shahbazi, Ermei Mäkilä, Sérgio Almeida, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Cyclodextrin-Modified Porous Silicon Nanoparticles for Efficient Sustained Drug Delivery and Proliferation Inhibition of Breast Cancer Cells”, ACS Appl. Mater. Interfaces 2015, 7(41), 23197–23204.
105. Pedro Fonte, Francisca Araújo, Cátia Silva, Carla Pereira, Salette Reis, Hélder A. Santos, Bruno Sarmento*, “Polymeric Nanoparticles For Oral Insulin Delivery: Revisited Approaches”, Biotechnol. Adv. 2015, 33(6), 1342–1354. (Review)
104. Nicolas Darville, Jukka Saarinen, Antti Isomäki, Leonid Khriachtchev, Patrick Sterkens, Marjolein van Heerden, Pieter Annaert, Leena Peltonen, Hélder A. Santos, Clare J. Strachan, Guy Van den Mooter*, “Multimodal Non-Linear Optical Imaging for the Investigation of Drug Nano-/Microcrystal-Cell Interactions”, Eur. J. Pharm. Biopharm. 2015, 96, 338–348.
103. Francisca Araújo, Neha Shrestha, Mohammad-Ali Shahbazi, Dongfei Liu, Bárbara Herranz-Blanco, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Pedro L. Granja, Bruno Sarmento*, Hélder A. Santos*, “Microfluidic Assembly of a Multifunctional Composite System Designed for Site Specific Combined Oral Delivery of Peptide-Drugs”, ACS Nano 2015, 9(8), 8291–8302.
102. Neha Shrestha, Mohammad-Ali Shahbazi, Francisca Araújo, Ermei Mäkilä, Janne Raula, Esko I. Kauppinen, Jarno Salonen, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Multistage pH-Responsive Mucoadhesive Nanocarriers Prepared by Aerosol Flow Reactor Technology: A Controlled Dual Protein-Drug Delivery System”, Biomaterials 2015, 68, 9–20.
101. Remigijus Vasiliauskas, Dongfei Liu, Salvatore Cito, Hongbo Zhang, Mohammad-Ali Shahbazi, Tiina Sikanen, Linas Mazutis*, Hélder A. Santos*, “Simple Microfluidic Approach to Fabricate Monodisperse Hollow Microparticles For Multidrug Delivery”, ACS Appl. Mater. Interfaces 2015, 7(27), 14822–14832.
100. Jorma Roine*, Martti Kaasalainen, Markus Peurla, Alexandra Correia, Francisca Araújo, Hélder A. Santos, Matti Murtomaa, Jarno Salonen, “Controlled Dissolution of Griseofulvin Solid Dispersions From Electrosprayed Enteric Polymer Micromatrix Particles: Physicochemical Characterization and In Vitro Evaluation”, Mol. Pharmaceutics 2015, 12(7), 2254–2264.
99. Feng Kong, Xu Zhang, Hongbo Zhang, Xiangmeng Qu, Dong Chen, Mark Servos, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Mingtan Hai*, David A. Weitz*, “Inhibition of Multidrug Resistance of Cancer Cells by Co-Delivery of DNA Nanostructures and Drugs Using Porous Silicon Nanoparticles@Giant Liposomes”, Adv. Funct. Mater. 2015, 25(22), 3330–3340.
98. Mohammad-Ali Shahbazi*, Neha Shrestha, Ermei Mäkilä, Francisca Araújo, Alexandra Correia, Tomás Ramos, Bruno Sarmento, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “A Prospective Cancer Chemo-Immunotherapy Approach Mediated by Synergistic CD326 Targeted Porous Silicon Nanovectors”, Nano Res. 2015, 8(5), 1505–1521.
97. Dongfei Liu*, Salvatore Cito, Yuezhou Zhang, Chang-Fang Wang, Tiina M. Sikanen, Hélder A. Santos*, “A Versatile and Robust Microfluidic Platform towards High Throughput Synthesis of Homogeneous Nanoparticles with Tunable Properties”, Adv. Mater. 2015, 27(14), 2298–2304.
96. Dongfei Liu*, Salvatore Cito, Yuezhou Zhang, Chang-Fang Wang, Tiina M. Sikanen, Hélder A. Santos*, “Microfluidics: A Versatile and Robust Microfluidic Platform Toward High Throughput Synthesis of Homogeneous Nanoparticles with Tunable Properties”, Adv. Mater. 2015, 27(14), 2269. (Issue's Front Cover Page)
95. Bárbara Herranz-Blanco*, Dongfei Liu, Ermei Mäkilä, Mohammad-Ali Shahbazi, Eloy Ginestar, Hongbo Zhang, Vladimir Aseyev, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Drug Delivery: On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications”, Adv. Funct. Mater. 2015, 25(10), 1612. (Issue's Back Cover Page)
94. Bárbara Herranz-Blanco*, Dongfei Liu, Ermei Mäkilä, Mohammad-Ali Shahbazi, Eloy Ginestar, Hongbo Zhang, Vladimir Aseyev, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications”, Adv. Funct. Mater. 2015, 25(10), 1448–1497.
93. Chang-Fang Wang*, Ermei M. Mäkilä, Martti H. Kaasalainen, Marja V. Hagström, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Dual-Drug Delivery by Porous Silicon Nanoparticles for Improved Cellular Uptake, Sustained Release, and Combination Therapy”, Acta Biomater. 2015, 16, 206–214.
92. Leigh Canham, Hélder A. Santos, Gabriela Palestino, “Mesoporous Biomaterials – Multifunctional Materials for Future Medical Therapies and Bioanalysis”, Mesoporous Biomater. 2015, 2(1), 1–2. (Editorial)
91. Joakim Riikonen, Alexandra Correia, Miia Kovalainen, Simo Näkki, Marko Lehtonen, Jukka Leppänen, Jimi Rantanen, Wujun Xu, Francisca Araújo, Jouni Hirvonen, Kristiina Järvinen, Hélder A. Santos, Vesa-Pekka Lehto*, “Systematic In Vitro and In Vivo Study on Nanostructured Porous Silicon to Improve Oral Bioavailability of Celecoxib”, Biomaterials 2015, 52, 44–55.
90. Chang-Fang Wang*, Mirkka Sarparanta, Ermei Mäkilä, Maija Hyvönen, Pirjo Laakkonen, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Multifunctional Porous Silicon Nanoparticles for Cancer Theranostics”, Biomaterials 2015, 48, 108–118.
89. Francisca Araújo, Neha Shrestha, Pedro L. Granja, Jouni Hirvonen, Hélder A. Santos, and Bruno Sarmento*, “Safety and Toxicity Concerns of Orally Delivered Nanoparticles as Drug Carriers”, Expert Opin. Drug Metab. Toxicol. 2015, 11(3), 381–393. (Review)
88. Chang-Fang Wang*, Ermei Mäkilä, Colin Bonduelle, Jussi Rytkönen, Janne Raula, Sérgio Almeida, Ale Närvänen, Jarno Salonen, Sebastien Lecommandoux, Jouni Hirvonen, Hélder A. Santos*, “Functionalization of Alkyne-Terminated Thermally Hydrocarbonized Porous Silicon Nanoparticles With Targeting Peptides and Antifouling Polymers: Effect on the Human Plasma Protein Adsorption”, ACS Appl. Mater. Interfaces 2015, 7(3), 2006–2015.
87. Maija Nyström*, Jorma Roine, Matti Murtomaa, R. Mohan Sankaran, Hélder A. Santos, Jarno Salonen, “Solid State Transformations in Consequence of Electrospraying – A Novel Polymorphic Form of Piroxicam”, Eur. J. Pharm. Biopharm. 2015, 89, 182–189.
86. Simo Näkki, Jussi Rytkönen, Tuomo Nissinen, Cristina Florea, Joakim Riikonen, Paul Ek, Hongbo Zhang, Hélder A. Santos, Ale Närvänen, Wujun Xua*, Vesa-Pekka Lehto, “Improved Stability and Biocompatibility of Nanostructured Silicon Drug Carrier for Intravenous Administration”, Acta Biomater. 2015, 13, 207–2015.
85. Dongfei Liu*, Hongbo Zhang, Ermei Mäkilä, Jin Fan, Bárbara Herranz-Blanco, Chang-Fang Wang, Ricardo Rosa, António J. Ribeiro, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Microfluidic Assisted One-Step Fabrication of Porous Silicon@Acetalated Dextran Nanocomposites for Precisely Controlled Combination Chemotherapy”, Biomaterials 2015, 39, 249–259.
84. Mohammad-Ali Shahbazi and Hélder A. Santos*, “Revolutionary Impact of Nanovaccines In Immunotherapy”, New Horiz. Transl. Med. 2015, 2(2), 44–50. (Review)
83. Michela Mori, Patrick V. Almeida, Michela Cola, Giulia Anselmi, Ermei Mäkilä, Alexandra Correia, Jarno Salonen, Jouni Hirvonen, Carla Caramella*, Hélder A. Santos*, “In Vitro Assessment of Biopolymer-Modified Porous Silicon Microparticles For Wound Healing Applications”, Eur. J. Pharm. Biopharm. 2014, 88(3), 635–642.
82. Carla Pereira, Francisca Araújo, Pedro Granja, Hélder A. Santos, Bruno Sarmento*, “Targeting Membrane Transporters and Receptors as a mean to Optimize Orally Delivered Biotechnological based Drugs through Nanoparticle Delivery Systems”, Curr. Pharm. Biotechnol. 2014, 15(7), 650–658. (Review)
81. Francisca Araújo, Neha Shrestha, Pedro L. Granja, Jouni Hirvonen, Hélder A. Santos*, Bruno Sarmento*, “Antihyperglycemic Potential of Incretins Orally Delivered via Nano and Microsystems and Subsequent Glucoregulatory Effects”, Curr. Pharm. Biotechnol. 2014, 15(7), 609–619. (Review)
80. Andrew L. Fussell, Pei Ting Mah, Herman Offerhaus*, Sanna-Mari Niemi, Jarno Salonen, Hélder A. Santos, Clare Strachan, “Coherent Anti-Stokes Raman Scattering (CARS) Microscopy Driving the Future of Loaded Mesoporous Silica Imaging”, Acta Biomater. 2014, 10(11), 4870–4877.
79. Neha Shrestha, Francisca Araújo, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Gene Based Therapy for Type 1 Diabetes Mellitus: Viral and Non-Viral Vectors”, Diabetes Manag. 2014, 4(4), 367–380. (Review)
78. Mohammad-Ali Shahbazi*, Tahia D. Fernández, Ermei Mäkilä, Xavier Le Guével, Cristobalina Mayorga, Martti Kaasalainen, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Surface Chemistry Dependent Immunostimulative Potential of Porous Silicon Nanoplatforms”, Biomaterials 2014, 35(33), 9224–9235.
77. Francisca Araújo, Neha Shrestha, Mohammad-Ali Shahbazi, Pedro Fonte, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Pedro L. Granja, Hélder A. Santos*, Bruno Sarmento*, “The Impact of Nanoparticles on the Mucosal Translocation and Transport of GLP-1 Across the Intestinal Epithelium”, Biomaterials 2014, 35(33), 9199–9207.
76. Patrick V. Almeida, Mohammad-Ali Shahbazi, Ermei Mäkilä, Martti Kaasalainen, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Amine-Modified Hyaluronic Acid-Functionalized Porous Silicon Nanoparticles for Breast Cancer Targeting”, Nanoscale 2014, 6(11), 10377–10387.
75. Annukka M. Kallinen, Mirkka P. Sarparanta, Dongfei Liu, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, Anu J. Airaksinen*, “In Vivo Evaluation of Porous Silicon and Porous Silicon Solid Lipid Nanocomposites for Passive Targeting and Imaging”, Mol. Pharmaceutics 2014, 11(8), 2876–2886.
74. Marja A. Tölli, Mónica P. A. Ferreira, Sini M. Kinnunen, Jaana Rysä, Ermei M. Mäkilä, Zoltán Szabó, Raisa E. Serpi, Pauli J. Ohukainen, Mika J. Välimäki, Alexandra M. R. Correia, Jarno J. Salonen, Jouni T. Hirvonen, Heikki J. Ruskoaho*, Hélder A. Santos*, “In Vivo Biocompatibility of Porous Silicon Biomaterials for Drug Delivery to the Heart”, Biomaterials 2014, 35(29), 8394–8405.
73. Hongbo Zhang*, Dongfei Liu, Mohammad-Ali Shahbazi, Ermei Mäkilä, Bárbara Herranz-Blanco, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Fabrication of a Multifunctional Nano-in-Micro Drug Delivery Platform by Microfluidic Templated Encapsulation of Porous Silicon in Polymer Matrix”, Adv. Mater. 2014, 26(26), 4497–4503.
72. Jenni Pessi*, Hélder A. Santos, Inna Miroshnyk, JoukoYliruusi, David A. Weitz, Sabiruddin Mirza, “Microfluidics-Assisted Engineering of Polymeric Microcapsules with High Encapsulation Efficiency for Protein Drug Delivery”, Int. J. Pharm. 2014, 472(1-2), 82–87.
71. Mohammad-Ali Shahbazi*, Patrick V. Almeida, Ermei M. Mäkilä, Martti H. Kaasalainen, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Augmented Cellular Trafficking and Endosomal Escape of Porous Silicon Nanoparticles via Zwitterionic Bilayer Polymer Surface Engineering”, Biomaterials 2014, 35(26), 7488–7500.
70. Neha Shrestha, Mohammad-Ali Shahbazi, Francisca Araújo, Hongbo Zhang, Ermei M. Mäkilä, Jussi Kauppila, Bruno Sarmento, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Chitosan-Modified Porous Silicon Microparticles for Enhanced Permeability of Insulin Across Intestinal Cell Monolayers”, Biomaterials 2014, 35(25), 7172–7179.
69. Dongfei Liu*, Hongbo Zhang, Bárbara Herranz-Blanco, Ermei Mäkilä, Vesa-Pekka Lehto, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Microfluidic Assembly of Monodisperse Multistage pH-Responsive Polymer/Porous Silicon Composites for Precisely Controlled Multi-Drug Delivery”, Small 2014, 10(10), 2029–2038.
68. Hélder A. Santos*, Ermei Mäkilä, Anu J. Airaksinen, Luis M. Bimbo, Jouni Hirvonen*, “Porous Silicon Nanoparticles for Nanomedicine: Preparation and Biomedical Applications”, Nanomedicine 2014, 9(4), 535–554. (Review)
67. Mohammad-Ali Shahbazi*, Patrick V. Almeida, Ermei Mäkilä, Alexandra Correia, Mónica Ferreira, Martti Kaasalainen, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Poly(methyl vinyl ether-alt-maleic acid) Functionalized Porous Silicon Nanoparticles for Enhanced Stability and Cellular Internalization”, Macromol. Rapid Comm. 2014, 35(6), 624–629.
66. Ermei Mäkilä, Mónica P.A. Ferreira, Henri Kivelä, Sanna-Mari Niemi, Alexandra Correia, Mohammad-Ali Shahbazi, Jussi Kauppila, Jouni Hirvonen, Hélder A. Santos, Jarno Salonen*, “Confinement Effects on Drugs in Thermally Hydrocarbonized Porous Silicon”, Langmuir 2014, 30(8), 2196–2205.
65. Chang-Fang Wang*, Seppo Auriola, Jouni Hirvonen, Hélder A. Santos*, “Conjugation of Peptides to Antisense Interleukin-6 via Click Chemistry”, Curr. Med. Chem. 2014, 21(10), 1247–1254.
64. Bárbara Herranz-Blanco, Laura R. Arriaga, Ermei Mäkilä, Alexandra Correia, Neha Shrestha, Sabiruddin Mirza, David A. Weitz, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Microfluidic Assembly of Multistage Porous Silicon/Lipid Vesicles for Controlled Drug Release”, Lab Chip 2014, 14(6), 1083–1086.
63. Chang-Fang Wang, Ermei M. Mäkilä, Martti H. Kaasalainen, Dongfei Liu, Mirkka P. Sarparanta, Anu J. Airaksinen, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Copper-Free Azide-Alkyne Cycloaddition of Targeting Peptides to Porous Silicon Nanoparticles for Intracellular Uptake and Drug Delivery”, Biomaterials 2014, 35(4), 1257–1266.
62. Hélder A. Santos, Leena Peltonen, Tarja Limnell, Jouni Hirvonen*, “Mesoporous Materials and Nanocrystals for Enhancing the Dissolution Behavior of Poorly Water-Soluble Drugs”, Curr. Pharm. Biotechnol. 2013, 14(10), 926–938. (Review)
61. Dongfei Liu, Bárbara Herranz-Blanco, Ermei Mäkilä, Laura R. Arriaga, Sabiruddin Mirza, David A. Weitz, Niklas Sandler, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Microfluidic Templated Mesoporous Silicon-Solid Lipid Microcomposites for Sustained Drug Delivery”, ACS Appl. Mater. Interfaces 2013, 5(22), 12127–12134.
60. Hongbo Zhang, Mohammad-Ali Shahbazi, Ermei M. Mäkilä, Tiago H. da Silva, Rui L. Reis, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “Diatom Silica Microparticles for Sustained Release and Permeation Enhancement Following Oral Delivery of Prednisone and Mesalamine”, Biomaterials 2013, 34(36), 9210–9219.
59. Päivi J. Kinnari, Maija Hyvönen, Ermei M. Mäkilä, Martti H. Kaasalainen, Antti Rivinoja, Jarno J. Salonen, Jouni T. Hirvonen, Pirjo M. Laakkonen*, Hélder A. Santos*, “Tumour Homing Peptide-Functionalized Porous Silicon Nanovectors for Cancer Therapy”, Biomaterials 2013, 34(36), 9134–9141.
58. Luis M. Bimbo, Oxana V. Denisova, Ermei Mäkilä, Martti Kaasalainen, Jef K. De Brabander, Jouni Hirvonen, Jarno Salonen, Laura Kakkola, Denis Kainov, Hélder A. Santos*, “Inhibition of Influenza A Virus Infection In Vitro by Saliphenylhalamide Loaded Porous Silicon Nanoparticles”, ACS Nano 2013, 7(8), 6884–6893.
57. Mohammad-Ali Shahbazi, Mehrdad Hamidi, Ermei M. Mäkilä, Hongbo Zhang, Patrick V. Almeida, Martti Kaasalainen, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos*, “The Mechanisms of Surface Chemistry Effects of Mesoporous Silicon Nanoparticles on Immunotoxicity and Biocompatibility”, Biomaterials 2013, 34(31), 7776–7789.
56. Hélder A. Santos*, “Drug Delivery with Nanostructured Porous Silicon Nanoparticles”, SPIE Newsroom 1.7.2013.
55. Dongfei Liu*, Luis M. Bimbo, Ermei Mäkilä, Francesca Villanova, Martti Kaasalainen, Barbara Herranz, Carla M. Caramella, Vesa-Pekka Lehto, Jarno Salonen, Karl-Heinz Herzig, Jouni Hirvonen, Hélder A. Santos*, “Co-delivery of a Hydrophobic Small Molecule and a Hydrophilic Peptide by Porous Silicon Nanoparticles”, J. Control. Release 2013, 170(2), 268–278.
54. Dongfei Liu, Ermei Mäkilä, Hongbo Zhang, Barbara Herranz, Martti Kaasalainen, Päivi Kinnari, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Nanostructured Porous Silicon-Solid Lipid Nanocomposite: Towards Enhanced Cytocompatibility and Stability, Reduced Cellular Association and Prolonged Drug Release”, Adv. Funct. Mater. 2013, 23(15), 1893–1902.
53. Hélder A. Santos*, Luis M. Bimbo, Barbara Herranz, Mohammad-Ali Shahbazi, Jouni Hirvonen, Jarno Salonen, “Nanostructured Porous Silicon in Preclinical Imaging: Moving From Bench to Bed Side”, J. Mater. Res. 2013, 28(2), 152–164. (Review)
52. Mohammad-Ali Shahbazi and Hélder A. Santos*, “Improving Oral Absorption via Drug-Loaded Nanocarriers: Absorption Mechanisms, Intestinal Models and Rational Fabrication”, Curr. Drug Metab. 2013, 14(1), 28–56. (Review)
51. Michela Mori, Anu J. Airaksinen, Jouni Hirvonen, Hélder A. Santos*, Carla Caramella*, “Evaluation of the Physicochemical and Biopharmaceutical Properties of Fluoro-Indomethacin”, Curr. Drug Metab. 2013, 14(1), 80–89.
50. Nuno Vale*, Paula Gomes, Hélder A. Santos*, “Metabolism of the Antituberculosis Drug Ethionamide”, Curr. Drug Metab. 2013, 14(1), 151–158. (Review)
49. Hélder A. Santos*, “Non-Animal Models Used in Drug Discovery: Drug Absorption and Metabolism”, Curr. Drug Metab. 2013, 14(1), 2–3. (Editorial)
48. H. Zhang, M.-A. Shahbazi, E. Mäkilä, T.H. Silva, R.L. Reis, J.J. Salonen, J. Hirvonen, H.A. Santos, “Sustained Release of Prednisone and Mesalamine from Diatom Exoskeletons: Bioinspiration for the Development of Safe Oral Drug Delivery Devices to Tackle Gastrointestinal diseases”, J. Tissue Eng. Regen. Med. 2013, 7(S1), S33.
47. A. Kallinen, D.F. Liu, E. Mäkilä, M. Sarparanta, J. Salonen, J. Hirvonen, H.A. Santos, A.J. Airaksinen, “F-18-Radiolabeled Solid Lipid Nanocomposite Porous Silicon Nanoparticles for Studying the Tumour Accumulation of the Particles”, J. Labelled Comp. Rad. 2013, 56(S1), S252.
46. M. Sarparanta, L.M. Bimbo, J.J. Rytkönen, E. Mäkilä, J. Salonen, H.A. Santos, T. Laaksonen, J. Hirvonen, V.-P. Lehto, P. Laaksonen, M.B. Linder, A.J. Airaksinen, “Effects of Hydrophobin-Biofunctionalization on the In Vivo Behavior of F-18-Radiolabeled Porous Silicon Drug Delivery Systems”, J. Labelled Comp. Rad. 2013, 56(S1), S251.
45. Hélder A. Santos*, “Porous-Based Biomaterials for Tissue Engineering and Drug Delivery Applications”, Biomatter. 2012, 2(4), 237–238. (Editorial)
44. Mohammad-Ali Shahbazi, Barbara Herranz, Hélder A. Santos*, “Nanostructured Porous Si-Based Nanoparticles For Targeted Drug Delivery”, Biomatter 2012 2(4), 296–312. (Review)
43. Francisca Araújo, Pedro Fonte, Hélder A. Santos, Bruno Sarmento*, “Oral Delivery of GLP-1 and Analogs: Alternatives for Diabetes Control?”, J. Diabetes Sci. Tech. 2012, 6(6), 1486–1497. (Review)
42. Ermei Mäkilä, Luis M. Bimbo, Martti Kaasalainen, Barbara Herranz, Anu J. Airaksinen, Markku Heinonen, Edwin Kukk, Jouni Hirvonen, Hélder A. Santos, Jarno Salonen*, “Amine-Modification of Thermally Carbonized Porous Silicon with Silane Coupling Chemistry”, Langmuir 2012, 28(39), 14045–14054.
41. Luis M. Bimbo,* Leena Peltonen, Jouni Hirvonen, Hélder A. Santos*, “Toxicological Profile of Therapeutic Nanodelivery Systems”, Curr. Drug Metab. 2012, 13(8), 1068–1086. (Review)
40. Hélder A. Santos and Jouni Hirvonen*, “Nanostructured Porous Silicon Materials: Potential Candidates For Improving Drug Delivery”, Nanomedicine 2012, 7(9), 1281–1285. (Editorial)
39. Anna Shevchenko*, Luis M. Bimbo, Inna Miroshnyk, Jorma Haarala, Kristýna Jelínková, Kaisa Syrjänen, Bert van Veen, Juha Kiesvaara, Hélder A. Santos, Jouko Yliruusi, “A New Cocrystal and Salts of Itraconazole: Comparison of Solid-State Properties, Stability and Dissolution Behavior”, Int. J. Pharm. 2012, 436(1–2), 403–409.
38. Nuno Vale*, Ermei Mäkilä, Jarno Salonen, Paula Gomes, Jouni Hirvonen, Hélder A. Santos*, “New times, New Trends for Ethionamide: In Vitro Evaluation of Drug-Loaded Thermally Carbonized Porous Silicon Microparticles”, Eur. J. Pharm. Biopharm. 2012, 81(2), 314–323.
37. Luis M. Bimbo*, Mirkka Sarparanta, Ermei Mäkilä, Timo Laaksonen, Päivi Laaksonen, Jarno Salonen, Markus B. Linder, Jouni Hirvonen, Anu J. Airaksinen, Hélder A. Santos*, “Cellular Interactions of Surface Modified Nanoporous Silicon Particles”, Nanoscale 2012, 4(10), 3184–3192.
36. Mirkka Sarparanta,* Luis M. Bimbo, Jussi Rytkönen, Ermei Mäkilä, Timo J. Laaksonen, Päivi Laaksonen, Markus Nyman, Jarno Salonen, Markus B. Linder, Jouni Hirvonen, Hélder A. Santos, Anu J. Airaksinen, “Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution”, Mol. Pharmaceutics 2012, 9(3), 654–663.
35. Mirkka P. Sarparanta*, Luis M. Bimbo, Ermei M. Mäkilä, Jarno J. Salonen, Päivi H. Laaksonen, A.M. Kerttuli Helariutta, Markus B. Linder, Jouni T. Hirvonen, Timo J. Laaksonen, Hélder A. Santos, Anu J. Airaksinen*, “The Mucoadhesive and Gastroretentive Properties of Hydrophobin-Coated Porous Silicon Nanoparticle Oral Drug Delivery Systems”, Biomaterials 2012, 33(11), 3353–3362.
34. Maria Tahvanainen*, Tanja Rotko, Ermei Mäkilä, Hélder A. Santos, Diogo Neves, Timo Laaksonen, Aki Kallonen, Keijo Hämäläinen, Marko Peura, Ritva Serimaa, Jarno Salonen, Jouni Hirvonen, Leena Peltonen, “Tablet Preformulations of Indomethacin-Loaded Mesoporous Silicon Microparticles”, Int. J. Pharm. 2012, 422(1-2), 125–131.
33. Hélder A. Santos*, “Porous Silicon- Revolutionising Drug Targeting and Delivery”, NANO - the magazine for small science 2012, (24), 19–22. (Featured article - invited)
32. Mirkka Sarparanta*, Ermei Mäkilä, Teemu Heikkilä, Jarno Juhani Salonen, Edwin Kukk, Vesa-Pekka Lehto, Hélder A. Santos, Jouni Hirvonen, Anu Johanna Airaksinen*, “18F-Labeled Modified Porous Silicon Particles for Investigation of Drug Delivery Carrier Distribution In Vivo with Positron Emission Tomography”, Mol. Pharmaceutics 2011, 8(5), 1799–1806.
31. Luis M. Bimbo,* Ermei Mäkilä, Janne Raula, Timo Laaksonen, Päivi Laaksonen, Katharina Strommer, Esko I. Kauppinen, Jarno Salonen, Markus B. Linder, Jouni Hirvonen, Hélder A. Santos*, “Functional Hydrophobin-Coating of Thermally Hydrocarbonized Porous Silicon Microparticles”, Biomaterials 2011, 32(34), 9089–9099.
30. Tarja Limnell,* Teemu Heikkilä,* Hélder A. Santos, Sanna Sistonen, Sanna Hellstén, Timo Laaksonen, Leena Peltonen, Narendra Kumar, Dmitry Yu. Murzin, Marjatta Louhi-Kultanen, Jarno Salonen, Jouni Hirvonen, Vesa-Pekka Lehto, “Physicochemical Stability of High Indomethacin Payload Ordered Mesoporous Silica MCM-41 and SBA-15 Microparticles”, Int. J. Pharm. 2011, 416(1), 242–251.
29. Hélder A. Santos*, “Innovative Technologies for Drug Delivery Applications: From Biopolymers and Nanocapsules to Inorganic Materials”, Curr. Drug Discov. Tech. 2011, 8(3), 155–156. (Editorial)
28. Hélder A. Santos*, Luis M. Bimbo, Vesa-Pekka Lehto, Anu J. Airaksinen, Jarno Salonen, Jouni Hirvonen, “Multifunctional Porous Silicon for Therapeutic Drug Delivery and Imaging”, Curr. Drug Discov. Tech. 2011, 8(3), 228–249. (Review)
27. Päivi Kinnari, Ermei Mäkilä, Teemu Heikkilä, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Comparison of Mesoporous Silicon and Non-Ordered Mesoporous Silica Materials as Drug Carriers for Itraconazole”, Int. J. Pharm. 2011, 414(1–2), 148–156.
26. Tarja Limnell*, Hélder A. Santos, Ermei Mäkilä, Teemu Heikkilä, Jarno Salonen, Dmitry Yu. Murzin, Narendra Kumar, Timo Laaksonen, Leena Peltonen, Jouni Hirvonen, “Drug Delivery Formulations of Ordered and non-Ordered Mesoporous Silica: Comparison of Three Drug Loading Methods”, J. Pharm. Sci. 2011, 100(8), 3294–3306.
25. Hélder A. Santos, Jarno Salonen, Luis M. Bimbo, Vesa-Pekka Lehto, Leena Peltonen, Jouni Hirvonen*, “Mesoporous Materials as Controlled Drug Delivery Formulations”, J. Drug Deliv. Sci. Tech. 2011 , 21(2), 139–155. (Review)
24. Luis M. Bimbo*, Ermei Mäkilä, Timo Laaksonen, Vesa-Pekka Lehto, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos*, “Drug Permeation Across Intestinal Epithelial Cells Using Porous Silicon Nanoparticles”, Biomaterials 2011, 32(10), 2625–2633.
23. Mirkka Sarparanta*, Luis M. Bimbo, Ermei Mäkilä, Jarno Salonen, Hélder A. Santos, Timo Laaksonen, Jouni Hirvonen, Vesa-Pekka Lehto, Päivi Laaksonen, Markkus B. Linder, Anu .J. Airaksinen, “Fluorine-18 Radiolabeling as a Tool to Evaluate Novel Porous Silicon Based Nano- and Microcarriers for Drug Delivery”, J. Labelled Comp. Rad. 2011, 54(S1), S538.
22. T. Limnell, E. MäKilä, T. Heikkilä, J. Salonen, D.Y. Murzin, N. Kumar, T. Laaksonen, L. Peltonen, J. Hirvonen, H. A. Santos*, "Preparation and Characterization of Drug Formulations of Ordered and Nonordered Mesoporous Silica Microparticles", Eur. J. Pharm. Sci. 2011, 44(S1), S125-S126.
21. L.M. Bimbo*, M. Sarparanta, E. Mäkilä, T. Laaksonen, L. Peltonen, V.-P. Lehto, A.J. Airaksinen, J. Salonen, J. Hirvonen, H. A. Santos, "Mesoporous Silicon Particles as Biocompatible Drug Delivery Agents", Eur. J. Pharm. Sci. 2011, 44(S1), S129-S130.
20. P. Kinnari*, E. Mäkilä, T. Heikkilä, J. Salonen, J. Hirvonen, H. A. Santos, "Stability Studies of Itraconazole-Loaded Mesoporous Silicon and Non-Ordered Mesoporous Silica Microparticles", Eur. J. Pharm. Sci. 2011, 44(S1), S131-S132.
19. Luis M. Bimbo, Mirkka Sarparanta, Hélder A. Santos*, Anu J. Airaksinen, Ermei Mälkiä, Timo Laaksonen, Leena Peltonen, Vesa-Pekka Lehto, Jouni Hirvonen, Jarno Salonen*, “Biocompatibility of Thermally Hydrocarbonized Porous Silicon Nanoparticles and their Biodistribution in Rats”, ACS Nano 2010, 4(6), 3023–3032.
(This paper is also part of the 'The International Council on Nanotechnology (ICON) – The Virtual Journal of Nanotechnology Environment, Health and Safety')
18. Vera V. Pinto*, Maria José Ferreira, Ricardo Silva, Hélder A. Santos, F. Silva, Carlos M. Pereira*, “Long Time Effect on the Stability of Silver Nanoparticles in Aqueous Medium: The Effect of Synthesis and Storage Conditions”, Colloids Surf. A 2010, 364(1–3), 19–25.
17. Hélder A. Santos*, Joakim Riikonen, Jarno Salonen, Teemu Heikkilä, Ermei Mälkiä, Timo Laaksonen, Leena Peltonen, Vesa-Pekka Lehto, Jouni Hirvonen, “In Vitro Cytotoxicity of Porous Silicon Microparticles: Effect of the Particle Concentration, Surface Chemistry and Size” , Acta Biomater. 2010, 6(7), 2721–2731.
(This paper is also part of the 'The International Council on Nanotechnology (ICON) – The Virtual Journal of Nanotechnology Environment, Health and Safety')
16. Teemu Heikkila*, Hélder A. Santos, Narendra Kumar, Dmitry Yu. Murzi, Jarno Salonen, Timo Laaksonen, Leena Peltonen, Jouni Hirvonen, Vesa-Pekka Lehto, “Cytotoxicity Study of Ordered Mesoporous Silica MCM-41 and SBA-15 Microparticles on Caco-2 Cells” , Eur. J. Pharm. Biopharm. 2010, 74(3), 483–494.
(This paper is also part of the 'The International Council on Nanotechnology (ICON) – The Virtual Journal of Nanotechnology Environment, Health and Safety')
15. Hélder A. Santos*, Luis M. Bimbo, Jarno Salonen, Vesa-Pekka Lehto, Jouni Hirvonen, "Tailoring In Vitro Cell Responses of Porous Silicon Micro- and Nanoparticles", Control. Release Soc. Newslett., 2010, 27(1), 10–11. (Scientifically speaking - invited)
14. Hélder A. Santos*, Vladimir García-Morales, Carlos M. Pereira, “Electrochemical Properties of Phospholipid Monolayers at Liquid-Liquid Interfaces ”, ChemPhysChem 2010, 11(1), 28–41. (Review)
13. Jouni Hirvonen*, Timo Laaksonen, Leena Peltonen, Hélder Santos, Vesa-Pekka Lehto, Teemu Heikkilä, Joakim Riikonen, Ermei Mälkiä, Jarno Salonen, “Feasibility of Silicon-Based Mesoporous Materials for Oral Drug Delivery Applications”, Dosis 2008, 24(2), 129–149 (Special Issue of Dosis for the Helsinki Drug Research 2008). (Review)
12. H. A. Santos*, J. Riikonen, T. Heikkilä, J. Salonen, L. Peltonen, E. Mäkilä, T. Laaksonen, N. Kumar, D. Murzin, V.-P. Lehto, J. Hirvonen, "Biocompatibility of Mesoporous Silicon Microparticles", Eur. J. Pharm. Sci. 2008, 34(1), S36–S37.
11. T. Laaksonen*, T. Limnell, H. Santos, T. Heikkilä, J. Riikonen, J. Salonen, L. Peltonen, V.-P. Lehto, J. Hirvonen, "Drug Dissolution Studies on Mesoporous Silicon Particles – a Theoretical Approach", Eur. J. Pharm. Sci. 2008, 34(1), S35.
10. Timo Laaksonen*, Hélder Santos, Henna Vihola, Jarno Salonen, Joakim Riikonen, Teemu Heikkilä, Leena Peltonen, Narendra Kumar, Dmitry Yu. Murzin, Vesa-Pekka Lehto, Jouni Hirvonen, “Failure of MTT as a Toxicity Testing Agent for Mesoporous Silicon Microparticles", Chem. Res. Toxicol. 2007, 20(12), 1913–1918.
9. Hélder A. Santos*, José A. Manzanares, Lasse Mortumäki, Kyösti Kontturi*, “Thermodynamic Analysis of Binding Between Drugs and Glycosaminoglycans by Isothermal Titration Calorimetry and Fluorescence Spectroscopy”, Eur. J. Pharm. Sci. 2007, 32(2), 105–114.
8. Hélder A. Santos*, Elisabete S. Ferreira, Elisa J. Pereira, Carlos M. Pereira*, Kyösti Kontturi, Fernando Silva, “Adsorption–Penetration Studies of Glucose Oxidase Into Phospholipid Monolayers at the 1,2–Dichloroethane/Water Interface", ChemPhysChem 2007, 8(10), 1540–1547.
7. Hélder A. Santos*, Sanna Carlsson, Lasse Mortumäki, Kyösti Kontturi*, “Effect of Gramicidin on Phospholipid-Modified Monolayers and on Ion transfer at a Liquid–Liquid Interface”, ChemPhysChem 2007, 8(6), 913–920 (Issue’s Cover Picture, p 769).
6. M.C. Martins, C.M. Pereira*, H.A. Santos, R. Dabirian, F. Silva, V. García-Morales, J.A. Manzanares, “Analysis of Adsorption of Phospholipids at the 1,2-Dichloroethane/Water Interface by Electrochemical Impedance Spectroscopy: a Study of the Effect of the Saturated Alkyl Chain”, J. Electroanal. Chem. 2007, 599(2), 367–375 (Special Issue In Honour of Prof. David Schiffrin).
5. Hélder A. Santos*, Vladimir García-Morales, Lasse Murtomäki, José A. Manzanares, Kyösti Kontturi*, “Preparation of Nanostructures Composed of Dextran-Sulfate Ruthenium Nanoparticles and Their Interaction With Phospholipid Monolayers at a Liquid–Liquid Interface”, J. Electroanal. Chem. 2007, 599(2), 194–202 (Special Issue In Honour of Prof. David Schiffrin).
4. Hélder A. Santos*, Mariana Chirea, Vladimir García-Morales, Fernando Silva, José A. Manzanares, Kyösti Kontturi*, “Electrochemical Study of Interfacial Composite Nanostructures: Polyelectrolyte/Gold Nanoparticle Multilayers Assembled on Phospholipid/Dextran Sulfate Monolayers at a Liquid–Liquid Interface”, J. Phys. Chem. B 2005, 109(43), 20105–20114.
3. Hélder A. Santos, Vladimir García-Morales, Robbert-Jan Roozeman, José A. Manzanares, Kyösti Kontturi*, “Interfacial Interaction Between Dextran Sulfate and Lipid Monolayers: an Electrochemical Study”, Langmuir 2005, 21(12), 5475–5484.
2. H.A. Santos, C.M. Pereira*, F. Silva, “Ion Transfer Through DPPC Films", Port. Electrochim. Acta 2005, 23(2), 263–274.
1. P.A. Fernandes, A.T.P. Carvalho, A.T. Marques, A.L.F. Pereira, A.P.S. Madeira, A.S.P. Ribeiro, A.F.R. Carvalho, E.T.A. Ricardo, F.J.V. Pinto, H.A. Santos, H.D.G. Mangericão, H.M. Martins, H.D.B. Pinto, H.R.R. Santos, I.S. Moreira, M.J.V. Azeredo, R.P.S. Abreu, R.M.S. Oliveira, S.F.M. Sousa, R.J.A.M. Silva, Z.S. Mourão & M.J. Ramos*, “New Designs for MRI Contrast Agents", J. Comput.-Aided Mol. Design 2003, 17(7), 463–473.
[39] Soraia Pinto, Neha Shrestha, Francisca Araújo, Jouni Hirvonen, Hélder A. Santos H.A.* Bruno Sarmento, Chapter 3.1: Cell-based In Vitro Models for Buccal Permeability Studies. In: Concepts and Models for Drug Permeability Studies (Second Edition): Cell and Tissue Based in Vitro Culture Models, Sarmento B., Pereira C. L., das Neves J. (Eds.), Elsevier Ltd. 2024, 45–65.
[38] João P. Martins, Hélder A. Santos*, Chapter 13: Microfluidics as a Tool for the Synthesis of Advanced Drug Delivery Systems. In: Nano- and Microfabrication Techniques in Drug Delivery, Lamprou D. (Ed.), Springer Nature Switzerland AG, 2023, 321–364.
[37] Flavia Fontana, Zehua Liu, jouni Hirvonen, Hélder A. Santos*, Chapter 18: Porous Silicon Materials for Cancer and Immunotherapy. In: Porous Silicon For Biomedical Applications, Santos H. A. (Ed.), 2ndEdition, Elsevier Ltd., 2021, 571–630.
[36] Hélder A. Santos (Editor), Porous Silicon For Biomedical Applications, 2ndEdition, Elsevier Ltd., 2021, 1–646.
35. Patrícia Figueiredo, Hélder A. Santos*, Chapter 6: Requirements and Properties of Biomaterials for Biomedical Applications. In: Lignin-Based Materials for Biomedical Applications, Santos H. A. and Figueiredo P. (Eds.), Elsevier Ltd. 2021, 195–225.
34. Surachet Imlimthan, Patrícia Figueiredo, Hélder A. Santos, Mirkka Sarparanta*, Chapter 1: Introduction to lignocellulosic materials. In: Lignin-Based Materials for Biomedical Applications, Santos H. A. and Figueiredo P. (Eds.), Elsevier Ltd. 2021, 1–33.
33. Hélder A. Santos*, Patrícia Figueiredo, Lignin-Based Materials for Biomedical, Santos H. A. and Figueiredo P. (Eds.), 1st Edition, Elsevier Ltd. 2021, 1–450.
32. Cristian Vergallo, Muhammad Nadeem Hafeez, Dalila Iannotta, Hélder A. Santos, Nicola D’Avanzo, Luciana Dini, Felisa Cilurzo, Massimo Fresta, Luisa Di Marzio, Celia Christian*, Chapter 1: Conventional Nanosized Drug Delivery Systems for Cancer Applications. In: Bio-Nanomedicine for Cancer Therapy, Santos H. A. and Fontana F. (Eds.), Springer Nature Switzerland AG 2021, 3–27.
31. Flavia Fontana, Raquél Bartolo, Hélder A. Santos*, Chapter 7: Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds. In: Bio-Nanomedicine for Cancer Therapy, Santos H. A. and Fontana F. (Eds.), Springer Nature Switzerland AG 2021, 135–162.
30. Flavia Fontana, Hélder A. Santos* (Editors), Bio-Nanomedicine for Cancer Therapy, 1st Edition, Springer Nature Switzerland AG 2021, 1–368.
29. Flavia Fontana, Nazanin Ezazi, Nayab Tahir, Helder A. Santos,* "Chapter 6: Cell-Nanoparticle Interactions: Toxicity and Safety Issues". In: Characterization of Pharmaceutical Nano and Microsystems, Peltonen L. (Ed.), Wiley-VCH Verlag GmbH. 2020, 207–242.
28. Mónica P. A. Ferreira, João Pedro Martins, Jouni Hirvonen, Hélder A. Santos*, "Chapter 9: Spray-drying for the formulation of oral drug delivery systems". In: Nanotechnology For Oral Drug Delivery: From Concept to Applications, Martins J. P., Santos H. A. (Eds.), Elsevier B.V. 2020, 253–284.
27. João Pedro Martins, Hélder A. Santos*, "Chapter 1: Oral drug delivery: Overview". In: Nanotechnology For Oral Drug Delivery: From Concept to Applications, Martins J. P., Santos H. A. (Eds.), Elsevier B.V. 2020, 3–5.
26. João Pedro Martins, Hélder A. Santos*, "Nanotechnology For Oral Drug Delivery: From Concept to Applications", 1st Edition, Elsevier Ltd. 2020, 1–517.
25. Patrícia Figueiredo, Flavia Fontana, Hélder A. Santos*, "Chapter 13: Nanomedicine Therapies". In: Handbook of In Vivo Chemistry in Mice: From Lab to Living System, Tanaka K., Vong K. (Eds.), Elsevier B.V. 2020, 373–400.
24. Flavia Fontana, Patrícia Figueiredo, Hélder A. Santos*, "Chapter 10: Advanced Nanovaccines for Immunotherapy Applications: from Concept to Animal Test". In: Theranostic Bionanomaterials, Cui W., Zhao X. (Eds.), Elsevier B.V. 2019, 231–260.
23. Feng Zhang, Hélder A. Santos,* "Chapter 8: Photosensitive Materials for Constructing On-Demanded Drug Release Systems". In: Photoactive Inorganic Nanoparticles, Prieto J. P. and Bejar M. G. (Eds.), Elsevier B.V. 2019, 193–210.
22. Helder Santos*, Dongfei Liu, and Hongbo Zhang (Eds.), “Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery", 1st Edition, Elsevier Ltd. 2018, 1–495.
21. Yuezhou Zhang, Dongfei Liu, Hongbo Zhang, Hélder A. Santos*, "Chapter 7: Microfluidic Mixing and Devices for Preparing Nanoparticulate Drug Delivery Systems". In: Microfluidics for pharmaceutical applications: from nano/micro systems fabrication to controlled drug delivery, Santos H. A., Liu D., and Zhang H. (Eds.), Elsevier B.V. 2018, 155–177.
20. Patrícia Figueiredo, Tomás Bauleth-Ramos, Jouni Hirvonen, Bruno Sarmento, Hélder A. Santos*, "Chapter 1: The Emerging Role of Multifunctional Theranostic Materials in Cancer Nanomedicine". In: Handbook of Nanomaterials for Cancer Theranostics, Conde J. (Ed.), Elsevier B.V. 2018, 1–31.
19. Antti Rahikkala, Jessica Rosenholm, Hélder A. Santos*, “Chapter 16: Biofunctionalized Mesoporous Silica Nanomaterials for Targeted Drug Delivery”. In: Biomedical Applications of Functionalized Nanomaterials, das Neves J. and Sarmento B. (Eds.), Elsevier B.V. 2018, 489–520.
18. Monica Terracciano*, Ilaria Rea, Luca De Stefano, Hélder A. Santos*, “Chapter 9: Diatoms: A Natural Source of Nanostructured Silica for Drug Delivery”. In: Diatom Nanotechnology: Progress and Emerging Applications, D. Losic (Ed.), Royal Society of Chemistry 2018, 201–218.
17. João Pedro Martins, Mónica P. A. Ferreira, Nazanin Zanjanizadeh Ezazi, Jouni T. Hirvonen, Hélder A. Santos*, “Chapter 4.1: Smart 3D Printing and Nanomaterials for Tissue Regeneration”. In: Nanotechnologies for Preventive and Regenerative Medicine, V. Uskokovic (Ed.), Elsevier B.V. 2018, 299–349.
16. Paolo Decuzzi, Alessandro Coclite, Aeju Lee, Anna Lisa Palange, Daniele Di Mascolo, Ciro Chiappini, Hélder A. Santos, Maria Laura Coluccio, Gerardo Perozziello, Patrizio Candeloro, Enzo Di Fabrizio, Francesco Gentile*, “Chapter 21: Nanoparticles for Biomedical Applications”. In: Springer Handbook of Nanotechnology, B. Bhushan (Ed.), 4th Edition, Springer Science + Business Media 2017, 635–683.
15. Hélder A. Santos*, “Chemotherapy with Porous Silicon”. In: Handbook of Porous Silicon, L. Canham (Ed.), Springer Science + Business Media 2016, 1–15.
14. Monica Terracciano, Luca De Stefano, Hélder A. Santos, Nicola M. Martucci, Angela Tino, Immacolata Ruggiero, Ivo Rendina,Nunzia Migliaccio, Claudia Tortiglione, Annalisa Lamberti, Ilaria Rea*, “Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications”. In: Algae - Organisms for Imminent Biotechnology, InTech 2016, 211–235.
13. Francisca Araújo, Carla Pereira, Hélder A. Santos, Pedro L. Granja, Bruno Sarmento*, “Functionalized Nanoparticles for Targeting the Gastrointestinal Apical Membrane Receptors”. In e-book: Advances and Challenges in Oral Delivery of Macromolecules, Future Science Group 2016, 140–164.
12. Neha Shrestha, Francisca Araújo, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos*, “Chapter 3: Cell-based In Vitro Models for Buccal Permeability Studies”. In: Concepts and Models for Drug Permeability Studies, B. Sarmento (Ed.), Elsevier Ltd. 2016, 31–40.
11. Mohammad-Ali Shahbazi, Kobra Rostamizadeh, Mehrdad Hamidi, Hélder A. Santos*, “Copolymers: Drug Delivery”. In: Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, M. Mishra (Ed.), Taylor & Francis 2015, 2192–2202.
10. Mónica Ferreira, Patrick Almeida, Mohammad-Ali Shahbazi, Alexandra Correia, Hélder A. Santos*, “Chapter 5: Current Trends and Developments for Nanotechnology in Cancer”. In: Biomedical Chemistry: Current Trends and Developments, N. Vale (Ed.), De Gruyter Open 2015, 290–342.
9. Chang-Fang Wang and Hélder A. Santos*, “Copper-Free Click Chemistry Modification of Nanovectors For Integrin Targeted Cancer Therapy”. In: Integrins in Pharmacology - Methods in Pharmacology and Toxicology, Y. J. Kang and D. C. Casey (Eds.), Springer Science + Business Media 2015, 1–15.
8. Hélder A. Santos, Luis M. Bimbo, Leena Peltonen, Jouni Hirvonen*, “Chapter 18: Inorganic Nanoparticles in Targeted Drug Delivery and Imaging”. In: Targeted Drug Delivery – Concepts and Design, J. Sanyog and P. Devarajan (Eds.), Springer Science + Business Media 2015, 571–613.
7. Hongbo Zhang, Mohammad-Ali Shahbazi, Patrick Almeida, Hélder A. Santos*, “Chapter 3: Mucus as a Barrier for Biopharmaceuticals and Drug Delivery Systems”. In: Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies, B. Sarmento and J. das Neves (Eds.), Springer Science + Business Media 2014, 59–97.
6. Hélder A. Santos* (Ed.), “Porous Silicon For Biomedical Applications ", Elsevier Ltd. 2014, 1–526.
5. Dongfei Liu, Mohammad-Ali Shahbazi, Luis M. Bimbo, Jouni Hirvonen, Hélder A. Santos*, “Chapter 7: Biocompatibility of Porous Silicon Materials”. In: Porous Silicon For Biomedical Applications, H.A. Santos (Ed.), Elsevier Ltd. 2014, 129–181.
4. Hélder A. Santos*, Ermei Mäkilä, Luis M. Bimbo, Patrick Almeida, Jouni Hirvonen, “Chapter 10: Porous Silicon Nanoparticles”. In: Fundamentals of Pharmaceutical Nanoscience, I.J. Uchegbu, A.G. Schätzlein, W.P. Cheng, and A. Lalatsa (Eds.), Springer Science + Business Media 2013, 235–275.
3. Vesa-Pekka Lehto*, Jarno Salonen, Hélder A. Santos, Joakim Riikonen, “Chapter 15: Nanostructured Silicon Based Materials as a Drug Delivery System for Water Insoluble Drugs”. In: Drug Delivery Strategies for Poorly Water-Soluble Drugs, D. Douroumis and A. Fahr (Eds.), Wiley-Blackwell 2013, 477–508.
2. Hélder A. Santos*, Jarno Salonen and Luis M. Bimbo, “Porous Silicon for Drug Delivery”. In: Encyclopedia of Metalloproteins, R.H. Kretsinger, V.N. Uversky and E.A. Permyakov (Eds.), Springer Science + Business Media 2013, New York, 1773–1781.
1. Hélder A. Santos, Luis M. Bimbo, José das Neves, Bruno Sarmento*, “Chapter 9: Nanoparticulate Targeted Drug Delivery Using Peptides and Proteins”. In: Nanomedicine: Technologies and Applications , J.T. Webster (Ed.), Elsevier Ltd. 2012, No. 49, 236–301.
Hélder A. Santos, “Applications of Nanomedicines: Cancer Diseases - Fabrication of Nanomedicines for Precisely Controlled Combination Therapy (53 mins)”, in Webster, T.J. (ed.), Nanomedicine, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London, 2015. (Online talk)
Hélder A. Santos*, “Nano-Medicine" (in English; Copyright © Technology Academy Finland 2014), in Better Life - Millennium Technology Prize 10th Jubilee publication, TAF 2014 , Finland. (Featured article)
Hélder A. Santos*, “Porous Silicon- Revolutionising Drug Targeting and Delivery”, NANO - the magazine for small science 2012, (24), 19–22. (Featured article - invited)
Newspaper news: "Nanohituset vievät lääkeaineet entistä paremmin kohteeseensa", Aamulehti, p. B22 (Section: Science Today), 16.12.2009 (in Finnish).
News: "Nanoteknologiasta apua myös laihdutukseen", Academy of Finland, 25.11.2009 (in Finnish).
Prize press release news (Prof. Jouni Hirvonen, his group and collaborators): "CRS/Eurand Grand Prize Award on Innovations in Oral Drug Delivery Technologies in 2007", 34th Annual Meeting of the Controlled Release Society, Long Beach-California, USA, 21.10.2007.