Structural Biology of Macromolecules and Interactions
Laboratory of Structural Biology
Our research in the Laboratory of Structural Biology aims at understanding the structure and function of biological macromolecules and their complexes, such as those involved in cellular cargo transport, protein folding, cell-cell contacts and viral infection. We strive to decipher basic principles in their assembly and function by structural biology methods, notably cryogenic electron microscopy (cryo-EM). We are also actively developing computational data analysis and sample tagging and capture methods for cryo-EM. Detailed mechanistic understanding of proteins involved in disease is informing rational design of therapies. We are based in the Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE.
The Laboratory of Structural Biology, headed by Professor Juha Huiskonen, was established in September 2017. The current and former...
We apply a broad range of molecular biology, structural biology, and bio-imaging methods in our research. Cryogenic transmission electron...
We have published 70 articles in leading international journals including Nature and Cell. Here you can find out about our latest...
Juha Huiskonen appointed as Director of Institute of Biotechnology at the University of Helsinki
Huiskonen will assume the position in September and alongside his director duties continues structural biology research.
Unveiling how the genome has condensed itself inside the virus
Scientists at the University of Helsinki working in collaboration with the University of Oxford have deciphered for the first time how a virus...
Resources for exploring structures of macromolecules and learning about methods we use to study them.