We provide joint services and facilities for tissue processing, slide digitization as well as automated and expert-based tissue evaluation and consultation. Our platform consists of five core-facility units, two research groups and and a laser capture microdissection instrument.
Services
Histotechnology and laser microdissection
The Histology Core Facility in Viikki
- Self-service: paraffin embedding, sectioning (paraffin, cryo-, plastic and vibratome), histological stainings
- Histotechnological assistance, training and service in the above techniques
Tissue Preparation and Histochemistry Unit (TPHU) in Meilahti
- Histotechnological services: paraffin embedding, paraffin and cryosectioning, various histological stainings
- Immunohistochemical staining and in-situ hybridization services and facilities; antibodies against intermediate filaments
Finnish Centre for Laboratory Animal Pathology and
LCM instrument in Viikki
- Histotechnological services: paraffin embedding, paraffin and cryosectioning, various histological and immunohistochemical stainings (user supplied antibodies can also be used)
- Zeiss PALM MicroBeam laser microdissection instrument for dissection and collection of samples from histological sections and cell cultures
Slide scanning
Institute of Biotechnology digital slide scanner in Viikki
High throughput whole-slide scanning; bright field
- 3D HISTECH Scanner 20x (NA 0.8), 40x (NA 0.95) air objectives
FIMM Digital microscopy and molecular pathology unit in Meilahti
High throughput whole-slide scanning; bright field and fluorescence
- 3D HISTECH Pannoramic 250 Flash II, 20x (NA 0.8), 40x (NA 0.95) air objectives
- Zeiss Azio Imager Z2, 20x, 40x and 63x (NA 1.4) oil objectives
- Zeiss Azio Scan Z.1 with 20x (NA 0.8) and 40x (NA 0.95) air objectives. Macroslide (52 mm x 76 mm) scanning possibility
GBU Digital Slide Scanner in Meilahti
High throughput whole-slide scanning; bright field and fluorescence
- 3D HISTECH Pannoramic 250 Flash II, 20x (NA 0.8), 40x (NA 0.95) air objectives
Expert support/collaboration
Finnish Centre for Laboratory Animal Pathology
- Veterinary pathology expertise and consultation for research projects involving experimental animals
- Laboratory animal pathology services
Molecular, Cellular and Transgene Neurodegeneration Team
- CNS image investigation, neuronal stereology consulting and neuronal morphology analysis
- Extensive and unique set of in vivo and in vitro tools to study neurodegeneration
Clinical Informatics and Image-based Diagnostics
- Microscopy image based diagnostics
- High-throughput computer assisted methods for automated analysis of digitized cancer tissue and microbiological samples. Computerized quantification and segmentation of digitized tumour samples.