We provide joint services and facilities for tissue processing, slide digitization as well as automated and expert-based tissue evaluation and consultation. Our platform consists of five core-facility units, two research groups and and a laser capture microdissection instrument.
Services
The Histology Core Facility in Viikki
- Self-service: paraffin embedding, sectioning (paraffin, cryo-, plastic and vibratome), histological stainings
- Histotechnological assistance, training and service in the above techniques
Tissue Preparation and Histochemistry Unit (TPHU) in Meilahti
- Histotechnological services: paraffin embedding, paraffin and cryosectioning, various histological stainings
- Immunohistochemical staining and in-situ hybridization services and facilities; antibodies against intermediate filaments
Finnish Centre for Laboratory Animal Pathology and
LCM instrument in Viikki
- Histotechnological services: paraffin embedding, paraffin and cryosectioning, various histological and immunohistochemical stainings (user supplied antibodies can also be used)
- Zeiss PALM MicroBeam laser microdissection instrument for dissection and collection of samples from histological sections and cell cultures
Institute of Biotechnology digital slide scanner in Viikki
High throughput whole-slide scanning; bright field
- 3D HISTECH Scanner 20x (NA 0.8), 40x (NA 0.95) air objectives
FIMM Digital microscopy and molecular pathology unit in Meilahti
High throughput whole-slide scanning; bright field and fluorescence
- 3D HISTECH Pannoramic 250 Flash II, 20x (NA 0.8), 40x (NA 0.95) air objectives
- Zeiss Azio Imager Z2, 20x, 40x and 63x (NA 1.4) oil objectives
- Zeiss Azio Scan Z.1 with 20x (NA 0.8) and 40x (NA 0.95) air objectives. Macroslide (52 mm x 76 mm) scanning possibility
GBU Digital Slide Scanner in Meilahti
High throughput whole-slide scanning; bright field and fluorescence
- 3D HISTECH Pannoramic 250 Flash II, 20x (NA 0.8), 40x (NA 0.95) air objectives
Finnish Centre for Laboratory Animal Pathology
- Veterinary pathology expertise and consultation for research projects involving experimental animals
- Laboratory animal pathology services
Molecular, Cellular and Transgene Neurodegeneration Team
- CNS image investigation, neuronal stereology consulting and neuronal morphology analysis
- Extensive and unique set of in vivo and in vitro tools to study neurodegeneration
Clinical Informatics and Image-based Diagnostics
- Microscopy image based diagnostics
- High-throughput computer assisted methods for automated analysis of digitized cancer tissue and microbiological samples. Computerized quantification and segmentation of digitized tumour samples.