Artikkelit

2D Assignment and quantitative analysis of cellulose and oxidized celluloses using solution-state NMR spectroscopy

Koso, T., Rico del Cerro, D., Heikkinen, S., Nypelö, T., Buffiere, J., Perea-Buceta, J.E., Potthast, A., Rosenau, T., Heikkinen, H., Maaheimo, H., Isogai, A., Kilpeläinen, I., King, A.W.T

Cellulose, 2020, 27, 7929-7953.

 

In situ analysis of liposome hard and soft protein corona structure and composition in a single label-free workflow

Kari, O., Ndika, J., Parkkila, P., Louna, A., Lajunen,T., Puustinen, A., Viitala, T., Alenius, H. and Urtti, A.

Nanoscale, 2020, 12, 1728-1741.

 

Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure

Rostila, A., Anttila, S.L., Lalowski, M.M., Vuopala, K.,Toljamo, T., Lindström, I., Baumann, M.H. and Puustinen A.

Eur. J. Cancer Prev., 2020; 29, 238-247

 

Studying the metabolism of toxic chemical warfare agent-related phenylarsenic chemicals in vitro in cod liver

Niemikoski, H., Koske, D., Kammann, U., Lang, T., Vanninen, P.

J. Hazard. Mater. 2020, 2020 Jun 5;391:122221. DOI:/10.1016/j.jhazmat.2020.122221. Epub 2020 Feb 3.

 

Derivatization and rapid GC-MS screening of chlorides relevant to the Chemical Weapons Convention in organic liquid samples

Kuitunen, M-L., Cecilia Altamirano, J., Siegenthaler, P., Taure, T. H., Hakkinen, V. A. & Vanninen, P. S.

Analytical Methods 2020, 12, 19, 2527-2535.

 

Identification of Degradation Products of Sea-Dumped Chemical Warfare Agent-Related Phenylarsenic Chemicals in Marine Sediment

Niemikoski, H., Söderströn, M., Kiljunen, H., Östin, A., Vanninen, P

Anal Chem, 2020, 92, 7, 4891-4899. DOI:/10.1021/acs.analchem.9b04681

 

Quantum mechanical reference spectrum simulation for precursors and degradation products of chemicals relevant to the Chemical Weapons Convention, Magnetic Resonance in Chemistry

Koskela, H., Cavalcante S. F. de A., Ahmed, S., Vanninen, P.

First published: 31 August 2020, DOI:/10.1002/mrc.5090.

 

Identification of Pu and U isotopic composition and its applications in environmental and CBRN research

Salminen-Paatero, S., Vanninen, P. & Paatero, J.

Defence technology, 2020. DOI:/10.1016/j.dt.2020.05.007.

 

Biological effects of dumped chemical weapons in the Baltic Sea: A multi-biomarker study using caged mussels at the Bornholm main dumping site

astumäki, A., Turja, R., Brenner, M., Vanninen, P.,   Niemikoski N., Butrimavičienė L., Stankevičiūtė M., Lehtonen K.

Marine Environmental Research, 161, 2020, 105036. DOI:/10.1016/j.marenvres.2020.105036.

 

Exposure status of sea-dumped chemical warfare agents in the Baltic Sea

Vanninen, P., Östin, A., Bełdowski, J., Pedersen, E.A., Söderström, M., Szubska, M., Grabowski, M., Siedlewicz, M.,  Czub, M.,  Popiel, S., Nawała, J., Dziedzic, D., Jakacki, J., Pączek, B.

Marine Environmental Research, 161, 2020, DOI:/10.1016/j.marenvres.2020.105112.

 

A fast, miniaturized, real-time unit for sampling, modulation and separation in detection of hazardous chemicals

Pallis, George; Psarras, George; Vamvakari, Julia; Kuula, Matti; Kiljunen, Harri; Lignell, Hanna; Vanninen, Paula

Analytical Chemistry, 2020, DOI:/10.1021/acs.analchem.0c02898

 

Metabolism of a Bioorthogonal PET Tracer Candidate [19F/18F]SiFA-Tetrazine in Mouse Liver Microsomes: Biotransformation Pathways and Defluorination Investigated by UHPLC-HRMS

Hanna Niemikoski, Mirkka Sarparanta, and Anu J. Airaksinen

Orcid http://orcid.org/0000-0002-6578-4227

 

Detection of Chemical Warfare Agent Related Phenylarsenic Compounds and Multi-Biomarker Responses in Cod (Gadus Morhua) from Munition Dumpsites.

Hanna Niemikoski, Katharina Straumer, Aino Ahvo, Raisa Turja, Matthias Brenner, Tomi Rautanen, Thomas Lang, Kari K. Lehtonen, and Paula Vanninen

Marine Environmental Research, 2020, DOI:/10.1016/j.marenvres.2020.105160

Reactive oxygen species-regulating proteins peroxiredoxin 2 and thioredoxin, and glyceraldehyde-3-phosphate dehydrogenase are differentially abundant in induced sputum from smokers with lung cancer or asbestos exposure

Rostila, A., Anttila, S.L., Lalowski, M.M., Vuopala, K.,Toljamo, T., Lindström, I., Baumann, M.H. and Puustinen, A.

European J. Cancer Prev., 2019, DOI:/10.1097/CEJ.0000000000000537

 

A pilot clinical study of the neuromuscular blocker rocuronium to reduce the duration of ventilation after organophosphorus insecticide poisoning

Dhanarisi, J., Shihana, F., Harju, K., Mohamed, F., Verma, V., Shahmy, S., Vanninen, P., Kostiainen, O., Gawarammana, I., Eddleston, M

Clin. Toxicol., 2019, Jul 31:1-8. DOI:/10.1080/15563650.2019.1643467

 

Toxic effects of chemical warfare agent mixtures on the mussel Mytilus trossulus in the Baltic Sea: A laboratory exposure study

Hoeher, N., Turja, R., Brenner, M., Nyholm, J. R., Östin, A., Leffler, P., Butrimaviciene, L., Barsiene, J., Halme, M., Karjalainen, M., Niemikoski, H., Vanninen, P., Broeg, K., Lehtonen, K. K., Berglind, R.

Mar Environ Res. 2019, 145, 112-122

 

Advice on assistance and protection from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 2. On preventing and treating health effects from acute, prolonged, and repeated nerve agent exposure, and the identification of medical countermeasures able to reduce or eliminate the longer term health effects of nerve agents

Timperley, C. M.; Abdollahi, M.; Al-Amri, A. S.; Baulig, A.; Benachour, D.; Borrett, V.; Carino, F. A.; Geist, M.; Gonzalez, D.; Kane, W.; Kovarik, Z.; Martinez-Alvarez, R.; Fusaro Mourao, N. M.; Neffe, S.; Raza, S. K.; Rubaylo, V.; Suarez, A. G.; Takeuchi, K.; Tang, C.; Trifiro, F.; van Straten, F. M.; Vanninen, P. S.; Vucinic, S.; Zaitsev, V.; Zafar-Uz-Zaman, M.; Zina, M. S.; Holen, S.; Forman, J. E.; Alwan, W. S.; Suri, V

Toxicology 2019, 13-23.

 

Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 1. On medical care and treatment of injuries from blister and nerve agents

Timperley, C. M.; Forman, J. E.; Abdollahi, M.; Al-Amri, A. S.; Baulig, A.; Benachour, D.; Borrett, V.; Carino, F. A.; Geist, M.; Gonzalez, D.; Kane, W.; Kovarik, Z.; Martinez-Alvarez, R.; Fusaro Mourao, N. M.; Neffe, S.; Raza, S. K.; Rubaylo, V.; Suarez, A. G.; Takeuchi, K.; Tang, C.; Trifiro, F.; van Straten, F. M.; Vanninen, P. S.; Vucinic, S.; Zaitsev, V.; Zafar-Uz-Zaman, M.; Zina, M. S.; Holen, S.

Toxicology 2019.

 

Molecularly Imprinted Polymer Materials as Selective Recognition Sorbents for Explosives : A Review

Zarejousheghani , M , Lorenz , W , Vanninen , P , Alizadeh , T , Cämmerer , M & Borsdorf , H

Polymers , vol. 11 , no. 5 , 888 . DOI:/10.3390/polym11050888

 

Chemical profiles of birch and alder bark by ambient mass spectrometry

Räsänen, R-M., Hieta, J-P., Immanen, J., Nieminen, K., Haavikko, R., Yli-Kauhaluoma, J. & Kauppila, T.

Nov 2019, In : Analytical and Bioanalytical Chemistry. 411, 28, p. 7573-7583 11 p.

 

Osteoporosis and skeletal dysplasia caused by pathogenic variants in SGMS2

Pekkinen, M., Terhal, P. A., Botto, L. D., Henning, P., Mäkitie, R. E., Roschger, P., Jain, A., Kol, M., Kjellberg, M. A., Paschalis, E. P., van Gassen, K., Murray, M., Bayrak-Toydemir, P., Magnusson, M. K., Jans, J., Kausar, M., Carey, J. C., Somerharju, P., Lerner, U. H., Olkkonen, V. M. & 3 others

4 Apr 2019, In : JCI INSIGHT. 4, 7, 20 p., 126180.

 

Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark

Alonso Serra, J. A., Safronov, O., Lim, K-J., Fraser-Miller, S., Blokhina, O. B., Campilho, A., Chong, S-L., Fagerstedt, K. V., Haavikko, R. H., Helariutta, Y., Immanen, J. J. M., Kangasjärvi, J. S., Kauppila, T. J., Lehtonen, M., Ragni, L., Rajaraman, S., Räsänen, R-M., Safdari, P., Tenkanen, T. M., Yli-Kauhaluoma, J. T. & 4 others

Jun 2019, In : New Phytologist. 222, 4, p. 1816-1831 16 p.

pH-Dependent Piecewise Linear Correlation of 1H,31P Chemical Shifts: Application in NMR Identification of Nerve Agent Metabolites in Urine Samples

Koskela, H., Andjelkovic, B., Pettersson, A., Rapinoja, M.; Kuitunen, M.; Vanninen, P

Anal. Chem. 2018, 14, 8495-8500

 

Liquid-state NMR analysis of nanocelluloses

King, A. W. T., Mäkelä, V.. Kedzior, S. A., Laaksonen, T., Partl, G. J., Heikkinen, S., Koskela, H., Heikkinen, H. A., Holding, A. J., Cranston, E. D., Kilpelainen, I

Biomacromolecules 2018, 7, 2708-2720

 

Advice from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons on riot control agents in connection to the Chemical Weapons Convention

Timperley, C. M., Forman, J. E., Aas, P., Abdollahi, M., Benachour, D., Al-Amri, A. S., Baulig, A., Becker-Arnold, R., Borrett, V., Carino, F. A., Curty, C., Gonzalez, D., Geist, M., Kane, W., Kovarik, Z., Martinez-Alvarez, R., Mikulak, R., Fusaro Mourao, N. M., Neffe, S., De Souza Nogueira, E., Ramasami, P., Raza, S. K., Rubaylo, V., Saeed, A. E. M., Takeuchi, K., Tang, C., Trifiro, F., Mauritz van Straten, F., Suarez, A. G., Waqar, F., Vanninen, P. S., Zafar-Uz-Zaman, M., Vucinic, S., Zaitsev, V., Zina, M. S., Holen, S., Izzati, F. N.

RSC Adv. 2018, 73, 41731-41739.

 

Advice on chemical weapons sample stability and storage provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons to increase investigative capabilities worldwide.

Timperley, C. M., Forman, J. E., Abdollahi, M., Al-Amri, A. S., Alonso, I. P., Baulig, A., Borrett, V., Carino, F. A., Curty, C., Berrutti, D. G., Kovarik, Z., Martinez-Alvarez, R., Mikulak, R., Mourao, N. M. F., Ponnadurai, R., Neffe, S., Raza, S. K., Rubaylo, V., Takeuchi, K., Tang, C., Trifiro, F., van Straten, F. M., Vanninen, P. S., Zaitsev, V., Waqar, F., Zina, M. S., Blum, M., Gregg, H., Fischer, E., Sun, S., Yang, P.

Talanta 2018, 808-832.

 

Advice from the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons on isotopically labelled chemicals and stereoisomers in relation to the Chemical Weapons Convention.

Timperley, C. M., Forman, J. E., Abdollahi, M., Al-Amri, A. S., Alonso, I. P., Baulig, A., Borrett, V., Carino, F. A., Curty, C., Gonzalez, D., Kovarik, Z., Martinez-Alvarez, R., Mikulak, R., Fusaro Mourao, N. M., Ramasami, P., Neffe, S., Raza, S. K., Rubaylo, V., Takeuchi, K., Tang, C., Trifiro, F., van Straten, F. M., Vanninen, P. S., Zaitsev, V., Waqar, F., Zina, M. S., Holen, S., Weinstein, H. A.

Pure Appl. Chem. 2018, 10, 1647-1670.

NMR chemical shift and J coupling parameterization and quantum mechanical reference spectrum simulation for selected nerve agent degradation products in aqueous conditions

Koskela H., Anđelković B.

Magn. Reson. Chem., 55, 917–927 (2017).

 

Toxin variability estimations of 68 Alexandrium ostenfeldii (dinophyceae) strains from the Netherlands reveal a novel abundant gymnodimine

Martens H., Tillmann U., Harju K., Dell’Aversano C., Tartaglione L., Krock B.

Microorganisms, 5 (2017) 29.

 

Detection of Chemical Warfare Agent-Related Phenylarsenic Aompounds in Marine Biota Samples by LC-HESI/MSMS

Niemikoski H., Söderström M., Vanninen P.

Anal. Chem., 89 (2017) 11129–11134

Specific Noncompetitive Immunoassay for HT-2 Mycotoxin Detection

Arola, H.O., Tullila, A., Kiljunen, H., Campbell, K., Siitari, H., Nevanen, T.K.

Anal Chem., 88 (2016) 2446–2452.

 

Chemical munitions search & assessment – An evaluation of the dumped munitions problem in the Baltic Sea

Bełdowski J., Klusek Z., Szubska M., Turja R., Bulczak A.I., Rak D., Brenner M., Lang T., Kotwicki L., Grzelak K., Jakacki J., Fricke N., Östin A., Olsson U., Fabisiak J., Garnaga G., Rattfelt Nyholm J., Majewski P., Broeg K., Söderström M., Vanninen P., Popiel S., Nawała J., Lehtonen K., Berglind R., Schmidt B.

Deep-Sea Research, Part II, 128 (2016) 85–95.

 

Arsenic concentration in Baltic Sea sediments close to chemical munition dumpsites

Bełdowski J., Szubska M., Emelyanov E., Garnaga G., Drzewińska A., Bełdowska M., Vanninen P., Östin, A., Fabisik J.

Deep-Sea Research, Part II, 128 (2016) 114–122.

 

Biological Toxins of Potential Bioterrorism Risk: Current Status of Detection and Identification Technology

Dorner, B.G.; Zeleny, R.; Harju, K.; Hennekinne, J.-A.; Vanninen, P.; Schimmel, H.; Rummel, A.

Trends in Analytical Chemistry 85 (2016) 89–102.

 

Comparison of in vitro metabolism and cytotoxicity of capsaicin and dihydrocapsaicin

Halme M., Pesonen M., Salo H., Söderström M., Pasanen M., Vähäkangas K., Vanninen P.

J. Chromatogr. B, 1009 (2016) 17–24.

 

Identification of gymnodimine D and presence of gymnodimine variants in the dinoflagellate Alexandrium ostenfeldii from the Baltic Sea

Harju, K., Koskela, H., Kremp, A., Suikkanen, S., de la Iglesia, P., Miles, C.O., Krock, B., Vanninen, P.

Toxicon, 112 (2016)  68–76.

 

ME-CAGEBIRDr,X-CPMG-HSQMBC. A Phase Sensitive, Multiplicity Edited Long Range HSQC with Absorptive Line Shapes

Koskela, H., Kilpeläinen, I., Heikkinen, S.

J. Magn Reson. (2016), 272, 114-122.

 

Quantity of the dinoflagellate sxtA4 gene and cell density correlates with paralytic shellfish toxin production in Alexandrium ostenfeldii blooms

Savela, H., Harju, K., Spoof, L., Lindehoff, E., Meriluoto J., Vehniäinen, M., Kremp, A.

Harmful Algae, 52 (2016) 1–10.

 

Application of comprehensive NMR-based analysis strategy in annotation, isolation and structure elucidation of low molecular weight metabolites of Ricinus communis seeds

Vučković I., Rapinoja M.-L., Vaismaa M., Vanninen P., Koskela H.

Phytochem. Anal., 27 (2016) 64–72.

Chemical Munitions Search & Assessment—An evaluation of the dumped munitions problem in the Baltic Sea

Bełdowski, J., Klusek, Z., Szubska, M., Turja, R., Bulczak, A.I., Rak, D., Brenner, M., Lang, T., Kotwicki, L., Grzelak, K., Jakacki, J., Fricke, N., Östin, A., Olsson, U., Fabisiak, J., Garnaga, G., Rattfelt Nyholm, J., Majewski, P., Broeg, K., Söderström, M., Vanninen, P., Popiel, S., Nawała, J., Lehtonen, K., Berglind, R., Schmidt, B.

Deep Sea Research Part II (2015), doi:10.1016/j.dsr2.2015.01.017.

 

Arsenic concentration in Baltic Sea sediments close to chemical munition dumpsites

Bełdowski, J., Szubska, M., Emelyanov, E., Garnaga, G., Drzewinska, A., Beldowska, M., Vanninen, P., Östin, A., Fabisiak, J.

Deep Sea Research Part II (2015), doi:10.1016/j.dsr2.2015.03.001.

 

Applying human and pig hepatic in vitro experiments for sulfur mustard study: Screening and identification of metabolites by liquid chromatography–tandem mass spectrometry

Halme M., Pesonen M., Hakala U., Pasanen M., Vähäkangas K., Vanninen P.

Rapid Commun.Mass Spectrom., 29 (2015) 1279-1287.

 

Analysis of nitromethane from chloropicrin exposed in vitro samples by validated stable isotope dilution HS-GC-MS method.

Halme M., Pesonen M., Grandell T., Kuula M., Pasanen M., Vähäkangas K., Vanninen P.

J. Sep. Sci., 38 (2015) 3383–3389.

 

Results of a Saxitoxin Proficiency Test Including Characterization of Reference Material and Stability Studies

Harju, K., Rapinoja, M.-L., Avondet, M.-A., Arnold, W., Schär, M., Luginbühl, W., Kremp A., Suikkanen, S., Kankaanpää, H., Burrell, S.; Söderström, M. and Vanninen P.

Toxins, 2015, 7, 4852–4867.

 

Optimization of Sample Preparation for the Identification and Quantification of Saxitoxin in Proficiency Test Mussel Sample using Liquid Chromatography-Tandem Mass Spectrometry

Harju, K., Rapinoja, M.-L., Avondet, M.-A., Arnold, W., Schär, M., Burrell, S., Luginbühl, W., Vanninen, P.A.

Toxins, 2015, 7, 4868–4880.

 

Characterization of Ricin and R. communis Agglutinin Reference Materials

Worbs S., Skiba S., Söderström M.,  Rapinoja M.-L., Zeleny R.,  Russmann H., Schimmel H., Vanninen P.,  Fredriksson, S.-Å., Dorner, B.G.

Toxins, 2015, 7, 4906-4934.

CHEMSEA Findings

Jacek Bełdowski, Jacek Fabisiak, Stanisław Popiel, Anders Östin, Ulf Olsson, Paula Vanninen, Anu Lastumäki, Thomas Lang, Nicolai Fricke, Matthias Brenner, Rune Berglind, Janina Baršiene, Zygmunt Klusek, Bartłomiej Pączek, Martin Söderström, Kari Lehtonen, Marta Szubska, Galina Garnaga, Vitalijus Malejevas, Harri Koskela, Jarosław Michalak, Raisa Turja, Mia Halme, Thomas Sandström ,Ulf Bickmeyer, Katja Broeg, Dzenan Sahovic, Adam Olejnik, Jan Fidler

Institute of Oceanology Polish Academy of Sciences, Gdańsk, 86pp, ISBN : 978-83-936609-1-9.

 

Determination of mustard gas hydrolysis products thiodiglycol and thiodiglycol sulfoxide by gas chromatography-tandem mass spectrometry after trifluoroacetylation

S. Popiel, J. Nawala, D. Dziedric, M. Söderström, P. Vanninen

Anal. Chem. 86, 2014, 5865-5872.

 

Rapid Chemical Characterisation of Stilbenes in the Root Bark of Norway Spruce by Off-line HPLC/DAD–NMR

Daniel Girma Mulat, Harri Latva-Mäenpää, Harri Koskela, Pekka Saranpää and Kristiina Wähälä

Phytochem Anal. 25, 529-536 (2014).

Saxitoxin Analysis

Mia Halme, Paula Vanninen

Encyclopedia of Analytical Chemistry, Published Online: 15 March 2013, DOI: 10.1002/9780470027318.a9320

 

Significance of heme-based respiration in meat spoilage caused by Leuconostoc gasicomitatum

Jääskeläinen, E., Johansson, P., Kostiainen, O., Nieminen, T., Schmidt, G., Somervuo, P., Mohsina, M., Vanninen, P., Auvinen, P.and Björkroth, J.

Applied and Environmental Microbiology, 2013, 79( 4), 1078-1085.

 

Methodology for National Risk Analysis and Prioritization of Toxic Industrial Chemicals

Piia Taxell, Kerstin Engström, Juha Tuovila, Martin Söderström, Harri Kiljunen, Paula Vanninen and Tiina Santonen

Journal of Toxicology and Environmental Health, Part A:, 76:690-700, 2013.

Verification and quantification of saxitoxin from algal samples using fast and validated hydrophilic interaction liquid chromatography–tandem mass spectrometry method

Mia Halme, Marja-Leena Rapinoja, Maaret Karjalainen, Paula  Vanninen

J. Chromatogr. B, 880 (2012) 50-57.

 

A set of triple-resonance nuclear magnetic resonance experiments for structural characterization of organophosphorus compounds in mixture samples

Harri Koskela

Anal. Chim. Acta, 751 (2012) 105-111.

Verification and quantification of saxitoxin from algal samples using fast and validated hydrophilic interaction liquid chromatography–tandem mass spectrometry method

M. Halme, M.-L. Rapinoja, M. Karjalainen, P. Vanninen.

J. Chromatogr. B (2011) DOI:/10.1016/j.jchromb.2011.11.015 (in press).

 

Development and validation of efficient stable isotope dilution LC-HESI-MS/MS method for the verification of β-lyase metabolites in human urine after sulfur mustard exposure

Mia Halme, Maaret Karjalainen, Harri Kiljunen, Paula Vanninen

J. Chromatogr. B, 879 (2011) 908–914.

 

Gas Chromatography in Screening of Chemicals Related to the Chemical Weapons Convention

Olli Kostiainen

Encyclopedia of Analytical Chemistry: Chemical Weapons Chemicals Analysis, ed. R.A. Meyers, John Wiley, Chichester, 15 June 2010, DOI:/10.1002/9780470027318.a0412.pub2.

 

Verification of Chemicals Related to the Chemical Weapons Convention

P. Vanninen

Encyclopedia of Analytical Chemistry, eds R.A. Meyers, John Wiley: Chichester. DOI: 9780470027318.a0401.pub2. Published December 15, 2011.

 

Separation and structural characterization of a synthetic cannabinoid found in a herbal product using off-line LC-DAD-NMR

Harri Koskela, Ullastiina Hakala, Paula Vanninen, Ilmari Szilvay

Anal. Methods, 3 (2011) 2307–2312.

 

Biomarkkerit inkapasitoivien ja ärsyttävien yhdisteiden tunnisteina

M. Pesonen, T. Kuitunen, M. Halme, P. Vanninen, H. Seulanto, M. Hemmilä, M. Pasanen, K. Vähäkangas

Ann. Med. Milit. Fenn. (2011) 86(2) 9-12.

 

Blue Book, 2011 Edition, “Recommended Operating Procedures for Analysis in the Verification of Chemical Disarmament”

Paula Vanninen

The Ministry for Foreign Affairs of Finland, University of Helsinki, ISBN 978-952-10-7407-3 (paperback), ISBN 978-952-10-7408-0 (PDF).

 

Development and validation of efficient stable isotope dilution LC-HESI-MS/MS method for the verification of beta-lyase metabolites in human urine after sulfur mustard exposure

Mia Halme, Maaret Karjalainen, Harri Kiljunen, Paula Vanninen

J. Chrom. B, 2011, DOI:10.1016/j.jchromb.2011.02.043

Structural characterization of chemical warfare agent degradation products in decontamination solutions with proton band-selective 1H–31P NMR spectroscopy

Harri Koskela, Ullastiina Hakala and Paula Vanninen

Anal. Chem. 82 (2010) 5331-5340.

 

Tetradecyl(trihexyl)phosphonium chloride ionic liquid single-drop microextraction for electrothermal atomic absorption spectrometric determination of lead in water samples

Estefanía M. Martinisa, Paula Bertóna, Jorgelina C. Altamiranoa, Ullastiina Hakala and Rodolfo G. Wuillouda

Talanta 80 (2010) 2034–2040.

 

Use of NMR techniques for toxic organophosphorus compound profiling

Harri Koskela

J. Chromat. B, Special issue: Bioanalysis of Organophosphorus Toxicants and Corresponding Antidotes”, 878 (2010). 1365–1381.

 

Quantitative two-dimensional HSQC experiment for high magnetic field NMR spectrometers

Harri Koskela, Outi Heikkilä, Ilkka Kilpeläinen and Sami Heikkinen

J. Magn. Reson. 202(2010) 24–33.

 

Hazardous substances in the Baltic Sea: An integrated thematic assessment of hazardous sub-stances in the Baltic Sea

Martin Söderström and Paula Vanninen, Paragraph, Dumped chemical munitions pages 109-110 in Korpinen, S. (ed.), Laamanen, M. (ed.), Andersen, J.H., Asplund, L., Berger, U., Bignert, A., Boalt, E., Broeg, K., Brzozowska, A., Cato, I., Durkin, M., Garnaga, G., Gustavson, K., Haarich, M., Hedlund, B., Köngäs, P., Lang, T., Larsen, M.M., Lehtonen, K., Mannio, J., Mehtonen, J., Murray, C., Nielsen, S., Nyström, B., Pazdro, K., Ringeltaube, P., Schiedek, D., Schneider, R., Stankiewicz, M., Strand, J., Sundelin, B., Söder-ström, M. T., Vallius, H., Vanninen, P., Verta, M., Vieno, N., Vuorinen, P.J., Zahharov, A.

Baltic Sea Environment Proceedings 120B, .Helsinki Commission, pp. 116.

 

Environmental Hazards of Sea-Dumped Chemical Weapons - Does the post-WWII burial at sea of chemical weapons still pose a human and environmental risk?

Hans Sanderson, Patrik Fauser, Marianne Thomsen, Paula Vanninen, Martin Soderstrom, Yuri Savin, Ildus Khalikov, Anu Hirvonen, Susa Niiranen, Tine Missiaen, Alexander Gress, Pavel Borodin, Nadezda Medvedeva, Yulia Polyak, Vadim Paka, Victor Zhurbas, Pascal Feller

Environ. Sci. Technol. 44 (2010) 4389–4394

 

Evaluation of a chemical munition dumpsite in the Baltic Sea based on geophysical and chemical investigations

Tine Missiaen, Martin Söderström, Irina Popescu, Paula Vanninen

Sci. Total Environ. 408 (2010) 3536–3553.

 

Akkreditoinnin hyödyntäminen uusilla alueilla - näkemyksiä akkreditointikelpoisuudesta

Matti Lanu, Marja-Leena Kuitunen, Eeva-Liisa Hartikainen, Jouko Roine, Marja-Leena Kantanen, Christina Waddington, Marjukka Mäkinen

Arviointiperiaateopas A7, Finas Akkredtointipalvelu, 01.06.2010.

 

Sample Preparation for Analysis of Chemicals Related to the Chemical Weapons Convention in an Off-site Laboratory

Marja-Leena Kuitunen

Encyclopedia of Analytical Chemistry: Chemical Weapons Chemicals Analysis, ed. R.A. Meyers, John Wiley, Chichester, 15 December 2010, DOI: 10.1002/9780470027318.a0410.pub2.

 

Capsaicinoids, chloropicrin and sulfur mustard: Possibilities for exposure biomarkers

Maija Pesonen, Kirsi Vähäkangas, Mia Halme, Paula Vanninen, Heikki Seulanto, Matti Hemmilä, Markku Pasanen, Tapio Kuitunen

Frontiers in Predictive Toxicity, 2010, DOI:10.3389/fphar.2010.00140.

On-flow pulsed field gradient heteronuclear correlation spectrometry in off-line LC−SPE−NMR analysis of chemicals related to the Chemical Weapons Convention

Harri Koskela, Mia Ervasti, Heikki Björk and Paula Vanninen

Anal. Chem. 81, 1262-1269 (2009).

 

1H, 13C and 15N resonance assignments of the human filamin A tandem immunoglobulin-like domains 16–17 and 18–19

Outi Heikkinen, Perttu Permi, Harri Koskela, Jari Ylänne and Ilkka Kilpeläinen

Biomol. NMR Assign. 3, 53-56 (2009).

 

Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA - Implications for the catalytic mechanism of parvulins

Outi Heikkinen, Raili Seppälä, Helena Tossavainen, Sami Heikkinen, Harri Koskela, Perttu Permi and Ilkka Kilpeläinen

BMC Struct. Biol. 9(17), DOI:10.1186/1472-6807-9-17 (2009).

 

Solution structure of the first immunoglobulin domain of human myotilin

Outi Heikkinen, Perttu Permi, Harri Koskela, Olli Carpén, Jari Ylänne and Ilkka Kilpeläinen

J. Biomol. NMR 44, 107-112 (2009).

 

Quantitative 2D NMR studies

Harri Koskela

Ann. Rep. NMR Spectrosc. 66, 1-31 (2009).

 

Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin

Outi K. Heikkinen, Salla Ruskamo, Peter V. Konarev, Dmitri I. Svergun, Tatu Iivanainen, Sami M. Heikkinen, Perttu Permi, Harri Koskela, Ilkka Kilpeläinen, and Jari Ylänne

J. Biol. Chem. 284, 25450-25458 (2009).

 

Nuclear magnetic resonance spectroscopy in analysis of chemicals related to the Chemical Weapons Convention

Markku Mesilaakso, Urs Meier, and Harri Koskela

Encyclopedia of Analytical Chemistry: Chemical Weapons Chemicals Analysis, DOI: 10.1002/9780470027318.a0409.pub2 (2009).

NMR properties of conjugated linoleic acid (CLA) methyl ester hydroperoxides

Taina I. Pajunen, Harri Koskela, Tapio Hase, and Anu Hopia

Chem. Phys. Lipids 154, 105-144 (2008).

 

Application of a Microcoil Probe Head in NMR Analysis of Chemicals Related to the Chemical Weapons Convention

Harri Koskela and Paula Vanninen

Anal. Chem. 80, 5556-5564 (2008).

Continuous H/D exchange of aromatic hydrocarbons using near-critical deuterium oxide

Boris Kerler, Jaroslav Pól, Kari Hartonen, Martin T. Söderström, Harri T. Koskela, and Marja-Liisa Riekkola

J. Supercritical Fluids 39, 381–388 (2007)

 

Hafnium Bis(phenoxyimino) Dibenzyl Complexes and Their Activation toward Olefin Polymerization

Kirill V. Axenov, Martti Klinga, Olli Lehtonen, Harri T. Koskela, Markku Leskelä, and Timo Repo

Organometallics 26, 1444-1460 (2007)

 

Rapid and Accurate Processing Method for Amide Proton Exchange Rate Measurement in Proteins

Harri Koskela, Outi Heikkinen, Ilkka Kilpeläinen, and Sami Heikkinen

J. Biomol. NMR 37, 313–320 (2007)

 

Determination of Trace Amounts of Chemical Warfare Agent Degradation Products in Decontamination Solutions with NMR Spectroscopy

Harri Koskela, Marja-Leena Rapinoja, Marja-Leena Kuitunen, and Paula Vanninen

Anal. Chem. 79, 9098-9106 (2007)

Screening and Identification of Organophosphorus Compounds Related to the Chemical Weapons Convention with 1D and 2D NMR Spectroscopy

Harri Koskela, Nicoleta Grigoriu, and Paula Vanninen

Anal. Chem. 2006, 78, 3715-3722.

 

Insertion of Noble Gas Atoms into Cyanoacetylene: Ab Initio and Matrix Isolation Study

Leonid Khriachtchev, Antti Lignell, Hanna Tanskanen, Jan Lundell, Harri Kiljunen and Markku Räsänen

J.Phys.Chem A 2006, 110(42), 11876-11885.

Some Aspects of Quantitative 2D NMR

Koskela H, Kilpeläinen I & Heikkinen S

J Magn Reson 174: 237-244. (2005)

 

Analysis Strategy for Analysis of Chemicals Related to the Chemical Weapons Convention in an Off-site Laboratory

Markku Mesilaakso

Chemical Weapons Convention Chemicals Analysis; Sample Collection, Preparation and Analytical Methods, M. Mesilaakso (Ed.), Wiley & Sons, 2005, 151-162.

 

Sample Preparation for Analysis of Chemicals Related to the Chemical Weapons Convention in an Off-site Laboratory

Marja-Leena Kuitunen

Chemical Weapons Convention Chemicals Analysis; Sample Collection, Preparation and Analytical Methods, M. Mesilaakso (Ed.), Wiley & Sons, 2005, 163-184.

 

Gas Chromatography in Screening of Chemicals Related to the Chemical Weapons Convention

Olli Kostiainen

Chemical Weapons Convention Chemicals Analysis; Sample Collection, Preparation and Analytical Methods, M. Mesilaakso (Ed.), Wiley & Sons, 2005, 185-249.

 

Nuclear Magnetic Resonance Spectroscopy in Analysis of Chemicals Related to the Chemical Weapons Convention in an Off-site Laboratory

Markku Mesilaakso and Andreas Niederhauser

Chemical Weapons Convention Chemicals Analysis; Sample Collection, Preparation and Analytical Methods, M. Mesilaakso (Ed.), Wiley & Sons, 2005, 321-352.

 

Fourier Transform Infrared Spectroscopy in Analysis of Chemicals Related to the Chemical Weapons Convention in an Off-site Laboratory

Martin T. Söderström

Chemical Weapons Convention Chemicals Analysis; Sample Collection, Preparation and Analytical Methods, M. Mesilaakso (Ed.), Wiley & Sons, 2005, 353-386.

 

A 100 kDa urinary protein associates with insulin resistance in offsprings of type 2 diabetic patients

A. Pätäri, P. Karhapää, H. Taipale, U. Salmenniemi, E. Ruotsalainen, P. Vanninen, H. Holthöfer and M. Laakso

Diabetologia, 48 (2005) 1844.

CAGEBIRD: Improving the GBIRD Filter with a CPMG Sequence

Harri Koskela, Ilkka Kilpeläinen, Sami Heikkinen

Journal of Magnetic Resonance (2004), 170, 121-126.

 

Preparation of fluorine-18-labeled fluoromisonidazole using two different synthesis methods

Eeva-Liisa Kämäräinen, Teija Kyllönen, Outi Nihtilä, Heikki Björk and Olof Solin

Journal of Labelled compounds and Radiopharmaceuticals 47 (2004) 37–45.

A Gate to Organokrypton Chemistry: HKrCCH

Leonid Khriachtchev, Hanna Tanskanen, Arik Cohen, Benny Gerber, Jan Lundell, Mika Petterson, Harri Kiljunen, Markku Räsänen

J. Am. Chem. Soc., 125 (2003) 6876–6877.

 

Fluorine-Free Organoxenon Chemistry: HXeCCH, HxeCC and HXeCCXeH

Leonid Khriachtchev, Hanna Tanskanen, Jan Lundell, Mika Petterson, Harri Kiljunen, Markku Räsänen

J. Am. Chem. Soc., 125 (2003) 4696–4697.

 

Chemical compounds formed from diacetylene and rare-gas atoms: HKrC4H and HXeC4H

Hanna Tanskanen, Leonid Khriachtchev, Jan Lundell, Harri Kiljunen, Markku Räsänen

Journal of the American Chemical Society (2003), 125(52), 16361-6.

The incorporation of 3,4-dichloroaniline, a pesticide metabolite, into dehydrogenation polymers of coniferyl alcohol (DHPs). Part 2. Identification of a dimeric adduct

Grösta Brunow, Sanni Raskila, Heikki Björk

Holzforschung (2002), 56(1), 73-75.

Regioselectivity of Methylation of O-Demethylangolensin [1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one]. An Expedient Synthesis of Angolensin

Kristiina Wähälä, Tuija Jokela, Auli Salakka, Seppo Kaltia,  Markku Mesilaakso

J. Chem. Soc., Perkin Trans. 1 (2001), 642-644.

The Identification of Dilignols from Dehydrogenation Mixtures of Coniferyl Alcohol and Apocynol [4-(1-Hydroxyethyl)-2-methoxyphenol] by LC-ES-MS/MS

Kaisa Syrjänen, Jussi Sipilä, Heikki Björk, Gösta Brunow

Journal of Agricultural and Food Chemistry (2000), 48(11).

 

Two-dimensional TLC separation and mass spectrometric identification of anthraquinones isolated from the fungus Dermocybe sanguinea

Riikka Räisänen, Heikki Björk, Paavo H Hynninen

Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2000), 55(3/4), 195-202.

 

Analysis of 1H and 13C{1H} NMR Spectral Parameters and Geometries of Three Isomeric Diphenylbicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydrides

Mariitta Kokko, Markku Mesilaakso, Aarne Pajunen

Spectroscopy Letters 33 (2000), 717-734.

Chrystallographic and NMR Analyses of 9-Phenylthiohenanthrene and 9-t-Butylthiophenanthrene

Kaija Sipilä, Jarno Kansikas, Markku Mesilaakso

J. Chem. Soc., Perkin Trans. 2 (1999), 1841-1845.

Analysis of NMR-spectral Parameters and Molecular Dynamics Study of 3-Quinuclidinol and 3-Quinuclidinyl Benzilate

Sami Heikkinen, Markku Mesilaakso, Erkki Rahkamaa

Magn. Reson. Chem. (1998), 36, 627-634.

Analysis of volatile organic compounds in air using retention indices together with a simple thermal desorption and cold trap method

Eeva Kivi-Etelätalo, Olli Kostiainen, Mariitta Kokko

Journal of Chromatography, A (1997), 787(1 + 2), 205-214.

 

The Synthesis, Structure and Anticancer Activity of cis- and trans-4',7-Dihydroxyisoflavan-4-ols

Kristiina Wähälä, Jorma K. Koskimies, Markku Mesilaakso, Auli K. Salakka, Tero K. Leino, Herman Adlercreutz

J. Org. Chem. (1997), 62, 7690-7693.

Fragmentation of protonated O,O-diethyl O-aryl phosphorothionates in tandem mass spectral analysis

Tuula Kuivalainen, Risto Kostiainen, Rolf Uggla, Markku Sundberg, Heikki Björk

Journal of the American Society for Mass Spectrometry (1996), 7(2), 189-97.

 

Isolation and Structure Elucidation of the Main Photodecomposition Product of Trichloromethiazide

Veikko Ulvi, Markku Mesilaakso, Jorma Matikainen

Pharmazie (1996), 51, 774-775.

Fragmentation of protonated O,O-dimethyl O-aryl phosphorothionates in tandem mass spectral analysis

Tuula Kuivalainen, Risto Kostiainen, Rolf Uggla, Markku Sundberg, Heikki Björk

Journal of the American Society for Mass Spectrometry (1995), 6(6), 488-97.

 

Structure Elucidation of 6-Chloro-2-methyl-4(1H)-quinazolinone, a Photodecomposition Product of Midazolam

Riitta Andersin, Markku Mesilaakso

J. Pharm. Biomed. Anal. (1995), 13, 667-670.