Publications

The latest representative publications of research conducted in the ONCOSYS groups:

 

Olli Carpen:
BRAF immunohistochemistry predicts sentinel lymph node involvement in intermediate thickness melanomas.
Manninen AA, Gardberg M, Juteau S, Ilmonen S, Jukonen J, Andersson N, Carpén O.
PLoS One. 2019 Apr 30;14(4):e0216043. doi: 10.1371/journal.pone.0216043. eCollection 2019. PMID: 31039200

Anniina Färkkilä:
Single-Arm Phases 1 and 2 Trial of Niraparib in Combination With Pembrolizumab in Patients With Recurrent Platinum-Resistant Ovarian Carcinoma.
Konstantinopoulos PA, Waggoner S, Vidal GA, Mita M, Moroney JW, Holloway R, Van Le L, Sachdev JC, Chapman-Davis E, Colon-Otero G, Penson RT, Matulonis UA, Kim YB, Moore KN, Swisher EM, Färkkilä A, D'Andrea A, Stringer-Reasor E, Wang J, Buerstatte N, Arora S, Graham JR, Bobilev D, Dezube BJ, Munster P.
JAMA Oncol. 2019 Jun 13. doi: 10.1001/jamaoncol.2019.1048. [Epub ahead of print] PMID: 31194228

Sampsa Hautaniemi:
Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer.
Oikkonen J, Zhang K, Salminen L, Schulman I, Lavikka K, Andersson N, Ojanperä E, Hietanen S, Grénman S, Lehtonen R, Huhtinen K, Carpén O, Hynninen J, Färkkilä A, Hautaniemi S.
JCO Precision Oncology. 2019 May 3;3, 1-12. DOI: 10.1200/PO.18.00343

Liisa Kauppi:
A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients.
Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Vähärautio A, Grénman S, Carpén O, Kauppi L.
Clin Cancer Res. 2018 Sep 15;24(18):4482-4493. doi: 10.1158/1078-0432.CCR-17-3770. Epub 2018 Jun 1. PMID: 29858219

Riitta Lassila:
Phenotypic characterization of haemophilia B - Understanding the underlying biology of coagulation factor IX.
Tjärnlund-Wolf A, Lassila R.
Haemophilia. 2019 Jul;25(4):567-574. doi: 10.1111/hae.13804. Epub 2019 Jun 10. Review. PMID: 31180618

Johan Lundin:
Fast and accurate medication identification.
Larios Delgado N, Usuyama N, Hall AK, Hazen RJ, Ma M, Sahu S, Lundin J.
NPJ Digit Med. 2019 Feb 28;2:10. doi: 10.1038/s41746-019-0086-0. eCollection 2019. PMID:31304359

Tuomas Mirtti:
New prostate cancer grade grouping system predicts survival after radical prostatectomy.
Erickson A, Sandeman K, Lahdensuo K, Nordling S, Kallajoki M, Seikkula H, Bützow A, Vasarainen H, Boström PJ, Taimen P, Rannikko A, Mirtti T.
Hum Pathol. 2018 May;75:159-166. doi: 10.1016/j.humpath.2018.01.027. Epub 2018 Feb 13. No abstract available. PMID: 29447924

Antti Mäkitie:
Low-phase angle in body composition measurements correlates with prolonged hospital stay in head and neck cancer patients.
Lundberg M, Dickinson A, Nikander P, Orell H, Mäkitie A.
Acta Otolaryngol. 2019 Apr;139(4):383-387. doi: 10.1080/00016489.2019.1566779. Epub 2019 Mar 22. PMID: 30900483

Antti Rannikko:
MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis.
Kasivisvanathan V, Rannikko AS, Borghi M, Panebianco V, Mynderse LA, Vaarala MH, Briganti A, Budäus L, Hellawell G, Hindley RG, Roobol MJ, Eggener S, Ghei M, Villers A, Bladou F, Villeirs GM, Virdi J, Boxler S, Robert G, Singh PB, Venderink W, Hadaschik BA, Ruffion A, Hu JC, Margolis D, Crouzet S, Klotz L, Taneja SS, Pinto P, Gill I, Allen C, Giganti F, Freeman A, Morris S, Punwani S, Williams NR, Brew-Graves C, Deeks J, Takwoingi Y, Emberton M, Moore CM; PRECISION Study Group Collaborators.
N Engl J Med. 2018 May 10;378(19):1767-1777. doi: 10.1056/NEJMoa1801993. Epub 2018 Mar 18. PMID: 29552975

Jing Tang: 
DrugComb: an integrative cancer drug combination data portal
Zagidullin, B., Aldahdooh, J. M. F., Zheng, S., Wang, W., Wang, Y., Saad, J., Malyutina, A., Jafari, M., Tanoli, Z-R., Pessia, A. & Tang, J., 8 May 2019, In : Nucleic Acids Research. doi: 10.1093/nar/gkz337

Anna Vähärautio:
Cancer by super-enhancer.
Vähärautio A, Taipale J.
Science. 2014 Dec 12;346(6215):1291-2. doi: 10.1126/science.aaa3247. No abstract available. PMID: 25504702

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