In Iwai lab our research is focused on the biophysical and structural information of proteins. Our main tools for studying the dynamics and structure of proteins are NMR spectroscopy and X-ray crystallography. Focal points of study are protease- and protein splicing- mediated ligation, protein designs and structure-based protein engineering. Overall, we are trying to understand how inteins came to exist, what biological functions they have, and how this knowledge could be applied biotechnologically.
Main subjects of study
Read more about NMR, X-ray crystallography and the recent subjects of study
NMR spectroscopy can provide 3D structures of proteins, and additionally infromation on proteins at atomic resolution, for example protein...
Ultimately, we study the biophysical and structural features of proteins to achieve information for structure-based protein engineering,...
Since we study protein functions on an atomic level, x-ray crystallography is a useful tool to study the 3D positions of atoms in the...