In Iwai lab our research is focused on the biophysical and structural information of proteins. Our main tools for studying the dynamics and structure of proteins are NMR spectroscopy and X-ray crystallography. Focal points of study are protease- and protein splicing- mediated ligation, protein designs and structure-based protein engineering. Overall, we are trying to understand how inteins came to exist, what biological functions they have, and how this knowledge could be applied biotechnologically.