Stop PREP to stop neurodegeneration?

We are studying the role of prolyl oligopeptidase (PREP, formerly known as POP) on disease progression and neuronal toxicity in neurodegenerative disorders with protein aggregation. These disorders include several serious diseases such as Alzheimer’s and Parkinson’s diseases, and several more rare neurodegenerative conditions. Based on PREP inhibitors, we are developing novel and disease-modifying drug therapies to stop neuronal death in Alzheimer's and Parkinson's diseases.
Find out more about PREP research

Our research

Interested in collaborating with us or investing in our novel PREP ligands? See the video below for more information!

NeuroPREP pitch fall 2020

This 5-minute video briefly outlines our research and provides details on how to progress the novel PREP ligands into clinical trials.


Recent news from PREP lab

Kun männyn pihkan terpenoidin johdannainen yhdistetään koivun #nanoselluloosa'an syntyy…

First paper of year 2021 is out! This was a difficult one but we managed to show that #PREP regulates dopamine tran……

Our former PhD student, Dr. Ulrika Julku, studied the role of #prolyloligopeptidase in dopamine transporter functio……

Tämä käyrä on järkyttävä. Ruotsin valtio käyttää 2019 budjetistaan 20% enemmän tutkimukseen kuin 2007. Tanska melke……