Our laboratory is focused upon three major topics, and we take advantage of both yeast and human cell culture. First, we examine how proteins synthesized by the cell make their way to mitochondria and peroxisomes. Second, we have developed a keen interest in understanding organellar evolution. Specifically, we focus upon selection within the mitochondrial genome and upon events that occurred during conversion of the proto-mitochondrial endosymbiont to an organelle. Third, we study the consequences of organelle damage at the cellular level. One long term aim of our laboratory is to help develop treatments for metabolic disease.
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@CoryDunnMitoUH

Researchers have had great success using genomics to identify the genetic causes of rare diseases. In 1990, scienti… twitter.com/i/web/status/1…

SignalP 6.0 achieves signal peptide prediction across all types using protein language models biorxiv.org/cgi/content/sh… #bioRxiv

Do you really need 64 codons? Reducing the genetic code and tRNA repertoire of E. coli to decode 61 of the possib… twitter.com/i/web/status/1…

A really extraordinary piece of writing. It has been required reading for first year grad students at @uwgenome for… twitter.com/i/web/status/1…