McWilliams TG*, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar S, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK*. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biology 8: 180108, 2018. Article selected for Journal Cover Image
Suomi F, McWilliams TG. Autophagy in the mammalian nervous system: a primer for neuroscientists. Neuronal Signaling 3: NS20180134, 2019. Article selected for Journal Cover Image
Muha V, Williamson R, Hills R, McNeilly AD, McWilliams TG, Alonso J, Schimpl M, Leney AC, Heck AJR, Sutherland C, Read KD, McCrimmon RJ, Brooks SP, van Aalten DMF. Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice. Open Biology 9: 190192, 2019.
Howard L, McWilliams TG, Wyatt S, Davies AM. CD40 forward signalling is a physiological regulator of early sensory axon growth. Development 146: dev176495, 2019.
Long M, McWilliams TG. Monitoring autophagy in cancer: From bench to bedside. Seminars in Cancer Biologyin press, 2019.
McWilliams TG, Prescott AR, Villarejo-Zori B, Ball G, Boya P, Ganley IG. A comparative map of macroautophagy and mitophagy in the vertebrate eye. Autophagy 15: 1296-1308, 2019.
McWilliams TG*, Suomalainen A*. Mitochondrial DNA can be inherited from fathers, not just mothers. Nature 565: 296-297, 2019.
McWilliams TG, Ganley IG. Investigating mitophagy and mitochondrial morphology in vivo using mito-QC: a comprehensive guide. Methods Mol Biol 1880: 621-642, 2019.
Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J. PGC-1β modulates statin-associated myotoxicity in mice. Archives of Toxicology 93: 487-504, 2019.
2018
McWilliams TG*, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar S, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK*. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biology 8: 180108, 2018.
McWilliams TG*, Prescott AR, Montava-Garriga L, Ball G, Singh F, Barini E, Muqit MMK, Brooks SP, Ganley IG*. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metabolism 27: 439-449, 2018.
Rodger CE, McWilliams, Ganley IG. Mammalian mitophagy - from in vitro molecules to in vivo models. FEBS Journal 285: 1185-1202, 2018.
2017
McWilliams TG, Howard L, Wyatt S, Davies AM. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatalprojection in vivo. Experimental Neurology 298: 97-103, 2017.
McWilliams TG, Muqit MMK. PINK1 and Parkin: emerging themes in mitochondrial homeostasis. Current Opinion in Cell Biology 45: 83-91, 2017.
2016
McWilliams TG, Ganley IG. Life in lights: Tracking mitochondrial delivery to lysosomes in vivo. Autophagy 12: 2506-2507, 2016.
Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T. UBQLN2 mediates autophagy-independent progein aggregate clearance by the proteasome. Cell 166: 935-949, 2016.
McWilliams TG, Prescott AR, Allen GF, Tamjar J, Munson MJ, Thomson C, Muqit MM, Ganley IG. mito-QC illuminates mitophagy and mitochondrial architecture in vivo. Journal of Cell Biology 214: 333-345, 2016.
2015
McWilliams TG, Howard L, Wyatt S, Davies AM. Regulation of autocrine signaling in subset of sympathetic neurons has regional effects on tissue innervation. Cell Reports 10: 1443-1449, 2015.