Research

Our group is focused on the genetic and hormonal regulation of growth and development: we want to find out what launches puberty and which factors regulate growth, sexual development, and the function of the pituitary gland.

We develop new diagnostic and treatment strategies to patients with delayed puberty by modeling the mechanisms of genetic diseases with human pluripotent stem cells and mice.

The main techniques employed are

  • Genomic editing of human pluripotent stem cells with CRISPR/CAS9
  • Stem cell maintenance and differentiation
  • FACS, WB, IF, qPCR, ELISA, NGS, etc.