Our research is conducted in three centers in Finland (Helsinki, Vaasa and Jakobstad) and in Malmö, Sweden.
Centers & People
Botnia Study's research activities in Helsinki (study visits, laboratory work) take place in Biomedicum Helsinki that is located at the Meilahti hospital area.
In Helsinki, Botnia Study's activities are a collaboration between University of Helsinki (Research Programs' Unit/ CAMM and Institute for Molecular Medicine Finland, FIMM), Folkhälsan Research Center and HUS Abdominal Center, Department of Endocrinology.
Botnia Study is part of the Academy of Finland Centre of Excellence in Complex Disease Genetics - from Discovery to Precision Medicine (2018-2025). The Academy of Finland’s Centres of Excellence (CoE) are at the very cutting edge of science in their fields.
Tiinamaija Tuomi, MD, PhD, Docent
Tiinamaija Tuomi leads Botnia Study together with Prof. Leif Groop. She works as a Chief Departmental Physician at the Department of Endocrinology, Helsinki University Hospital. She is a group leader at Folkhälsan Research Centre and a research director at Institute for Molecular Medicine Finland (FIMM), University of Helsinki. In addition, she is a vice-director of the “Centre of Excellence of Complex Disease Genetics – from discovery to translation” (FIMM 2018-2025).
Leif Groop, MD, PhD, Professor
Leif Groop is the founder and co-director of Botnia Study. He is a Professor (emeritus) in Endocrinology at Lund University and research director at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki.
Liisa Hakaste, MD, PhD, specialist in internal medicine and endocrinology
Postdoctoral fellow, Clinical Coordinator
Liisa hakaste has defended her thesis at Imperial College London, University of London. In Botnia Study she works as a Post-doc researcher and clinical coordinator, special interest in PPP-Botnia, hypoglycemia and phenotypes of the new diabetes subgroups.
Jarno Kettunen, MD
Doctoral student, coordinator of the FinnMody study
Jarno Kettunen is a medical doctor graduated in 2014. He runs the MODY related PhD project FinnMODY.
Mikko Lehtovirta, MD, PhD
Postdoctoral fellow (FIMM), Coordinator of the Botnia Zinc- and iPSC-studies
In his research, Mikko Lehtovirta focuses on metabolic human studies with individuals and families with special emphasis on skeletal muscle insulin mediated glucose metabolism and pancreatic insulin secretion.
Om Dwivedi, PhD
Vasudha Ahuja, MBBS, MPH, PhD
Vasudha Ahuja is a Postdoctoral fellow at the Center of Excellence in Complex Disease Genetics (CoECDG), FIMM. She obtained her PhD in epidemiology from the University of Pittsburgh, US in 2015. During her PhD, she conducted research on ethnic disparities between Whites and Japanese related to markers of type 2 diabetes and subclinical cardiovascular disease. Currently, she is studying the accuracy of glucose traits of OGTT in diagnosing type 2 diabetes as a part of an international multi-center project.
Minna Harsunen, M.D., Ph.D., pediatrics
In her research, Minna Harsunen focuses on characterization of autoantibody negative pediatric diabetic patients and defining subgroups of type 1 diabetes: evaluation of the beta-cell function and progression of insulin deficiency and genetic characterization of patients within the FinnMODY-project. In addition, she examines the role of a mild pancreatitis in the pathogenesis of type 1 diabetes.
Iiro Karhiaho, MD
Paula Kokko, medical laboratory technologist
Paula Kokko works as a laboratory manager in the Botnia Study. She coordinates all the Botnia centers’ laboratory work, sample handling and logistics from Helsinki.
Laura Impivaara, MSSc
Research administration coordinator
Laura Impivaara’s duties include variety of tasks concerning research administration, such as assisting with the grant applications, permission procedures (ethical approvals, study permissions) and data acquisition applications from the register authorities. In addition, she is responsible for HR assistance within the group and financial project management.
Stina Uusitalo, nurse
Stina Uusitalo works as a study nurse at the Helsinki Botnia-center. She is responsible for the recruitment of study participants and study visits especially for the FinnMody and PPP2 projects in Helsinki.
Medical students and research assistants:
Peik Pietilä, B.M.
Iina Elfving, B.M.
Karolina Kivimäki, medical student, Research Assistant
Emmi Saksela, medical student, Research Assistant
Botnia-study has facilities in Vaasa city center. Botnia-study has a close collaboration with Vaasa Central Hospital and Vaasa Health Center.
Kaj Lahti, MD., Specialist in internal medicine
Chief Physician, Chief medical officer for Botnia study in Vaasa
Kaj Lahti works as a Chief Physician at the Diabetes Clinic of Vaasa City and is the Chief medical officer for Botnia study in Vaasa.
Annemari Käräjämäki, MD, Specialist in general medicine
Chief Physician, Responsible for DIREVA register and Doctoral student
Annemari Käräjämäki works as a chief physician at Vaasa Central Hospital and as a diabetes physician at the Diabetes Clinic of Vaasa City. She is responsible for the Diabetes Register in Vaasa (DIREVA) and is a doctoral student at University of Helsinki. In her research she is focused on novel subgroups of diabetes and complications related to them.
Britt Stolpe, medical laboratory technologist
Britt Stolpe works as a study nurse at the Vaasa Botnia center. She is responsible for the sample handling, recruitment of study participants and study visits especially for the PPP and PPP Trio projects in Vaasa.
Matleena Lamminaho, nurse
Matleena Lamminaho works as a study nurse at the Vaasa Botnia center. She is responsible for the sample handling, recruitment of study participants and study visits especially for the PPP and PPP Trio projects in Vaasa.
Carola Påhls, Research nurse
Carola Påhls works as a research nurse for the Direva-project in Vaasa.
The Botnia-center in Jakobstad is located in the Folkhälsan Östanlid Hospital.
Bo Isomaa, MD
Diabetes doctor at the Botnia-center in Jakobstad
Bo Isomaa works as a doctor at the Botnia center in Jakobstad. Before he was the coordinator for the PPP Botnia- and Exercise intervention studies in Ostrobothnia region.
Leena Sarelin, medical laboratory technologist
Leena Sarelin works as a study nurse at the Pietarsaari Botnia center. She is responsible for the sample handling, recruitment of study participants and study visits especially for the PPP, PPP Trio and Zinc projects in Pietarsaari.
The Botnia-study was started in 1990 in Närpes, as a collaboration with Närpes Health Center. The operation of the Botnia-center in Närpes ended in October 2020, as the long-time study nurse was retired, but we will continue our collaboration with the health center and possibly conduct some temporary studies at their premises.
We ask study participants to contact Botnia-center in Vaasa or in Helsinki.
Some of the Botnia study's genetic analyses take place in Malmö. Research activities are located at the Clinical Research Centre, Skåne University Hospital in Malmö and Botnia study collaborates with Lund University Diabetes Center (LUDC).
Botnia study in Malmö:
Clinical Research Centre
Jan Waldenströms gata 35, 91:12
Skåne University Hospital Malmö
SE-205 02 MALMÖ
Tel: +46 40 39 12 01