High-throughput targeted and quantitative metabolomics
Analysis of hundreds of polar metabolites in a single ((method using MRM strategy. uitable for tissues, cells, and biofluids (doi: 10.3390/metabo8030044).
Customized targeted quantitative metabolomics
Concentration analysis for ketonebodies, ketoacids, NADs, short-chain fatty acids, folate cycle intermediates or absolute quantification of TCA cycle intermediates (doi: 10.3390/metabo10030103). Suitable for tissues, cells, and biofluids.
High-throughput qualitative metabolomics profiling and custom sets
Qualitative analysis of more than five hundred known standardized metabolites using high-resolution orbitrap Q-Exactive. Suitable also for small sample amounts (i.e. 30 000 cells or 15ul) for biofluids, tissues, cells, stem cells, organoids, spheres, and extracellular vesicles.
Metabolic flux analysis
Isotope enrichment analysis and metabolic flux analysis of central carbon metabolism and other pathways using 13C-, 15N- and dH-tracers. Suitable also for small sample amounts (i.e. 30 000 cells or 10ul) for biofluids, tissues, cells, immune cells, stem cells, organoids, spheres, and extracellular vesicles.
High-throughput targeted and quantitative lipidomics
Analysis of thousand lipid molecular species in a single method using the Lipidyzer platform. Suitable for biofluids (min 25ul), tissues, cells, and extracellular vesicles. More details doi: 10.1021/acs.analchem.1c02826
We offer via collaboration complete metabolomics/lipidomics data analysis using advanced biostatistical and chemometric methods including integrated omics data analysis, figures, tables, and metabolic pathway analysis. Reporting, data quality checks, and documentation are included in the service.
Metabolomics analytical methods under development
New sample types taken into method development via collaboration. Contact the head of the unit.
Demand-based metabolomics services and method development
We are open to develop new metabolomics analytical methods based on user demand. Contact the head of the unit.