Structural and Quantitative Biology Research Program

This research program focuses on modern methods for determining the three-dimensional structure and chemical mechanism of macromolecules and macromolecular complexes. Of particular interest are:

  • the structure of membrane proteins and membrane protein complexes
  • the structure and function of viruses
  • the chemical mechanism of model enzyme systems
  • the mechanisms of redox systems such as cytochrome c oxidase and Complex I

Members of the research program coordinate several structural biology core facilities that house cutting edge infrastructure for cryo-EM, X-ray crystallography and NMR. The program also includes protein chemistry as means of characterizing and identifying the protein components behind these complexes, both as a research service and a core facility.

Structural and Quantitative Biology research groups

Get to know our principal investigators and their research!