This research program focuses on modern methods for determining the three-dimensional structure and chemical mechanism of macromolecules and macromolecular complexes. Of particular interest are:
- structures of membrane proteins and protein complexes
- structure and function of viruses
- mechanisms of model enzymes and redox systems
Members of the research program coordinate several structural biology core facilities that house cutting edge infrastructure for cryo-EM, X-ray crystallography and NMR. The program also includes protein chemistry as means of characterizing and identifying the protein components behind these complexes, both as a research service and a core facility.