Pekka Lappalainen: Actin-based Molecular Machines

The actin cytoskeleton provides force for a large number of cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filament must be precisely controlled during these processes, and consequently defects in regulation of the actin cytoskeleton lead to various diseases including cancer progression, as well as neurological and immunological disorders.

We use a wide range of biophysical, biochemical, cell biological, and genetic approaches to uncover the general principles underlying regulation of the actin cytoskeleton, and to reveal how defects in actin dynamics affect the physiological functions of cells.

We are affiliated to Cell and Tis­sue Dynamics and Struc­tural and Quant­it­at­ive Biology Research Programs.

Read more about Pekka’s and his group's research:

Pekka Lappalainen, PhD, Academy professor

Professor in Quantitative Cell Biology
Institute of Biotechnology, HiLIFE
Biocenter 2, room 5009
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki

Phone: +358 405941533