Adult tissue homeostasis and repair is regulated by stem cells found both within the tissue and recruited from outside the organ. The timing and mechanism governing niche formation and stem cell specification are not known, and similarly, little is known about the regulation of homing and migration of stem cells to the site of injury. To address these fundamental questions in stem cell biology we utilize the continuously growing incisor tooth model whose continuous growth is supported by lifelong maintenance of epithelial stem cells, and stable influx of mesenchymal stem cells. We combine state of the art genomic, cellular, and molecular biology approaches in order to unravel the mechanisms which regulate these stem cell populations during early development and in postnatal life.
Anamaria is a Principal Investigator/Senior Researcher at BI.
Anamaria Balic, MD, PhD
Institute of Biotechnology, HiLIFE
P.O. Box 56 (Viikinkaari 5D)
00014 University of Helsinki
Phone: +358 29 41 59655